JPS5646839A - 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound - Google Patents

4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound

Info

Publication number
JPS5646839A
JPS5646839A JP12316179A JP12316179A JPS5646839A JP S5646839 A JPS5646839 A JP S5646839A JP 12316179 A JP12316179 A JP 12316179A JP 12316179 A JP12316179 A JP 12316179A JP S5646839 A JPS5646839 A JP S5646839A
Authority
JP
Japan
Prior art keywords
compound
cyclodextrin
allyloxy
chlorophenylacetic acid
kneading
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12316179A
Other languages
Japanese (ja)
Inventor
Yoshinori Matsuoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Yuka Pharmaceutical Co Ltd
Original Assignee
Mitsubishi Yuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Yuka Pharmaceutical Co Ltd filed Critical Mitsubishi Yuka Pharmaceutical Co Ltd
Priority to JP12316179A priority Critical patent/JPS5646839A/en
Publication of JPS5646839A publication Critical patent/JPS5646839A/en
Pending legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To titled compound almost free from irritant odor and taste, useful as an antiphlogistic analgesic agent of various administration forms, and obtained by including 4-allyloxy-3-chlorophenylacetic acid in cyclodextrin.
CONSTITUTION: The titled clathrate compound is prepared by including 4-allyloxy-3-chloro-phenylacetic acid (A) in cyclodextrin. The inclusion is preferably carried out by the solution process or the kneading process. In the sloution process, the objective compound is prepared by adding the compound (A) or its alcohol solution, etc. to the saturated aqueous solution of cyclodextrin, and stirring the mixture at 20W60°C for 5W10hr; and in the kneading process, the powdery product is obtained by adding the compound (A) to an aqueous paste of cyclodextrin, kneading the mixture at 20W60°C for 3W8hr, and drying the product.
COPYRIGHT: (C)1981,JPO&Japio
JP12316179A 1979-09-27 1979-09-27 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound Pending JPS5646839A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12316179A JPS5646839A (en) 1979-09-27 1979-09-27 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12316179A JPS5646839A (en) 1979-09-27 1979-09-27 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound

Publications (1)

Publication Number Publication Date
JPS5646839A true JPS5646839A (en) 1981-04-28

Family

ID=14853684

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12316179A Pending JPS5646839A (en) 1979-09-27 1979-09-27 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound

Country Status (1)

Country Link
JP (1) JPS5646839A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762702A (en) * 1984-11-05 1988-08-09 Gerhard Gergely Pharmaceutical preparation containing ibuprofen and a process for its preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762702A (en) * 1984-11-05 1988-08-09 Gerhard Gergely Pharmaceutical preparation containing ibuprofen and a process for its preparation

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