JPS56137897A - Production of desalanine- b30 -insulin - Google Patents

Production of desalanine- b30 -insulin

Info

Publication number
JPS56137897A
JPS56137897A JP4059480A JP4059480A JPS56137897A JP S56137897 A JPS56137897 A JP S56137897A JP 4059480 A JP4059480 A JP 4059480A JP 4059480 A JP4059480 A JP 4059480A JP S56137897 A JPS56137897 A JP S56137897A
Authority
JP
Japan
Prior art keywords
insulin
nitroanilide
hydrolase
arginine
benzoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4059480A
Other languages
Japanese (ja)
Inventor
Etsushirou Doi
Kazuyuki Morihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP4059480A priority Critical patent/JPS56137897A/en
Publication of JPS56137897A publication Critical patent/JPS56137897A/en
Pending legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: A hydrolase for benzoyl-L-arginine-p-nitroanilide, originated from a plant, is made to act on insulin originating from other than human to permit the production of the titled compound from an available raw material.
CONSTITUTION: A hydrolase for benzoyl-L-arginine-p-nitroanilide, originating from a plant, is made to act on insulin obtained from an animal other than human such as pig, cattle, sheep or horse. The hydrolase for benzoyl-L-arginine-p-nitroanilide has been known to exist in rice germ, soybean or barley and can be extracted from rice germ through known processes. The above reaction gives desalanine-(B-30)- insulin, which is used as a raw material for human insulin.
COPYRIGHT: (C)1981,JPO&Japio
JP4059480A 1980-03-28 1980-03-28 Production of desalanine- b30 -insulin Pending JPS56137897A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4059480A JPS56137897A (en) 1980-03-28 1980-03-28 Production of desalanine- b30 -insulin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4059480A JPS56137897A (en) 1980-03-28 1980-03-28 Production of desalanine- b30 -insulin

Publications (1)

Publication Number Publication Date
JPS56137897A true JPS56137897A (en) 1981-10-28

Family

ID=12584825

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4059480A Pending JPS56137897A (en) 1980-03-28 1980-03-28 Production of desalanine- b30 -insulin

Country Status (1)

Country Link
JP (1) JPS56137897A (en)

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