JPS562555A - Aqueous solvent for cohesion test - Google Patents

Aqueous solvent for cohesion test

Info

Publication number
JPS562555A
JPS562555A JP7937379A JP7937379A JPS562555A JP S562555 A JPS562555 A JP S562555A JP 7937379 A JP7937379 A JP 7937379A JP 7937379 A JP7937379 A JP 7937379A JP S562555 A JPS562555 A JP S562555A
Authority
JP
Japan
Prior art keywords
cohesion
ions
antigen
antibody
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7937379A
Other languages
Japanese (ja)
Other versions
JPS6022295B2 (en
Inventor
Kazumi Fukuyama
Midori Nagatomo
Yatsuhiro Kamimura
Satoru Funakoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Priority to JP7937379A priority Critical patent/JPS6022295B2/en
Publication of JPS562555A publication Critical patent/JPS562555A/en
Publication of JPS6022295B2 publication Critical patent/JPS6022295B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To improve detection specificity by containing dihydric metal ions such as Mg++ and Zn++ and a chelating agent to specific concentrations when measuring an antigen and antibody by mixing the antigen or antibody and a sample in an aqueous solvent by immune reaction and then by tracing the agglutination.
CONSTITUTION: In a cohesion test based upon immune reaction, not less one kind of dihydric matal ions such as Be, Mg, Ca, Sr, Ba, Fe, Zn, and Cd is mixed in water, a solution of physiologic salt, various buffer liquids, a serum solution, a synthetic polymer solution, or a solution obtained by combining them to a concentration of 0.001W1M. In another way, a chelating agent such as ethylenediamine 4 acetate is mixed to 0.005W1M together with the above-mentioned ions. Thus, when an antigen or antibody and sample are traced in a double diluting method, nonspecific cohesion is suppressed excellently and an aqeuous solvent of excellent specific cohesion can be obtained. Since the chelating agent is used together, the nonspecific cohesion is further suppressed in comparison with the use of dihydric ions only.
COPYRIGHT: (C)1981,JPO&Japio
JP7937379A 1979-06-22 1979-06-22 Aqueous solvent for red blood cell agglutination test Expired JPS6022295B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7937379A JPS6022295B2 (en) 1979-06-22 1979-06-22 Aqueous solvent for red blood cell agglutination test

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7937379A JPS6022295B2 (en) 1979-06-22 1979-06-22 Aqueous solvent for red blood cell agglutination test

Publications (2)

Publication Number Publication Date
JPS562555A true JPS562555A (en) 1981-01-12
JPS6022295B2 JPS6022295B2 (en) 1985-06-01

Family

ID=13688061

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7937379A Expired JPS6022295B2 (en) 1979-06-22 1979-06-22 Aqueous solvent for red blood cell agglutination test

Country Status (1)

Country Link
JP (1) JPS6022295B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59102161A (en) * 1982-12-03 1984-06-13 Chemo Sero Therapeut Res Inst Antigen detection reagent by anti-passive agglutination
ES2141684A1 (en) * 1998-07-15 2000-03-16 Univ Granada Reaction buffer for stabilising latex-IgG particles for an immunoaglutination test
JP2008249738A (en) * 2008-07-18 2008-10-16 Eiken Chem Co Ltd Method for removing immunoreaction interfering substance
JP2019078767A (en) * 2012-12-05 2019-05-23 コニカミノルタ株式会社 Method of suppressing nonspecific signals originating from contaminants in immunoassay using surface plasmon excitation enhanced fluorescence spectroscopy (spfs)
WO2023190003A1 (en) * 2022-03-29 2023-10-05 ミナリスメディカル株式会社 Method for measuring sialyl-lewis antigen, reagent for measurement, and kit for measurement

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104634966A (en) * 2010-03-31 2015-05-20 积水医疗株式会社 Method for avoiding influence of endogenous lipoprotein and reagent

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59102161A (en) * 1982-12-03 1984-06-13 Chemo Sero Therapeut Res Inst Antigen detection reagent by anti-passive agglutination
JPH0230667B2 (en) * 1982-12-03 1990-07-09 Kagaku Oyobi Ketsusei Ryoho Kenkyusho
ES2141684A1 (en) * 1998-07-15 2000-03-16 Univ Granada Reaction buffer for stabilising latex-IgG particles for an immunoaglutination test
JP2008249738A (en) * 2008-07-18 2008-10-16 Eiken Chem Co Ltd Method for removing immunoreaction interfering substance
JP4657328B2 (en) * 2008-07-18 2011-03-23 栄研化学株式会社 Methods for removing immune reaction interfering substances
JP2019078767A (en) * 2012-12-05 2019-05-23 コニカミノルタ株式会社 Method of suppressing nonspecific signals originating from contaminants in immunoassay using surface plasmon excitation enhanced fluorescence spectroscopy (spfs)
US11162940B2 (en) 2012-12-05 2021-11-02 Konica Minolta, Inc. Method for suppressing nonspecific signals from contaminants in an immunoassay using surface plasmon-field enhanced fluorescence spectroscopy (SPFS)
WO2023190003A1 (en) * 2022-03-29 2023-10-05 ミナリスメディカル株式会社 Method for measuring sialyl-lewis antigen, reagent for measurement, and kit for measurement

Also Published As

Publication number Publication date
JPS6022295B2 (en) 1985-06-01

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