JPS5536401A - Amino-alpha-carboline compound and mutagenic agent containing the same - Google Patents
Amino-alpha-carboline compound and mutagenic agent containing the sameInfo
- Publication number
- JPS5536401A JPS5536401A JP6877878A JP6877878A JPS5536401A JP S5536401 A JPS5536401 A JP S5536401A JP 6877878 A JP6877878 A JP 6877878A JP 6877878 A JP6877878 A JP 6877878A JP S5536401 A JPS5536401 A JP S5536401A
- Authority
- JP
- Japan
- Prior art keywords
- amino
- formula
- separated
- mutagenic agent
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
NEW MATERIAL:Amino-α-carboline compound of the formula (R=H, OH).
EXAMPLE: 2-Amino-9H-pyrido[2,3-b]indole of formula I (R=H).
USE: Mutagenic agent and plasma-conversion factor of Salmonella typhimurium TA98. The carcinogenicity of chemicals, foods, etc. can be estimated by the mutagenesis of microorganisms.
PROCESS: Soybean casein is heated to give a distilled tar, which is then dissolved with ether and acidified with HCl. This mixture is separated to an ethereal and an aqueous HCl layer under stirring. The separated aqueous HCl layer is collected and alkalized with NaOH, and ether is added. The resultant ethereal layer is separated and concentrated in vacuo to give a basic part which is extracted several times, giving a compound of the formula.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6877878A JPS5536401A (en) | 1978-06-09 | 1978-06-09 | Amino-alpha-carboline compound and mutagenic agent containing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6877878A JPS5536401A (en) | 1978-06-09 | 1978-06-09 | Amino-alpha-carboline compound and mutagenic agent containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5536401A true JPS5536401A (en) | 1980-03-14 |
| JPS5724115B2 JPS5724115B2 (en) | 1982-05-22 |
Family
ID=13383523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6877878A Granted JPS5536401A (en) | 1978-06-09 | 1978-06-09 | Amino-alpha-carboline compound and mutagenic agent containing the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5536401A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06210302A (en) * | 1992-11-24 | 1994-08-02 | Sumitomo Metal Ind Ltd | Method for rolling shape with flange |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0650916U (en) * | 1992-12-18 | 1994-07-12 | 石川島芝浦機械株式会社 | Cold wind equipment for work vehicles |
| JPH0650915U (en) * | 1992-12-18 | 1994-07-12 | 石川島芝浦機械株式会社 | Cold wind equipment for work vehicles |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1913119A1 (en) * | 1968-03-15 | 1970-08-06 | Glaxo Lab Ltd | Alpha carbolines and their method of manufacture |
-
1978
- 1978-06-09 JP JP6877878A patent/JPS5536401A/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1913119A1 (en) * | 1968-03-15 | 1970-08-06 | Glaxo Lab Ltd | Alpha carbolines and their method of manufacture |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06210302A (en) * | 1992-11-24 | 1994-08-02 | Sumitomo Metal Ind Ltd | Method for rolling shape with flange |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5724115B2 (en) | 1982-05-22 |
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