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Santen Pharmaceutical Co Ltd
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Santen Pharmaceutical Co Ltd
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Priority to JP17013879ApriorityCriticalpatent/JPS5690991A/en
Publication of JPS5690991ApublicationCriticalpatent/JPS5690991A/en
Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor
(AREA)
Abstract
PURPOSE: To manufacture a derivative of thiazolidine carboxylic acid which is useful as a hypotensive drug industrially at a low cost, by the electrolytic reduction of org. thiazosulfide having a specific structural formula.
CONSTITUTION: A compound shown by formula I, or its NH4 salt, org. amine salt, or alkali metal salt, is electrolytically reduced using platinum or silver, which is generally used, as an electrode to form a compound shown by a formula II. The electrolytic reduction is performed at a voltage of 0.5W50V, preferably 1W10V 0.2W25A/dcm2 current density. As a compound shown by the formula I is used for example: (4R,4'R)-3,3'-[3, 3'-dithiobis(propanoyl)]bis[2-[2-(2-hydroxyphenyl)]-4- thiazolidine carboxylic acid ], and an example for the compound shown by the formula 11 is (4R)-2-(2-hydroxyphenyl)-3-(3-mercaptopropanoyl)-4-thiazolidine carboxylic acid.
COPYRIGHT: (C)1981,JPO&Japio
JP17013879A1979-12-251979-12-25Manufacture of thiol compound
PendingJPS5690991A
(en)
7-(Aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds.
Substituted 2-propenyl derivatives of nitrogen heterocycles,processes for the preparation thereof,fungicidal compositions containing the same and methods for the use thereof
NEW 1-ACETONYL-2- (PHENYLIMINO) -IMIDAZOLIDINES OF THE SAEURE ADDITION SALT CONTAINING MEDICAMENTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF