JPS5578001A - Polysaccharide-polypeptide combination having beta(1-3), (1-6) glucan structure and its preparation - Google Patents
Polysaccharide-polypeptide combination having beta(1-3), (1-6) glucan structure and its preparationInfo
- Publication number
- JPS5578001A JPS5578001A JP15127578A JP15127578A JPS5578001A JP S5578001 A JPS5578001 A JP S5578001A JP 15127578 A JP15127578 A JP 15127578A JP 15127578 A JP15127578 A JP 15127578A JP S5578001 A JPS5578001 A JP S5578001A
- Authority
- JP
- Japan
- Prior art keywords
- polysaccharide
- polypeptide
- reacted
- reaction product
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
PURPOSE: To obtain the title novel compound useful as oral antitumor, liver function improving, antidepressive, and antihyperlipemia drugs, by reacting the reaction product between a specific polysaccharide and a cyanogen halide with a polypeptide.
CONSTITUTION: The hydroxyl group in the side chain or cleaved terminal glucose ring of the (1-6) bond in (A) a polysaccharide, D-11 of the formula I or its derivative, obtained from mycelia is reacted with (B) a cyanogen halide or perhalogenate. (C) A polypeptide having terminal amino groups, e.g. bovine serum albumin, is reacted with the reaction product thus obtained to give the objective compound. The component (A) is preferably prepared by extracting and purifying a cultured mycelia of Ceriolus Versicolor IWADE.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15127578A JPS5578001A (en) | 1978-12-06 | 1978-12-06 | Polysaccharide-polypeptide combination having beta(1-3), (1-6) glucan structure and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15127578A JPS5578001A (en) | 1978-12-06 | 1978-12-06 | Polysaccharide-polypeptide combination having beta(1-3), (1-6) glucan structure and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5578001A true JPS5578001A (en) | 1980-06-12 |
Family
ID=15515107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15127578A Pending JPS5578001A (en) | 1978-12-06 | 1978-12-06 | Polysaccharide-polypeptide combination having beta(1-3), (1-6) glucan structure and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5578001A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2314850A (en) * | 1995-03-13 | 1998-01-14 | Norvet Research Pty Ltd | Process for glucan preparation and therapeutic uses of glucan |
KR100563616B1 (en) * | 2004-05-20 | 2006-03-22 | 그린텍이십일 주식회사 | ?-Glucan derivative, manufacture of the derivative, adhesion Barrier using ?-glucan and method thereof |
CN106323895A (en) * | 2016-08-22 | 2017-01-11 | 宁波希诺亚海洋生物科技有限公司 | Structural analysis method of beta-glucan |
-
1978
- 1978-12-06 JP JP15127578A patent/JPS5578001A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2314850A (en) * | 1995-03-13 | 1998-01-14 | Norvet Research Pty Ltd | Process for glucan preparation and therapeutic uses of glucan |
GB2314850B (en) * | 1995-03-13 | 1999-07-14 | Norvet Research Pty Ltd | Process for glucan preparation |
US7622575B2 (en) | 1995-03-13 | 2009-11-24 | Novogen Research Pty. Ltd. | Therapeutic uses of glucan |
US7648968B2 (en) | 1995-03-13 | 2010-01-19 | Novogen Research Pty. Ltd. | Methods of treating dermal ulcers using glucans |
US7776843B2 (en) | 1995-03-13 | 2010-08-17 | Novogen Research Pty. Ltd. | Therapeutic uses of glucan |
KR100563616B1 (en) * | 2004-05-20 | 2006-03-22 | 그린텍이십일 주식회사 | ?-Glucan derivative, manufacture of the derivative, adhesion Barrier using ?-glucan and method thereof |
CN106323895A (en) * | 2016-08-22 | 2017-01-11 | 宁波希诺亚海洋生物科技有限公司 | Structural analysis method of beta-glucan |
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