JPS5618919A - Thrombolytic agent - Google Patents
Thrombolytic agentInfo
- Publication number
- JPS5618919A JPS5618919A JP9472479A JP9472479A JPS5618919A JP S5618919 A JPS5618919 A JP S5618919A JP 9472479 A JP9472479 A JP 9472479A JP 9472479 A JP9472479 A JP 9472479A JP S5618919 A JPS5618919 A JP S5618919A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- effective component
- formula
- lower alkyl
- thrombolytic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: An inexpensive and stable thrombolytic agent that contains a specific bis-trimethoxybenzoate as the effective component.
CONSTITUTION: Said agent contains a compound of the formula (R is H, lower alkyl, lower acyl; R1 is H, lower alkyl, two R1s may incorporate to form lower alkylene; A is straight or branched alkylene; n is 2 or 3) such as 3,3'-[ethylenebis- (methylamino)]di-1-propanol 3,4,5-timethoxybenzoate dihydrochloride as the effective component. The compound of the formula accelerates the decomposition of fibrin (fibrinolysis) by liberation of tissue activator to activate plasminogen and block plasminogen inhibitor. It has lower molecular weight and higher stability than urokinase and streptokinase and shows low acute toxicity and little side-effects.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9472479A JPS5618919A (en) | 1979-07-25 | 1979-07-25 | Thrombolytic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9472479A JPS5618919A (en) | 1979-07-25 | 1979-07-25 | Thrombolytic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5618919A true JPS5618919A (en) | 1981-02-23 |
JPS6357404B2 JPS6357404B2 (en) | 1988-11-11 |
Family
ID=14118059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9472479A Granted JPS5618919A (en) | 1979-07-25 | 1979-07-25 | Thrombolytic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5618919A (en) |
-
1979
- 1979-07-25 JP JP9472479A patent/JPS5618919A/en active Granted
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS=1975 * |
Also Published As
Publication number | Publication date |
---|---|
JPS6357404B2 (en) | 1988-11-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5262213A (en) | Polypluenyl derivatives | |
JPS5297950A (en) | Chalconeether derivatives | |
JPS5395977A (en) | 1,4-dihydropyrimidine compounds and process for their preparation | |
ES2098961T3 (en) | ULTRA-SOFT MIXING OF SURFACTANTS. | |
EP0645382A4 (en) | Coumarin derivative and use thereof. | |
JPS5439040A (en) | Novel 2-hydroxybenzamide derivatives and bactericides for the soil | |
JPS56156242A (en) | Quaternary ammonium compound containing fluorine and its preparation | |
JPS5618919A (en) | Thrombolytic agent | |
JPS5692217A (en) | Easily absorbable enzyme preparation | |
JPS5398954A (en) | L-ascorbic acid derivatives | |
NO944309L (en) | Process for the preparation of ribonucleotide reductase inhibitors | |
JPS5234922A (en) | Novel antimicrobial agent for non-medical use | |
JPS5359674A (en) | 1-piperidinoalkane-1,1-diphosphonic acid derivatives and herbicidescontaining the same as active agent | |
JPS52122358A (en) | Novel methano-anthracene derivatives | |
EP0569598A4 (en) | ||
JPS5765761A (en) | Antistatic, acting ray-curable coat composition | |
JPS548627A (en) | 2-alkoxyalkoxy-5-nitrobenzenesulfonic acid and its salt | |
JPS5425287A (en) | Foam breaking agent | |
JPS5721360A (en) | Allyl 4-guanidinomethylcyclohexanecarboxylate and its preparation | |
JPS5287138A (en) | Optically active ester | |
JPS53102985A (en) | Cyclodextrin derivative and its produdtion | |
JPS5353652A (en) | Novel imidazole derivatives | |
JPS5293799A (en) | Recerpine derivatives and antiarryhythics | |
JPS5692213A (en) | Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredient | |
JPS5283678A (en) | Adamantane derivative and cerebral vasodilator containing same |