JPS5681450A

JPS5681450A - Determination method for glucagon

Determination method for glucagon

Info

Publication number: JPS5681450A
Authority: JP; Japan
Prior art keywords: glucagon; formula; galactosidase; fragment; conjugate
Prior art date: 1980-10-23
Legal status : Granted

Application number

JP14873280A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6341425B2 (enrdf_load_stackoverflow

Inventor

Nobuaki Nakagawa

Kikuo Kotani

Kunio Ooyama

Ko Morita

Shigeo Kuzuki

Toshiharu Noda

Current Assignee

Toyo Jozo KK

Original Assignee

Toyo Jozo KK

Priority date

1980-10-23

Filing date

1980-10-23

Publication date

1981-07-03

1980-10-23 Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK

1980-10-23 Priority to JP14873280A priority Critical patent/JPS5681450A/ja

1981-07-03 Publication of JPS5681450A publication Critical patent/JPS5681450A/ja

1988-08-17 Publication of JPS6341425B2 publication Critical patent/JPS6341425B2/ja

Status Granted legal-status Critical Current

Links

MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title abstract 6
102000051325 Glucagon Human genes 0.000 title abstract 4
108060003199 Glucagon Proteins 0.000 title abstract 4
229960004666 glucagon Drugs 0.000 title abstract 4
108090000765 processed proteins & peptides Proteins 0.000 abstract 3
239000003431 cross linking reagent Substances 0.000 abstract 2
230000009257 reactivity Effects 0.000 abstract 2
125000002947 alkylene group Chemical group 0.000 abstract 1
102000005936 beta-Galactosidase Human genes 0.000 abstract 1
108010005774 beta-Galactosidase Proteins 0.000 abstract 1
230000001900 immune effect Effects 0.000 abstract 1
230000008105 immune reaction Effects 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
WREDNSAXDZCLCP-UHFFFAOYSA-N methanedithioic acid Chemical compound SC=S WREDNSAXDZCLCP-UHFFFAOYSA-N 0.000 abstract 1
125000000962 organic group Chemical group 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
125000006850 spacer group Chemical group 0.000 abstract 1