JPS556432A - Preparation of n-substituted phenyl glycine - Google Patents
Preparation of n-substituted phenyl glycineInfo
- Publication number
- JPS556432A JPS556432A JP7734578A JP7734578A JPS556432A JP S556432 A JPS556432 A JP S556432A JP 7734578 A JP7734578 A JP 7734578A JP 7734578 A JP7734578 A JP 7734578A JP S556432 A JPS556432 A JP S556432A
- Authority
- JP
- Japan
- Prior art keywords
- substituted phenyl
- phenyl glycine
- amines
- yields
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
Abstract
PURPOSE: To synthesize the pure N-substituted phenyl glycine through the use of safe reagents only by electrolytically reducing the specific benzylidene amines in the presence of tetraalkyl ammonium salt and carbonic acid gas with a mercury cathode.
CONSTITUTION: Benzylidene-(n)-butyl amine or other expressed by general formula R-CH=N-R' is electrolytically reduced in the electrolyte mixed with a polar nonaqueous solvent such as acetonitrile or other by using a mercury cathode in the presence of tetraalkyl ammonium salt such as tetraethyl ammonium iodide or other and carbonic acid gas. As a result, the reaction of formula I takes place and this yields the N-substituted phenyl glycine and benzyl amines being by-products. After the termination of the electrolysis, the solvent is distilled away and water is added to the residue and the benzyl amines are extracted by chloroform or other. Next, a mineral acid is added to the water layer to make its pH to 2 to 6 and this yields the N-substituted phenyl glycine as white solid.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53077345A JPS6035436B2 (en) | 1978-06-28 | 1978-06-28 | Method for producing N-substituted phenylglycine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53077345A JPS6035436B2 (en) | 1978-06-28 | 1978-06-28 | Method for producing N-substituted phenylglycine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS556432A true JPS556432A (en) | 1980-01-17 |
JPS6035436B2 JPS6035436B2 (en) | 1985-08-14 |
Family
ID=13631322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53077345A Expired JPS6035436B2 (en) | 1978-06-28 | 1978-06-28 | Method for producing N-substituted phenylglycine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6035436B2 (en) |
-
1978
- 1978-06-28 JP JP53077345A patent/JPS6035436B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6035436B2 (en) | 1985-08-14 |
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