JPS5651451A - Preparation of indole or its derivative - Google Patents

Preparation of indole or its derivative

Info

Publication number
JPS5651451A
JPS5651451A JP12676079A JP12676079A JPS5651451A JP S5651451 A JPS5651451 A JP S5651451A JP 12676079 A JP12676079 A JP 12676079A JP 12676079 A JP12676079 A JP 12676079A JP S5651451 A JPS5651451 A JP S5651451A
Authority
JP
Japan
Prior art keywords
reaction
derivative
cuo
mno
sio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12676079A
Other languages
Japanese (ja)
Other versions
JPS6130657B2 (en
Inventor
Tadamitsu Kiyoura
Yasuo Kogure
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP12676079A priority Critical patent/JPS5651451A/en
Publication of JPS5651451A publication Critical patent/JPS5651451A/en
Publication of JPS6130657B2 publication Critical patent/JPS6130657B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain the titled compound in high yield and in one stage, by the simple reaction of readily available and inexpensive N-β-hydroxyethylaniline or its derivative, in the presence of a catalyst consisting of copper as a main component, in the atmosphere of hydrogen.
CONSTITUTION: N-β-hydroxyaniline or its nuclear-substituted derivative is reacted in atmosphere of hydrogen, in the presence of a catalyst consisting of CuO-MaO- MnO2-SiO2, to give indole or its derviative. The starting material is prepared by the reaction of aniline which is available in a large amount inexpensive, with ethylene oxide, in high yield. The catalyst may preferable consist of 10W40mol% CuO, 10W30mol% MgO, 2W20mol% MnO2and 10W78mol% SiO2. The starting material has no problem of balance between o-and p-isomers, and the reaction may proceed without a comp licated stage. Therefore, the method is very advantageous industrially.
COPYRIGHT: (C)1981,JPO&Japio
JP12676079A 1979-10-03 1979-10-03 Preparation of indole or its derivative Granted JPS5651451A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12676079A JPS5651451A (en) 1979-10-03 1979-10-03 Preparation of indole or its derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12676079A JPS5651451A (en) 1979-10-03 1979-10-03 Preparation of indole or its derivative

Publications (2)

Publication Number Publication Date
JPS5651451A true JPS5651451A (en) 1981-05-09
JPS6130657B2 JPS6130657B2 (en) 1986-07-15

Family

ID=14943236

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12676079A Granted JPS5651451A (en) 1979-10-03 1979-10-03 Preparation of indole or its derivative

Country Status (1)

Country Link
JP (1) JPS5651451A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5910565A (en) * 1982-07-08 1984-01-20 Mitsui Toatsu Chem Inc Preparation of indole compound

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5910565A (en) * 1982-07-08 1984-01-20 Mitsui Toatsu Chem Inc Preparation of indole compound
JPS6356222B2 (en) * 1982-07-08 1988-11-07 Mitsui Toatsu Chemicals

Also Published As

Publication number Publication date
JPS6130657B2 (en) 1986-07-15

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