JPS5536444A - Thiocarbostyril derivative - Google Patents

Thiocarbostyril derivative

Info

Publication number
JPS5536444A
JPS5536444A JP11044378A JP11044378A JPS5536444A JP S5536444 A JPS5536444 A JP S5536444A JP 11044378 A JP11044378 A JP 11044378A JP 11044378 A JP11044378 A JP 11044378A JP S5536444 A JPS5536444 A JP S5536444A
Authority
JP
Japan
Prior art keywords
thiocarbostyril
derivative
formula
hydroxythiocarbostyril
dihydrothiocarbostyril
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11044378A
Other languages
Japanese (ja)
Other versions
JPS6148503B2 (en
Inventor
Minoru Uchida
Takao Nishi
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP11044378A priority Critical patent/JPS5536444A/en
Publication of JPS5536444A publication Critical patent/JPS5536444A/en
Publication of JPS6148503B2 publication Critical patent/JPS6148503B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:Thiocarbostyril derivative of formula 1 (R1 is lower alkyl; R2 is cycloalkyl; the bond between the 3 and 4 positions in thiocarbostyril is double or single).
EXAMPLE: 6-[ 3-( N-Methyl-N-cyclohexylaminocarbonyl )propoxy ]-3, 4-dihydrothiocarbostyril.
USE: Antithrombosis, anti-inflammatory, antiulcerative, and antiasthmatic.
PREPARATION: A hydroxythiocarbostyril derivative of formula 2 and a haloamide of formula 3 (X is Cl, Br, I) are subjected to dehydrohalogenation reaction to give the compound of formula 1.
COPYRIGHT: (C)1980,JPO&Japio
JP11044378A 1978-09-07 1978-09-07 Thiocarbostyril derivative Granted JPS5536444A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11044378A JPS5536444A (en) 1978-09-07 1978-09-07 Thiocarbostyril derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11044378A JPS5536444A (en) 1978-09-07 1978-09-07 Thiocarbostyril derivative

Publications (2)

Publication Number Publication Date
JPS5536444A true JPS5536444A (en) 1980-03-14
JPS6148503B2 JPS6148503B2 (en) 1986-10-24

Family

ID=14535842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11044378A Granted JPS5536444A (en) 1978-09-07 1978-09-07 Thiocarbostyril derivative

Country Status (1)

Country Link
JP (1) JPS5536444A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51133277A (en) * 1975-05-15 1976-11-18 Otsuka Pharmaceut Co Ltd A process for preparing novel carbostyril derivatives
JPS51136676A (en) * 1975-05-16 1976-11-26 Otsuka Pharmaceut Co Ltd Process for preparation of carbostyril derivatives
JPS52125163A (en) * 1976-04-14 1977-10-20 Otsuka Pharmaceut Co Ltd Novel benzcyclamide derivatives
JPS5321177A (en) * 1976-08-09 1978-02-27 Otsuka Pharmaceut Co Ltd Thiocarbostyryl derivatives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51133277A (en) * 1975-05-15 1976-11-18 Otsuka Pharmaceut Co Ltd A process for preparing novel carbostyril derivatives
JPS51136676A (en) * 1975-05-16 1976-11-26 Otsuka Pharmaceut Co Ltd Process for preparation of carbostyril derivatives
JPS52125163A (en) * 1976-04-14 1977-10-20 Otsuka Pharmaceut Co Ltd Novel benzcyclamide derivatives
JPS5321177A (en) * 1976-08-09 1978-02-27 Otsuka Pharmaceut Co Ltd Thiocarbostyryl derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JPH0249768A (en) * 1988-05-02 1990-02-20 Otsuka Pharmaceut Co Ltd Carbostyril derivative

Also Published As

Publication number Publication date
JPS6148503B2 (en) 1986-10-24

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