JPS5692872A - 177cyclopropylmethyll144hydroxyy33methoxyy morphinann66one*its acid addition salt and its pharmaceutical use - Google Patents

177cyclopropylmethyll144hydroxyy33methoxyy morphinann66one*its acid addition salt and its pharmaceutical use

Info

Publication number
JPS5692872A
JPS5692872A JP17481080A JP17481080A JPS5692872A JP S5692872 A JPS5692872 A JP S5692872A JP 17481080 A JP17481080 A JP 17481080A JP 17481080 A JP17481080 A JP 17481080A JP S5692872 A JPS5692872 A JP S5692872A
Authority
JP
Japan
Prior art keywords
acid addition
addition salt
pharmaceutical use
pharmaceutical
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17481080A
Other languages
English (en)
Inventor
Kumaaru Razudan Raji
Chiyandora Gooshiyu Aniru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sisa Inc
Original Assignee
Sisa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sisa Inc filed Critical Sisa Inc
Publication of JPS5692872A publication Critical patent/JPS5692872A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP17481080A 1979-12-17 1980-12-12 177cyclopropylmethyll144hydroxyy33methoxyy morphinann66one*its acid addition salt and its pharmaceutical use Pending JPS5692872A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/104,587 US4260617A (en) 1979-12-17 1979-12-17 17-Cyclopropylmethyl-14-hydroxy-3-methoxymorphinan-6-one and method of treating pain with it

Publications (1)

Publication Number Publication Date
JPS5692872A true JPS5692872A (en) 1981-07-27

Family

ID=22301273

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17481080A Pending JPS5692872A (en) 1979-12-17 1980-12-12 177cyclopropylmethyll144hydroxyy33methoxyy morphinann66one*its acid addition salt and its pharmaceutical use

Country Status (4)

Country Link
US (1) US4260617A (ja)
EP (1) EP0030685B1 (ja)
JP (1) JPS5692872A (ja)
DE (1) DE3062232D1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362733A (en) * 1981-06-29 1982-12-07 Miles Laboratories, Inc. N-Cyclopropylmethyl-14-ethoxymorphinan-6-one compounds exhibiting mixed analgesic/narcotic antagonist activity and precursors therefore
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3166559A (en) * 1965-01-19 J-lower alkoxy-x-phenyloxy-ix-hydroxy-
US3201403A (en) * 1965-08-17 Alkoxy-substituted-n lower alkanoyl morpiiinans
US3654280A (en) * 1968-03-21 1972-04-04 Shionogi & Co L-n allylic-3-hydroxy-6-oxomorphinans
US4161597A (en) * 1976-12-20 1979-07-17 Research Corporation N-alkyl-14-hydroxymorphinans and derivatives
US4141897A (en) * 1976-12-20 1979-02-27 Research Corporation N-dealkylation of N-alkyl-14-hydroxymorphinans and derivatives thereof
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them

Also Published As

Publication number Publication date
EP0030685B1 (en) 1983-03-02
DE3062232D1 (de) 1983-04-07
US4260617A (en) 1981-04-07
EP0030685A3 (en) 1981-09-09
EP0030685A2 (en) 1981-06-24

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