JPS5624664B2 - - Google Patents

Info

Publication number
JPS5624664B2
JPS5624664B2 JP7340573A JP7340573A JPS5624664B2 JP S5624664 B2 JPS5624664 B2 JP S5624664B2 JP 7340573 A JP7340573 A JP 7340573A JP 7340573 A JP7340573 A JP 7340573A JP S5624664 B2 JPS5624664 B2 JP S5624664B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP7340573A
Other languages
Japanese (ja)
Other versions
JPS5024216A (US20110009641A1-20110113-C00179.png
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP7340573A priority Critical patent/JPS5624664B2/ja
Priority to IT2444874A priority patent/IT1015418B/it
Priority to DE19742430998 priority patent/DE2430998A1/de
Priority to FR7422691A priority patent/FR2235112A1/fr
Priority to NL7408784A priority patent/NL7408784A/xx
Publication of JPS5024216A publication Critical patent/JPS5024216A/ja
Publication of JPS5624664B2 publication Critical patent/JPS5624664B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/16Nitrogen-containing compounds
    • C08K5/20Carboxylic acid amides
JP7340573A 1973-06-28 1973-06-28 Expired JPS5624664B2 (US20110009641A1-20110113-C00179.png)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP7340573A JPS5624664B2 (US20110009641A1-20110113-C00179.png) 1973-06-28 1973-06-28
IT2444874A IT1015418B (it) 1973-06-28 1974-06-25 Composti organici e procedimento per la loro preparazione
DE19742430998 DE2430998A1 (de) 1973-06-28 1974-06-27 Neue organische verbindungen mit einer n,n-dialkylsubstibuierten amidgruppe und verfahren zu deren herstellung
FR7422691A FR2235112A1 (en) 1973-06-28 1974-06-28 Cpds contg dialkyl-substd amide gps - used as surfactants, dispersants, solvents, chelating agents and polymer modifiers
NL7408784A NL7408784A (US20110009641A1-20110113-C00179.png) 1973-06-28 1974-06-28

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7340573A JPS5624664B2 (US20110009641A1-20110113-C00179.png) 1973-06-28 1973-06-28

Publications (2)

Publication Number Publication Date
JPS5024216A JPS5024216A (US20110009641A1-20110113-C00179.png) 1975-03-15
JPS5624664B2 true JPS5624664B2 (US20110009641A1-20110113-C00179.png) 1981-06-08

Family

ID=13517239

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7340573A Expired JPS5624664B2 (US20110009641A1-20110113-C00179.png) 1973-06-28 1973-06-28

Country Status (5)

Country Link
JP (1) JPS5624664B2 (US20110009641A1-20110113-C00179.png)
DE (1) DE2430998A1 (US20110009641A1-20110113-C00179.png)
FR (1) FR2235112A1 (US20110009641A1-20110113-C00179.png)
IT (1) IT1015418B (US20110009641A1-20110113-C00179.png)
NL (1) NL7408784A (US20110009641A1-20110113-C00179.png)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5524563A (en) * 1978-08-09 1980-02-21 Nitto Electric Ind Co Ltd Tubular membrane separating module
CN101346468B (zh) * 2005-06-15 2016-03-30 麻省理工学院 含胺脂质和其用途
AU2009311667B2 (en) 2008-11-07 2016-04-14 Massachusetts Institute Of Technology Aminoalcohol lipidoids and uses thereof
NZ600616A (en) 2009-12-01 2014-11-28 Shire Human Genetic Therapies Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
DK2691443T3 (da) 2011-03-28 2021-05-03 Massachusetts Inst Technology Konjugerede lipomerer og anvendelser af disse
EP4043025A1 (en) 2011-06-08 2022-08-17 Translate Bio, Inc. Lipid nanoparticle compositions and methods for mrna delivery
US20150267192A1 (en) 2012-06-08 2015-09-24 Shire Human Genetic Therapies, Inc. Nuclease resistant polynucleotides and uses thereof
WO2014028487A1 (en) 2012-08-13 2014-02-20 Massachusetts Institute Of Technology Amine-containing lipidoids and uses thereof
PE20151773A1 (es) 2013-03-14 2015-12-20 Shire Human Genetic Therapies COMPOSICIONES DE ARNm DE CFTR, METODOS Y USOS RELACIONADOS
ES2708561T3 (es) 2013-03-14 2019-04-10 Translate Bio Inc Métodos para la purificación de ARN mensajero
US9315472B2 (en) 2013-05-01 2016-04-19 Massachusetts Institute Of Technology 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
EP3060257B1 (en) 2013-10-22 2021-02-24 Translate Bio, Inc. Lipid formulations for delivery of messenger rna
MX2016005239A (es) 2013-10-22 2016-08-12 Shire Human Genetic Therapies Tratamiento con acido ribonucleico mensajero para la fenilcetonuria.
EP4276176A3 (en) 2013-10-22 2024-01-10 Translate Bio, Inc. Mrna therapy for argininosuccinate synthetase deficiency
KR20220158867A (ko) 2014-04-25 2022-12-01 샤이어 휴먼 지네틱 테라피즈 인크. 메신저 rna 의 정제 방법
JP6557722B2 (ja) 2014-05-30 2019-08-07 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド 核酸の送達のための生分解性脂質
WO2015200465A1 (en) 2014-06-24 2015-12-30 Shire Human Genetic Therapies, Inc. Stereochemically enriched compositions for delivery of nucleic acids
WO2016004202A1 (en) 2014-07-02 2016-01-07 Massachusetts Institute Of Technology Polyamine-fatty acid derived lipidoids and uses thereof
AU2018224326B2 (en) 2017-02-27 2024-01-04 Translate Bio, Inc. Novel codon-optimized CFTR mRNA
US11173190B2 (en) 2017-05-16 2021-11-16 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of codon-optimized mRNA encoding CFTR
AU2019325702A1 (en) 2018-08-24 2021-02-25 Translate Bio, Inc. Methods for purification of messenger RNA

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2372808A (en) * 1941-07-30 1945-04-03 Resinous Prod & Chemical Co Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2372808A (en) * 1941-07-30 1945-04-03 Resinous Prod & Chemical Co Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols

Also Published As

Publication number Publication date
IT1015418B (it) 1977-05-10
NL7408784A (US20110009641A1-20110113-C00179.png) 1974-12-31
DE2430998A1 (de) 1975-01-09
JPS5024216A (US20110009641A1-20110113-C00179.png) 1975-03-15
FR2235112A1 (en) 1975-01-24

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