JPS5640608A - Pharmaceutical preparation for rectal administration - Google Patents
Pharmaceutical preparation for rectal administrationInfo
- Publication number
- JPS5640608A JPS5640608A JP11569679A JP11569679A JPS5640608A JP S5640608 A JPS5640608 A JP S5640608A JP 11569679 A JP11569679 A JP 11569679A JP 11569679 A JP11569679 A JP 11569679A JP S5640608 A JPS5640608 A JP S5640608A
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical preparation
- rectal administration
- microcapsules
- absorption
- ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE: A pharmaceutical preparation for rectal administration with the duration of action improved by prolonging the absorption of an active ingredient, being obtained by compounding the microcapsules of the ingredient with a base, etc. together.
CONSTITUTION: A pharmaceutical preparation for rectal administration having the prolonged absorption of an active ingredient, consisting of the ingredient, e.g., indomethacin, diclofenac sodium, aspirin, and 1-(2'-tetrahydrofuryl)-5-fluorouracil, in the form of microcapsules, one or more bases selected from polyethylene glycol, cacao butter, Tween, Witepsol (manufactured by Chemische Werke Witten), etc., and, if desired, additives such as a preservative, a surface active agent, an antioxidant and a coloring agent. The coating material of the microcapsules is e.g., polyhexamethylene terephthalamide or polyhexamethylene sebacamide. Since the absorption of an active ingredient from the rectum is prolonged, the long duration of action, improvement in safety, decrease in administration rate, etc. can be achieved.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11569679A JPS5640608A (en) | 1979-09-11 | 1979-09-11 | Pharmaceutical preparation for rectal administration |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11569679A JPS5640608A (en) | 1979-09-11 | 1979-09-11 | Pharmaceutical preparation for rectal administration |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5640608A true JPS5640608A (en) | 1981-04-16 |
Family
ID=14668968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11569679A Pending JPS5640608A (en) | 1979-09-11 | 1979-09-11 | Pharmaceutical preparation for rectal administration |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5640608A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05194223A (en) * | 1992-09-11 | 1993-08-03 | Kyorin Pharmaceut Co Ltd | Sustained release suppository composition for 3-isobutyryl-2-isopropylpyrazolo(1,5-a)pyridine |
WO2002003954A3 (en) * | 2000-07-07 | 2002-05-10 | Anestic Aps | Non swellable suppository comprising at least one biocompatible, non-biodegradable polymer and a controlled release formulation |
-
1979
- 1979-09-11 JP JP11569679A patent/JPS5640608A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05194223A (en) * | 1992-09-11 | 1993-08-03 | Kyorin Pharmaceut Co Ltd | Sustained release suppository composition for 3-isobutyryl-2-isopropylpyrazolo(1,5-a)pyridine |
WO2002003954A3 (en) * | 2000-07-07 | 2002-05-10 | Anestic Aps | Non swellable suppository comprising at least one biocompatible, non-biodegradable polymer and a controlled release formulation |
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