JPS559738A - Production of optically active 3-hydroxy-4- (hydroxymethyl)phenylglycine - Google Patents

Production of optically active 3-hydroxy-4- (hydroxymethyl)phenylglycine

Info

Publication number
JPS559738A
JPS559738A JP8195478A JP8195478A JPS559738A JP S559738 A JPS559738 A JP S559738A JP 8195478 A JP8195478 A JP 8195478A JP 8195478 A JP8195478 A JP 8195478A JP S559738 A JPS559738 A JP S559738A
Authority
JP
Japan
Prior art keywords
phenylglycine
hydroxymethyl
hydroxy
optically active
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8195478A
Other languages
Japanese (ja)
Other versions
JPS6225359B2 (en
Inventor
Hamao Umezawa
Hajime Morishima
Ryosuke Ushijima
Junji Yoshizawa
Hideo Takeda
Ikuo Iwatsuki
Ikuo Matsumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Priority to JP8195478A priority Critical patent/JPS559738A/en
Publication of JPS559738A publication Critical patent/JPS559738A/en
Publication of JPS6225359B2 publication Critical patent/JPS6225359B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: An aminoacylase originating from microorganism is made to act on an N- acylaminoacid to effect the asymmetric hydrolysis, thus producing optically active 3-hydroxy-4-(hydroxymethyl)phenylglycine.
CONSTITUTION: An aminacylase originating from microorganism as from molds or Azotobacter is made to act on N-acetyl or N-benzoyl-3-hydroxy-4-(hydroxymethyl)-DL-phenylglycine to effect the asymmetric hydrolysis. 3-Hydroxy-4-(hydroxymethyl)-L-phenylglycine and N-acetyl- or N-benzoly-3-hydroxy-4-(hydroxymethyl)-D-phenylglycine are adsorbed on a strongly acidic ion exchange resin from the reaction mixture, then isolated.
COPYRIGHT: (C)1980,JPO&Japio
JP8195478A 1978-07-07 1978-07-07 Production of optically active 3-hydroxy-4- (hydroxymethyl)phenylglycine Granted JPS559738A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8195478A JPS559738A (en) 1978-07-07 1978-07-07 Production of optically active 3-hydroxy-4- (hydroxymethyl)phenylglycine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8195478A JPS559738A (en) 1978-07-07 1978-07-07 Production of optically active 3-hydroxy-4- (hydroxymethyl)phenylglycine

Publications (2)

Publication Number Publication Date
JPS559738A true JPS559738A (en) 1980-01-23
JPS6225359B2 JPS6225359B2 (en) 1987-06-02

Family

ID=13760885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8195478A Granted JPS559738A (en) 1978-07-07 1978-07-07 Production of optically active 3-hydroxy-4- (hydroxymethyl)phenylglycine

Country Status (1)

Country Link
JP (1) JPS559738A (en)

Also Published As

Publication number Publication date
JPS6225359B2 (en) 1987-06-02

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