JPS5520747A - Antidepressant - Google Patents
AntidepressantInfo
- Publication number
- JPS5520747A JPS5520747A JP9428778A JP9428778A JPS5520747A JP S5520747 A JPS5520747 A JP S5520747A JP 9428778 A JP9428778 A JP 9428778A JP 9428778 A JP9428778 A JP 9428778A JP S5520747 A JPS5520747 A JP S5520747A
- Authority
- JP
- Japan
- Prior art keywords
- dops
- antidepressant
- threo
- erythro
- dihydroxyphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: An antidepressant containing 3-(3,4-dihydroxyphenyl)-serine as the effective ingredient that has different action mechanism from tricycle antidepressant.
CONSTITUTION: Said antidepressant contains 3-(3,4-dihydroxyphenyl)-serine or its salt (DOPS) as the effective ingredient. DOPS has four optical isomers of L-threo- DOPS, D-threo-DOPS, L-erythro-DOPS and D-erythro-DOPS, of which L-threo- DOPS is the most effective. DOPS inhibits the hypothermy of mouse caused by reserpine and tetrabenazine, thus showing antidepressant activity.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9428778A JPS5520747A (en) | 1978-08-01 | 1978-08-01 | Antidepressant |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9428778A JPS5520747A (en) | 1978-08-01 | 1978-08-01 | Antidepressant |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5520747A true JPS5520747A (en) | 1980-02-14 |
Family
ID=14106035
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9428778A Pending JPS5520747A (en) | 1978-08-01 | 1978-08-01 | Antidepressant |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5520747A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6067420A (en) * | 1983-09-22 | 1985-04-17 | Sumitomo Chem Co Ltd | Agent for suppressing psychokinetic excitation |
WO1999052519A3 (en) * | 1998-04-14 | 1999-12-02 | Gen Hospital Corp | Methods for treating neuropsychiatric disorders |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5049252A (en) * | 1973-08-22 | 1975-05-01 |
-
1978
- 1978-08-01 JP JP9428778A patent/JPS5520747A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5049252A (en) * | 1973-08-22 | 1975-05-01 |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6067420A (en) * | 1983-09-22 | 1985-04-17 | Sumitomo Chem Co Ltd | Agent for suppressing psychokinetic excitation |
JPH0331166B2 (en) * | 1983-09-22 | 1991-05-02 | Sumitomo Pharma | |
WO1999052519A3 (en) * | 1998-04-14 | 1999-12-02 | Gen Hospital Corp | Methods for treating neuropsychiatric disorders |
US6228875B1 (en) | 1998-04-14 | 2001-05-08 | The General Hospital Corporation | Methods for treating neuropsychiatric disorders |
US6667297B2 (en) | 1998-04-14 | 2003-12-23 | The General Hospital Corporation | Methods for treating neuropsychiatric disorders |
US6974821B2 (en) | 1998-04-14 | 2005-12-13 | The General Hospital Corporation | Methods for treating neuropsychiatric disorders |
US7704978B2 (en) | 1998-04-14 | 2010-04-27 | The General Hospital Corporation | Methods for treating neuropsychiatric disorders |
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