JPS57131789A - 1,7-naphthyridine derivative - Google Patents

1,7-naphthyridine derivative

Info

Publication number
JPS57131789A
JPS57131789A JP476781A JP476781A JPS57131789A JP S57131789 A JPS57131789 A JP S57131789A JP 476781 A JP476781 A JP 476781A JP 476781 A JP476781 A JP 476781A JP S57131789 A JPS57131789 A JP S57131789A
Authority
JP
Japan
Prior art keywords
compound
formula
agent
formulai
thrombosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP476781A
Other languages
Japanese (ja)
Other versions
JPH0135836B2 (en
Inventor
Yasumitsu Tamura
Rinkei Chin
Masanobu Fujita
Yasuyuki Kita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP476781A priority Critical patent/JPS57131789A/en
Publication of JPS57131789A publication Critical patent/JPS57131789A/en
Publication of JPH0135836B2 publication Critical patent/JPH0135836B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A 1,7-naphthyridine derivative of formulaI(R1 is H or lower phenylalkyl; R2 is H or lower alkanoyl) and a salt thereof.
EXAMPLE: 1-Benzyl-5-acetyloxy-1,2,3,4-tetrahydro-1,7-naphthyridin-2-one.
USE: Useful as a preventing agent and a remedy for thrombosis having inhibitory action on blood platelet aggregation and antimicrobial action, and further as a synthetic intermediate for a compound of formula II which is useful as a preventing agent and a remedy for angina pectoris, arrhythmia and thrombosis and a hypotensive agent.
PROCESS: A compound of formula III (R1' is lower phenylalkyl; R2' is lower alkanoyl) is reacted with a compound of formula IV (X1 is halogen) in a suitable solvent at 100W150°C to give a compound of formula V, which is then reacted with a dehydrogenating agent to afford the compound of formulaI(R1 and R2 are not H).
COPYRIGHT: (C)1982,JPO&Japio
JP476781A 1981-01-13 1981-01-13 1,7-naphthyridine derivative Granted JPS57131789A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP476781A JPS57131789A (en) 1981-01-13 1981-01-13 1,7-naphthyridine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP476781A JPS57131789A (en) 1981-01-13 1981-01-13 1,7-naphthyridine derivative

Publications (2)

Publication Number Publication Date
JPS57131789A true JPS57131789A (en) 1982-08-14
JPH0135836B2 JPH0135836B2 (en) 1989-07-27

Family

ID=11593006

Family Applications (1)

Application Number Title Priority Date Filing Date
JP476781A Granted JPS57131789A (en) 1981-01-13 1981-01-13 1,7-naphthyridine derivative

Country Status (1)

Country Link
JP (1) JPS57131789A (en)

Also Published As

Publication number Publication date
JPH0135836B2 (en) 1989-07-27

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