JPS5631646A - Sensitized latex for herpes virus infection diagnosis - Google Patents

Sensitized latex for herpes virus infection diagnosis

Info

Publication number
JPS5631646A
JPS5631646A JP10667479A JP10667479A JPS5631646A JP S5631646 A JPS5631646 A JP S5631646A JP 10667479 A JP10667479 A JP 10667479A JP 10667479 A JP10667479 A JP 10667479A JP S5631646 A JPS5631646 A JP S5631646A
Authority
JP
Japan
Prior art keywords
antigen
latex
herpes virus
diagnosis
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10667479A
Other languages
Japanese (ja)
Inventor
Tetsuo Tomiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUJI ZOKI SEIYAKU
Fujirebio Inc
Original Assignee
FUJI ZOKI SEIYAKU
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUJI ZOKI SEIYAKU, Fujirebio Inc filed Critical FUJI ZOKI SEIYAKU
Priority to JP10667479A priority Critical patent/JPS5631646A/en
Publication of JPS5631646A publication Critical patent/JPS5631646A/en
Pending legal-status Critical Current

Links

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To enable the diagnosis with high sensitivity simply and in a short time, by using the received latex agglutination, by coupling the herpes virus antigen to the polystyrene latex.
CONSTITUTION: After cultivating the herpes virus through the use of cell such as VERO cell or hatched egg, the suspension including the antigen picked up from them is made. This antigen is fed to the solution that the polystyrene latex having the specific gravity of 1.1 or more is floated in the phosphate buffer salt solution (PBS) to obtain the sensitized latex. This is suspended in the preservation liquid and held at 4W6°C temperature for ling term storage. Further, it can be stored with freezing the drying. The sensitized latex liquid or frozed and dried product is diluted with the specified dilution liquid, the presence of the agglutination is observed with the micro-titration method in addition of it to the secrum of a patient, and the agglutinate is regarded as positive. The reciprocal of the maximum dilution number of secrum is taken as the value of antigen. Thus, the diagnosis can be made with the high sensitivity about 100 times the measurement of conventional complement fixation reaction and in about 10hr.
COPYRIGHT: (C)1981,JPO&Japio
JP10667479A 1979-08-23 1979-08-23 Sensitized latex for herpes virus infection diagnosis Pending JPS5631646A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10667479A JPS5631646A (en) 1979-08-23 1979-08-23 Sensitized latex for herpes virus infection diagnosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10667479A JPS5631646A (en) 1979-08-23 1979-08-23 Sensitized latex for herpes virus infection diagnosis

Publications (1)

Publication Number Publication Date
JPS5631646A true JPS5631646A (en) 1981-03-31

Family

ID=14439609

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10667479A Pending JPS5631646A (en) 1979-08-23 1979-08-23 Sensitized latex for herpes virus infection diagnosis

Country Status (1)

Country Link
JP (1) JPS5631646A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60124010A (en) * 1983-12-07 1985-07-02 Sanyo Electric Co Ltd Production of reinforcing core for composite magnetic head
JPS60155974A (en) * 1983-08-30 1985-08-16 ジエネンテク,インコ−ポレイテツド Diagnostic product changed into molecular clone
US4663277A (en) * 1983-05-20 1987-05-05 Profile Diagnostic Sciences Inc. Virus detection method and materials
US5155021A (en) * 1989-02-09 1992-10-13 Eastman Kodak Company Method and kit for determination of herpes simplex viral antigen by direct binding to polymeric particles
WO2002103356A1 (en) 2001-06-18 2002-12-27 Alexander Schoenfeld Prophylactic article useful for both protection and diagnosis and method for use and production thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663277A (en) * 1983-05-20 1987-05-05 Profile Diagnostic Sciences Inc. Virus detection method and materials
JPS60155974A (en) * 1983-08-30 1985-08-16 ジエネンテク,インコ−ポレイテツド Diagnostic product changed into molecular clone
JPS60124010A (en) * 1983-12-07 1985-07-02 Sanyo Electric Co Ltd Production of reinforcing core for composite magnetic head
US5155021A (en) * 1989-02-09 1992-10-13 Eastman Kodak Company Method and kit for determination of herpes simplex viral antigen by direct binding to polymeric particles
WO2002103356A1 (en) 2001-06-18 2002-12-27 Alexander Schoenfeld Prophylactic article useful for both protection and diagnosis and method for use and production thereof

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