JPS5651442A - Ornithine derivative - Google Patents
Ornithine derivativeInfo
- Publication number
- JPS5651442A JPS5651442A JP12658079A JP12658079A JPS5651442A JP S5651442 A JPS5651442 A JP S5651442A JP 12658079 A JP12658079 A JP 12658079A JP 12658079 A JP12658079 A JP 12658079A JP S5651442 A JPS5651442 A JP S5651442A
- Authority
- JP
- Japan
- Prior art keywords
- give
- formula
- action
- water
- extracted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:δ-Benzoyl-γ-hydroxyornithine shown by the formula.
USE: An inhibitor for ornithinedecarboxylase. Being expected to have an action as carcinostatic or contraceptive, the derivative has an action as an immune reactivator.
PROCESS: Seed, pod, stalk, leaf, etc. of Vicia pseudo-orobus Fischer et Meyer is extracted with an aqueous solvent (e.g., water, water-ethanol, etc.) to give an extracted solution, which is subjected to chromatography using an ion exchange resin. The solution is then purified by column chromatography using cellulose, and crystallized to give a compound shown by the formula.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12658079A JPS5651442A (en) | 1979-10-01 | 1979-10-01 | Ornithine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12658079A JPS5651442A (en) | 1979-10-01 | 1979-10-01 | Ornithine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5651442A true JPS5651442A (en) | 1981-05-09 |
JPS6215065B2 JPS6215065B2 (en) | 1987-04-06 |
Family
ID=14938681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12658079A Granted JPS5651442A (en) | 1979-10-01 | 1979-10-01 | Ornithine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5651442A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0248217A2 (en) * | 1986-05-06 | 1987-12-09 | Merrell Dow Pharmaceuticals Inc. | Use of ornithine decarboxylase inhibitor for preparing a medicament for use in the treatment, in conjuction with LAK cells and interleukin-2, of tumors |
-
1979
- 1979-10-01 JP JP12658079A patent/JPS5651442A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0248217A2 (en) * | 1986-05-06 | 1987-12-09 | Merrell Dow Pharmaceuticals Inc. | Use of ornithine decarboxylase inhibitor for preparing a medicament for use in the treatment, in conjuction with LAK cells and interleukin-2, of tumors |
Also Published As
Publication number | Publication date |
---|---|
JPS6215065B2 (en) | 1987-04-06 |
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