JPS563327B2 - - Google Patents

Info

Publication number
JPS563327B2
JPS563327B2 JP13894377A JP13894377A JPS563327B2 JP S563327 B2 JPS563327 B2 JP S563327B2 JP 13894377 A JP13894377 A JP 13894377A JP 13894377 A JP13894377 A JP 13894377A JP S563327 B2 JPS563327 B2 JP S563327B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP13894377A
Other languages
Japanese (ja)
Other versions
JPS5481260A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP13894377A priority Critical patent/JPS5481260A/ja
Priority to GB7844232A priority patent/GB2010254B/en
Priority to FR7832652A priority patent/FR2409265A1/fr
Priority to DE2850485A priority patent/DE2850485C3/de
Publication of JPS5481260A publication Critical patent/JPS5481260A/ja
Priority to US06/071,486 priority patent/US4230719A/en
Publication of JPS563327B2 publication Critical patent/JPS563327B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/29Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with halogen-containing compounds which may be formed in situ
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/08Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
JP13894377A 1977-11-21 1977-11-21 2-4-(3-methyl-2-thienyl)phenyl propionic acid, its nontoxic salt and antiphlogistics, analgesics, and antirheumatics containing them Granted JPS5481260A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP13894377A JPS5481260A (en) 1977-11-21 1977-11-21 2-4-(3-methyl-2-thienyl)phenyl propionic acid, its nontoxic salt and antiphlogistics, analgesics, and antirheumatics containing them
GB7844232A GB2010254B (en) 1977-11-21 1978-11-13 2-4-(3-methyl-2-thienyl)phenyl propionic acid and pharmaceutically acceptable salt thereof and method for treating symptoms of inflammation and pain
FR7832652A FR2409265A1 (fr) 1977-11-21 1978-11-20 Acide 2-(4-(3-methyl-2-thienyl)phenyl)propionique et ses sels pharmaceutiquement acceptables, leur procede de preparation et leur application en therapeutique
DE2850485A DE2850485C3 (de) 1977-11-21 1978-11-21 2-[4-[3-Methyl-thienyl(2)]-phenyl]-propionsäure, pharmazeutisch verträgliches Salz derselben, Verfahren zu deren Herstellung und deren Verwendung zur Bekämpfung von rheumatischen Schmerzzuständen und Entzündungen
US06/071,486 US4230719A (en) 1977-11-21 1979-08-31 Novel 2-[4-(3-methyl-2-thienyl)phenyl]propionic acid and pharmaceutically acceptable salt thereof and method for treating symptoms of inflammation and pain

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13894377A JPS5481260A (en) 1977-11-21 1977-11-21 2-4-(3-methyl-2-thienyl)phenyl propionic acid, its nontoxic salt and antiphlogistics, analgesics, and antirheumatics containing them

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP5989580A Division JPS6019909B2 (ja) 1980-05-08 1980-05-08 2―〔4―(3―メチル―2―チエニル)フエニル〕プロピオン酸及びその非毒性塩

Publications (2)

Publication Number Publication Date
JPS5481260A JPS5481260A (en) 1979-06-28
JPS563327B2 true JPS563327B2 (fr) 1981-01-24

Family

ID=15233767

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13894377A Granted JPS5481260A (en) 1977-11-21 1977-11-21 2-4-(3-methyl-2-thienyl)phenyl propionic acid, its nontoxic salt and antiphlogistics, analgesics, and antirheumatics containing them

Country Status (4)

Country Link
JP (1) JPS5481260A (fr)
DE (1) DE2850485C3 (fr)
FR (1) FR2409265A1 (fr)
GB (1) GB2010254B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3049405A1 (de) * 1980-12-23 1982-07-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue derivate von antiphlogistisch wirksamen carbonsaeuren, ihre herstellung und medizinische anwendung
GB2181728B (en) * 1985-10-21 1990-01-24 Indian Drugs & Pharma 4-(3-thienyl)phenylalkanoic acids and derivatives and process for their preparation
TW200827343A (en) 2006-09-11 2008-07-01 Fuji Yakuhin Co Ltd Novel phenylacetic acid derivative

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1119334A (en) * 1964-11-27 1968-07-10 Merck & Co Inc Para-substituted phenylacetic acids, aldehydes and alocohols and their derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1119334A (en) * 1964-11-27 1968-07-10 Merck & Co Inc Para-substituted phenylacetic acids, aldehydes and alocohols and their derivatives

Also Published As

Publication number Publication date
FR2409265A1 (fr) 1979-06-15
DE2850485B2 (de) 1981-01-08
JPS5481260A (en) 1979-06-28
FR2409265B1 (fr) 1981-07-10
DE2850485C3 (de) 1981-12-03
DE2850485A1 (de) 1979-05-23
GB2010254A (en) 1979-06-27
GB2010254B (en) 1982-02-17

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