JPS56117794A - Preparation of coenzyme q by solid cultivation - Google Patents

Preparation of coenzyme q by solid cultivation

Info

Publication number
JPS56117794A
JPS56117794A JP1854180A JP1854180A JPS56117794A JP S56117794 A JPS56117794 A JP S56117794A JP 1854180 A JP1854180 A JP 1854180A JP 1854180 A JP1854180 A JP 1854180A JP S56117794 A JPS56117794 A JP S56117794A
Authority
JP
Japan
Prior art keywords
coenzyme
medium
subjected
solid
fungus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1854180A
Other languages
Japanese (ja)
Inventor
Tamio Mase
Masaaki Yokoe
Kuniyoshi Matsunaga
Yoshimasa Takagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amano Enzyme Inc
Original Assignee
Amano Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amano Pharmaceutical Co Ltd filed Critical Amano Pharmaceutical Co Ltd
Priority to JP1854180A priority Critical patent/JPS56117794A/en
Publication of JPS56117794A publication Critical patent/JPS56117794A/en
Pending legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare coenzyme q in high efficiency, by cultivating a coenzyme Q producing fungus, e.g., Paecilomyces varioti, in a solid medium, collecting coenzyme Q from the culture conventionally.
CONSTITUTION: A coenzyme-producing fungus, e.g., Paecilomyces varioti No.9215, Asperigillus clavatus IAM2041, etc. is cultivated in a solid medium comprising wheat, rice, corn, crushed grain, and, if necessary, blended with yeast extract, an organic substance, e.g., extract from soybean, etc., an inorganic salt, e.g., ammonium slat, nitrate, etc., and vitamin, etc. Water is sprinkled on the medium and it is boiled and steamed. A seed fungus is inoculated on the medium and settled or aerated cultivation is carried out. A mixture of methanol, pyrogallol, and sodium hydroxide is added to the solid culture, which is subjected to saponification and extraction. A coenzyme shown by the formula is extracted from the saponified solution with n-hexane. The coenzyme is subjected to fractional, purification by a column, crystallized from ethanol and isolated.
COPYRIGHT: (C)1981,JPO&Japio
JP1854180A 1980-02-19 1980-02-19 Preparation of coenzyme q by solid cultivation Pending JPS56117794A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1854180A JPS56117794A (en) 1980-02-19 1980-02-19 Preparation of coenzyme q by solid cultivation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1854180A JPS56117794A (en) 1980-02-19 1980-02-19 Preparation of coenzyme q by solid cultivation

Publications (1)

Publication Number Publication Date
JPS56117794A true JPS56117794A (en) 1981-09-16

Family

ID=11974483

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1854180A Pending JPS56117794A (en) 1980-02-19 1980-02-19 Preparation of coenzyme q by solid cultivation

Country Status (1)

Country Link
JP (1) JPS56117794A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1873235A1 (en) * 2006-06-26 2008-01-02 Universita' degli Studi di Milano A method for the preparation of Penicillium spores and the use of the latter in the food field

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1873235A1 (en) * 2006-06-26 2008-01-02 Universita' degli Studi di Milano A method for the preparation of Penicillium spores and the use of the latter in the food field

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