JPS5692288A - Novel antibiotic mitomycin compound*drug mixture containing it for treating animal tumor and treatment for animal tumor - Google Patents
Novel antibiotic mitomycin compound*drug mixture containing it for treating animal tumor and treatment for animal tumorInfo
- Publication number
- JPS5692288A JPS5692288A JP17194080A JP17194080A JPS5692288A JP S5692288 A JPS5692288 A JP S5692288A JP 17194080 A JP17194080 A JP 17194080A JP 17194080 A JP17194080 A JP 17194080A JP S5692288 A JPS5692288 A JP S5692288A
- Authority
- JP
- Japan
- Prior art keywords
- animal tumor
- treatment
- mixture containing
- drug mixture
- novel antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/100,331 US4268676A (en) | 1979-12-05 | 1979-12-05 | Mitomycin analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5692288A true JPS5692288A (en) | 1981-07-25 |
Family
ID=22279228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17194080A Pending JPS5692288A (en) | 1979-12-05 | 1980-12-04 | Novel antibiotic mitomycin compound*drug mixture containing it for treating animal tumor and treatment for animal tumor |
Country Status (3)
Country | Link |
---|---|
US (1) | US4268676A (ja) |
JP (1) | JPS5692288A (ja) |
FR (2) | FR2478101A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4691024A (en) * | 1984-06-01 | 1987-09-01 | Kyowa Hakko Kogyo Kabushiki Kaisha | New mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them |
US4771068A (en) * | 1985-04-10 | 1988-09-13 | Kyowa Hakko Kogyo Kabushiki Kaisha | Mitomycin derivatives having anti-tumor and antibacterial utility |
JPS63316781A (ja) * | 1987-06-12 | 1988-12-26 | ブリストル―マイアーズ スクイブ コムパニー | マイトマイシン類似体 |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4460599A (en) * | 1979-12-05 | 1984-07-17 | University Patents, Inc. | Mitomycin analogs |
US4617389A (en) * | 1981-05-15 | 1986-10-14 | University Patents, Inc. | Mitomycin analogs |
NZ199617A (en) * | 1981-05-15 | 1985-08-30 | University Patents Inc | Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions |
US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
DE116208T1 (de) * | 1982-12-07 | 1985-02-28 | Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo | Mitomycin-analoge. |
NZ206932A (en) * | 1983-02-07 | 1987-08-31 | University Patents Inc | Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions |
US4803212A (en) * | 1983-04-11 | 1989-02-07 | Bristol-Myers Company | Amino disulfides |
US4579737A (en) * | 1983-05-09 | 1986-04-01 | Bristol-Myers Company | Bis-amidines |
US4642352A (en) * | 1983-12-23 | 1987-02-10 | Bristol-Myers Company | Acylamino mitosanes |
US4866180A (en) * | 1984-02-24 | 1989-09-12 | Bristol-Myers Company | Amino disulfide thiol exchange products |
US4691023A (en) * | 1984-02-24 | 1987-09-01 | Bristol-Myers Company | Amino disulfides |
US5098926A (en) * | 1984-09-04 | 1992-03-24 | University Patents, Inc. | 6-substituted mitomycin analogs |
US4720543A (en) * | 1985-06-06 | 1988-01-19 | Georgetown University | 1a-7-substituted derivatives of mitomycin and uses thereof |
JPS63150282A (ja) * | 1986-12-13 | 1988-06-22 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
WO1990001931A1 (en) * | 1988-08-23 | 1990-03-08 | Georgetown University | Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof |
US5091523A (en) * | 1990-04-25 | 1992-02-25 | Georgetown University | Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL129868C (ja) * | 1963-06-07 | |||
DE1570029A1 (de) * | 1964-07-09 | 1970-04-09 | Kyowa Hakko Kogyo Kk | Verfahren zur Herstellung von Mitosanverbindungen |
FR1449947A (fr) * | 1964-08-25 | 1966-05-06 | Kyowa Hakko Kogyo Kk | Procédé de préparation de mitomycines a 7-substituées |
US3332944A (en) * | 1964-11-02 | 1967-07-25 | American Cyanamid Co | Antibiotic derivatives of mitomycins a, b, c and porfiromycin |
-
1979
- 1979-12-05 US US06/100,331 patent/US4268676A/en not_active Expired - Lifetime
-
1980
- 1980-12-04 FR FR8025775A patent/FR2478101A1/fr active Granted
- 1980-12-04 JP JP17194080A patent/JPS5692288A/ja active Pending
-
1981
- 1981-04-24 FR FR8108250A patent/FR2477016A1/fr active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4691024A (en) * | 1984-06-01 | 1987-09-01 | Kyowa Hakko Kogyo Kabushiki Kaisha | New mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them |
US4771068A (en) * | 1985-04-10 | 1988-09-13 | Kyowa Hakko Kogyo Kabushiki Kaisha | Mitomycin derivatives having anti-tumor and antibacterial utility |
JPS63316781A (ja) * | 1987-06-12 | 1988-12-26 | ブリストル―マイアーズ スクイブ コムパニー | マイトマイシン類似体 |
JPH0563476B2 (ja) * | 1987-06-12 | 1993-09-10 | Bristol Myers Squibb Co |
Also Published As
Publication number | Publication date |
---|---|
FR2478101A1 (fr) | 1981-09-18 |
FR2477016A1 (fr) | 1981-09-04 |
FR2478101B1 (ja) | 1984-06-08 |
FR2477016B1 (ja) | 1984-06-08 |
US4268676A (en) | 1981-05-19 |
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