JPS5576874A - Novel antibiotic a40a and its preparation - Google Patents

Novel antibiotic a40a and its preparation

Info

Publication number
JPS5576874A
JPS5576874A JP13859579A JP13859579A JPS5576874A JP S5576874 A JPS5576874 A JP S5576874A JP 13859579 A JP13859579 A JP 13859579A JP 13859579 A JP13859579 A JP 13859579A JP S5576874 A JPS5576874 A JP S5576874A
Authority
JP
Japan
Prior art keywords
solvent
eluted
carbon atom
organic solvent
polar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13859579A
Other languages
Japanese (ja)
Other versions
JPS6221790B2 (en
Inventor
Esu Deyuii Rei
Pii Guaroo Buinsento
Bii Jinmeruman Shierudon
Satoshi Omura
Ruiko Oiwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Publication of JPS5576874A publication Critical patent/JPS5576874A/en
Publication of JPS6221790B2 publication Critical patent/JPS6221790B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound A40A of the formula (the configuration of the pyran is S at the hemiketal 2, S at the carbon atom 4 having an OH group, and S at the carbon atom 6 having the pentadienyl side chain), its salt or ester.
USE: Antibiotics effective against Gram-positive and limited Gram-negative bacteria, and growth accelerators for animals.
PROCESS: Strains of Streptomyces lavendulae MA-4758(ATCC 31312) are cultured aerobically in an aqueous nutrient medium containing assimilable carbon and nitrogen sources, at 20W37°C, preferably 24W32°C and a pH of 6.0W8.0. After culturing, the broth is filtered, and the objective substance is adsorbed on an adequate resin, and eluted. The eluted concentrate is extracted with a water-immiscible organic solvent to take out the solvent layer. The solvent is then evaporated, and the residue is redissolved in a polar organic solvent, e.g. ethyl acetate, and then precipitated with a non-polar solvent, to give the antibiotic A40A.
COPYRIGHT: (C)1980,JPO&Japio
JP13859579A 1978-10-27 1979-10-26 Novel antibiotic a40a and its preparation Granted JPS5576874A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95555378A 1978-10-27 1978-10-27

Publications (2)

Publication Number Publication Date
JPS5576874A true JPS5576874A (en) 1980-06-10
JPS6221790B2 JPS6221790B2 (en) 1987-05-14

Family

ID=25496986

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13859579A Granted JPS5576874A (en) 1978-10-27 1979-10-26 Novel antibiotic a40a and its preparation

Country Status (1)

Country Link
JP (1) JPS5576874A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0565529A (en) * 1992-02-28 1993-03-19 Asahi Glass Co Ltd Skid rail complexing ceramics
ES2164536A1 (en) * 1999-06-30 2002-02-16 Univ Salamanca Isolation and growth of bacteria using mannitol as a carbon source consists of rhizobiaceae bacteria production from a suspension, for sample analysis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0565529A (en) * 1992-02-28 1993-03-19 Asahi Glass Co Ltd Skid rail complexing ceramics
ES2164536A1 (en) * 1999-06-30 2002-02-16 Univ Salamanca Isolation and growth of bacteria using mannitol as a carbon source consists of rhizobiaceae bacteria production from a suspension, for sample analysis

Also Published As

Publication number Publication date
JPS6221790B2 (en) 1987-05-14

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