DE3062232D1 - 17-cyclopropylmethyl-3-methoxy-14-hydroxy-morphinan-6-one - Google Patents

17-cyclopropylmethyl-3-methoxy-14-hydroxy-morphinan-6-one

Info

Publication number
DE3062232D1
DE3062232D1 DE8080107601T DE3062232T DE3062232D1 DE 3062232 D1 DE3062232 D1 DE 3062232D1 DE 8080107601 T DE8080107601 T DE 8080107601T DE 3062232 T DE3062232 T DE 3062232T DE 3062232 D1 DE3062232 D1 DE 3062232D1
Authority
DE
Germany
Prior art keywords
morphinan
cyclopropylmethyl
methoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080107601T
Other languages
English (en)
Inventor
Raj Kumar Razdan
Anil Chandra Ghosh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sisa Inc
Original Assignee
Sisa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sisa Inc filed Critical Sisa Inc
Application granted granted Critical
Publication of DE3062232D1 publication Critical patent/DE3062232D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
DE8080107601T 1979-12-17 1980-12-04 17-cyclopropylmethyl-3-methoxy-14-hydroxy-morphinan-6-one Expired DE3062232D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/104,587 US4260617A (en) 1979-12-17 1979-12-17 17-Cyclopropylmethyl-14-hydroxy-3-methoxymorphinan-6-one and method of treating pain with it

Publications (1)

Publication Number Publication Date
DE3062232D1 true DE3062232D1 (de) 1983-04-07

Family

ID=22301273

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080107601T Expired DE3062232D1 (de) 1979-12-17 1980-12-04 17-cyclopropylmethyl-3-methoxy-14-hydroxy-morphinan-6-one

Country Status (4)

Country Link
US (1) US4260617A (de)
EP (1) EP0030685B1 (de)
JP (1) JPS5692872A (de)
DE (1) DE3062232D1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362733A (en) * 1981-06-29 1982-12-07 Miles Laboratories, Inc. N-Cyclopropylmethyl-14-ethoxymorphinan-6-one compounds exhibiting mixed analgesic/narcotic antagonist activity and precursors therefore
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3201403A (en) * 1965-08-17 Alkoxy-substituted-n lower alkanoyl morpiiinans
US3166559A (en) * 1965-01-19 J-lower alkoxy-x-phenyloxy-ix-hydroxy-
US3654280A (en) * 1968-03-21 1972-04-04 Shionogi & Co L-n allylic-3-hydroxy-6-oxomorphinans
US4161597A (en) * 1976-12-20 1979-07-17 Research Corporation N-alkyl-14-hydroxymorphinans and derivatives
US4141897A (en) * 1976-12-20 1979-02-27 Research Corporation N-dealkylation of N-alkyl-14-hydroxymorphinans and derivatives thereof
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them

Also Published As

Publication number Publication date
EP0030685A2 (de) 1981-06-24
EP0030685A3 (en) 1981-09-09
JPS5692872A (en) 1981-07-27
EP0030685B1 (de) 1983-03-02
US4260617A (en) 1981-04-07

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee