JPS56108789A - 2-azaerythrinane derivative - Google Patents

2-azaerythrinane derivative

Info

Publication number
JPS56108789A
JPS56108789A JP917580A JP917580A JPS56108789A JP S56108789 A JPS56108789 A JP S56108789A JP 917580 A JP917580 A JP 917580A JP 917580 A JP917580 A JP 917580A JP S56108789 A JPS56108789 A JP S56108789A
Authority
JP
Japan
Prior art keywords
formula
compound
benzyl
azaerythrinane
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP917580A
Other languages
Japanese (ja)
Other versions
JPS6043350B2 (en
Inventor
Hiroshi Murai
Shingo Matsumura
Iwao Morita
Mitsuhiro Maehara
Kenji Kazuno
Hiroshi Enomoto
Kiyoshi Kimura
Yutaka Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP55009175A priority Critical patent/JPS6043350B2/en
Publication of JPS56108789A publication Critical patent/JPS56108789A/en
Publication of JPS6043350B2 publication Critical patent/JPS6043350B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (Y is O, S, NH, NCH3., etc.; n is 1 or 2; R1, R2 and R3 are H, lower alkyl, halogen, etc.; R4 is H, lower alkyl, lower alkoxycarbonyl, etc.; the dotted line is unsaturated bond or saturated bond), its acid addition salt, and their optically active isomers. EXAMPLE:2-Benzyl-8-oxo-2-azaerythrinane. USE:An analgesic agent having central nervous system depressing activity. PROCESS:The compound of formula I is prepared by the thermal condensation of a 4-piperidone compound of formula II (R9 is benzyl, phenetyl, methyl, etc.; R10 is ethyl; n is 1 or 2) with an amine of formula III in a solvent such as benzene, toluene, etc., followed by the ring-closing reaction under acidic conditions.
JP55009175A 1980-01-28 1980-01-28 2-Azaerythrinane derivative Expired JPS6043350B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55009175A JPS6043350B2 (en) 1980-01-28 1980-01-28 2-Azaerythrinane derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55009175A JPS6043350B2 (en) 1980-01-28 1980-01-28 2-Azaerythrinane derivative

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP60057038A Division JPS60214789A (en) 1985-03-19 1985-03-19 2-azaerythrinan derivative

Publications (2)

Publication Number Publication Date
JPS56108789A true JPS56108789A (en) 1981-08-28
JPS6043350B2 JPS6043350B2 (en) 1985-09-27

Family

ID=11713229

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55009175A Expired JPS6043350B2 (en) 1980-01-28 1980-01-28 2-Azaerythrinane derivative

Country Status (1)

Country Link
JP (1) JPS6043350B2 (en)

Also Published As

Publication number Publication date
JPS6043350B2 (en) 1985-09-27

Similar Documents

Publication Publication Date Title
UA8022A1 (en) Process for the preparation of benzimidazole derivatives as isomeric mixture or individual isomers in free state , or as pharmaceutically acceptable salts thereof
FI906438A0 (en) Process for the preparation of new therapeutically useful A-nor-steroid-3-carboxylic acid derivatives
DK0657428T3 (en) Preparation of 3,4,4-trisubstituted-piperidinyl-N-alkylcarboxylates and intermediates useful as opioid antagonists
ES8502106A1 (en) Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals.
ES2083954T3 (en) PROCESS FOR THE PREPARATION OF CAST PIRIDINE COMPOUNDS.
EP0220865A3 (en) Lactam derivatives, their preparation and their use as hypotensive agents
JPS56108789A (en) 2-azaerythrinane derivative
DK466786A (en) PROCEDURE FOR THE PREPARATION OF N-SUBSTITUTED DIHYDROLYRIC ACID DERIVATIVES
ES2104688T3 (en) A PROCEDURE FOR THE PREPARATION OF A TIO-3-CEFEM 3-SUBSTITUTED COMPOUND.
JPS5583749A (en) Quinolone derivative
TW339325B (en) Novel azepane derivatives, process for the preparation thereof and pharmaceutical composition containing the same
SE7704088L (en) WAY TO PREPARE DIPEPTI DERIVATIVES
ES2042850T3 (en) NEW PROCEDURE FOR THE PREPARATION OF OXALIL- AND OXAMIL-HYDRACIDES.
JPS5585550A (en) 4-homoisotwistane amino acid amide
AR241137A2 (en) Novel allylic amines
CA2005596A1 (en) Preparation of 2-amino-4-fluoropyrimidine derivatives
ES2080891T3 (en) PREPARATION OF OPTICALLY ACTIVE NORBORNIL AMINE DERIVATIVES.
JPS572266A (en) Novel benzamide derivative
EP0119540A3 (en) Substituted alkylamine derivatives of 6,11-dihydro-11-oxodibenz (b,e)-oxepins, a process for the preparation and intermediates thereof and their use as medicaments
HU913759D0 (en) Process for the production of indole compounds
PT84517B (en) PREPARED PROCESS FOR THE PREPARATION OF DIHYDRO-1H-PYRROLIZINE 3,5- (2H, 6H) -BIONA
JPS552643A (en) Preparation of n-methyl-benzthiazolone derivative
JPS56161362A (en) Anthranilic acid derivative
JPS6419063A (en) Novel heterocyclic compound and use thereof
JPS56113785A (en) 2-azaerythrinan derivative