JPS5583714A - Isolation of hepatitis be antigen - Google Patents

Isolation of hepatitis be antigen

Info

Publication number
JPS5583714A
JPS5583714A JP16215579A JP16215579A JPS5583714A JP S5583714 A JPS5583714 A JP S5583714A JP 16215579 A JP16215579 A JP 16215579A JP 16215579 A JP16215579 A JP 16215579A JP S5583714 A JPS5583714 A JP S5583714A
Authority
JP
Japan
Prior art keywords
hepatitis
antigen
isolation
centrifugation
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16215579A
Other languages
English (en)
Other versions
JPS6361624B2 (ja
Inventor
Jiee Makuaree Uiriamu
Etsuchi Wasumusu Edowaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5583714A publication Critical patent/JPS5583714A/ja
Publication of JPS6361624B2 publication Critical patent/JPS6361624B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP16215579A 1978-12-13 1979-12-13 Isolation of hepatitis be antigen Granted JPS5583714A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/968,896 US4204989A (en) 1978-12-13 1978-12-13 Isolation of hepatitis B e antigen

Publications (2)

Publication Number Publication Date
JPS5583714A true JPS5583714A (en) 1980-06-24
JPS6361624B2 JPS6361624B2 (ja) 1988-11-29

Family

ID=25514908

Family Applications (2)

Application Number Title Priority Date Filing Date
JP16215579A Granted JPS5583714A (en) 1978-12-13 1979-12-13 Isolation of hepatitis be antigen
JP63065867A Granted JPS63264499A (ja) 1978-12-13 1988-03-22 肝炎Ｂｅ抗体の単離法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP63065867A Granted JPS63264499A (ja) 1978-12-13 1988-03-22 肝炎Ｂｅ抗体の単離法

Country Status (8)

Country Link
US (1) US4204989A (ja)
EP (1) EP0012686B1 (ja)
JP (2) JPS5583714A (ja)
AT (1) ATE2048T1 (ja)
CA (1) CA1129768A (ja)
DE (1) DE2964390D1 (ja)
DK (1) DK528279A (ja)
IE (1) IE48665B1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus
US4349539A (en) * 1980-08-15 1982-09-14 Merck & Co., Inc. Separation of hepatitis B surface antigen
JPH0625069B2 (ja) * 1981-01-29 1994-04-06 ブリティッシュ・テクノロジー・グループ・リミテッド Ｂ型肝炎ワクチン製造方法
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
CA1232849A (en) * 1983-12-01 1988-02-16 The Washington University Circulating antigens of dirofilaria immitis, monoclonal antibodies specific therefor and methods of preparing such antibodies and detecting such antigens
US5101018A (en) * 1989-06-12 1992-03-31 International Minerals & Chemical Corp. Method for recovering recombinant proteins
US5047511A (en) * 1989-08-28 1991-09-10 Pitman-Moore, Inc. Method for recovering recombinant proteins
JPH0660773U (ja) * 1993-01-25 1994-08-23 株式会社中川水力 電動サ−ボモ−タ方式電気調速機

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
US3887697A (en) * 1971-08-09 1975-06-03 Us Health Hemagglutination method for australia antigen and antibody thereto
GB1356413A (en) * 1971-09-09 1974-06-12 Pfizer Ltd Method of obtaining purified australia antigen from blood serum
US3994870A (en) * 1974-01-31 1976-11-30 The Community Blood Council Of Greater New York, Inc. Purification of hepatitis B surface antigen
US3992517A (en) * 1975-02-19 1976-11-16 Pfizer Inc. Detection of hepatitis B surface antigen by latex agglutination
US4024243A (en) * 1975-06-16 1977-05-17 Merck & Co., Inc. Process for isolating hepatitis B antigen
FR2336141A1 (fr) * 1975-12-23 1977-07-22 Trepo Christian Nouveau medicament permettant de traiter les infections aigues ou chroniques dues au virus de l'hepatite b
US4088748A (en) * 1976-11-02 1978-05-09 Merck & Co., Inc. Hepatitis B surface antigen
US4118477A (en) * 1977-02-14 1978-10-03 Merck & Co., Inc. Hepatitis B antigen
US4102996A (en) * 1977-04-20 1978-07-25 Merck & Co., Inc. Method of preparing hepatitis B core antigen

Also Published As

Publication number Publication date
DE2964390D1 (en) 1983-01-27
EP0012686B1 (en) 1982-12-22
EP0012686A1 (en) 1980-06-25
JPH0240987B2 (ja) 1990-09-14
CA1129768A (en) 1982-08-17
JPS63264499A (ja) 1988-11-01
ATE2048T1 (de) 1983-01-15
IE48665B1 (en) 1985-04-03
JPS6361624B2 (ja) 1988-11-29
DK528279A (da) 1980-06-14
US4204989A (en) 1980-05-27
IE792390L (en) 1980-06-13

Similar Documents

Publication Publication Date Title
JPS5786051A (en) Determination of antigen employing two or more monochronal antibodies
NO165598C (no) Fremgangsmaate for ekspresjon av hepatitt b overflateantigen i cellekultur samt ekspresjonsvektor.
GB2102810B (en) Human interferon-related peptides antigens antibodies and process for preparing the same
DE2963977D1 (en) Antigen preparation, process for producing it and pharmacological or dental preparations containing the antigen preparation or antibodies thereto
GB2015156B (en) Determination of antigens of antibodies
DE3175955D1 (en) Process for the deternination of antigens or antibodies
AU525403B2 (en) Purified antigen
DE2964390D1 (en) Isolation of hepatitis be antigen
PT72301A (en) Process for the detection of human cancer cells with antibodies to human cancer nucleolar antigens
EP0131627A4 (en) SPECIFIC ANTIGENS OF THE CEA FAMILY (CARCINO-EMBRYONIC ANTIGEN), SPECIFIC ANTIBODIES OF THESE ANTIGENS AND THEIR METHODS OF USE.
JPS5396316A (en) Analysis of antigen * antibody or antigenn antibody complex in liquid
GB2018258A (en) 3 acetoxy & 11 epoxy pregna 3,5 dienes and 1,3,5 trienes and their use in the synthesis of 6 halocorticoids
DE69133185D1 (de) Entwicklung von dns-sonden und immunologischen reagenzien von menschlichen tumor-assoziierten antigenen
DK21586D0 (da) Antigener og antistoffer samt praeparater indeholdende disse
ZA805898B (en) Assay for the free portion of substances in biological fluids
DE3066975D1 (en) Propranolol antigen conjugates and antibodies and method of using them
JPS56154931A (en) Culture medium of "matsutake" mycelium
JPS5677758A (en) Method of classifying blood and antibody reagent
JPS57156560A (en) Determination of antigen or antibody
IT8121549A0 (it) Metodo integrato per l'analisi degli anticorpi antistreptolisinici e mezzi adatti allo scopo.
IL59310A (en) Determination of malaria antigens and antibodies
IT7833801V0 (it) Accoppiamenti metallo - pellame per la realizzazione di decorazioni nel le calzature e borse in genere
IL60664A0 (en) Monoclonal antibodies and assay for the detection of breast cancer
ZA831050B (en) Antibodies and antigens useful in the diagnosis and treatment of cancer
ZW4783A1 (en) Antibodies and antigens useful in the diagnosis and treatment of cancer