JPS5516142B1 - - Google Patents
Info
- Publication number
- JPS5516142B1 JPS5516142B1 JP4685472A JP4685472A JPS5516142B1 JP S5516142 B1 JPS5516142 B1 JP S5516142B1 JP 4685472 A JP4685472 A JP 4685472A JP 4685472 A JP4685472 A JP 4685472A JP S5516142 B1 JPS5516142 B1 JP S5516142B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH696971A CH549339A (de) | 1971-05-12 | 1971-05-12 | Herbizides mittel. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5516142B1 true JPS5516142B1 (enExample) | 1980-04-30 |
Family
ID=4317885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4685472A Pending JPS5516142B1 (enExample) | 1971-05-12 | 1972-05-11 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3845055A (enExample) |
| JP (1) | JPS5516142B1 (enExample) |
| CH (1) | CH549339A (enExample) |
| DE (1) | DE2222729A1 (enExample) |
| FR (1) | FR2139411A5 (enExample) |
| IL (1) | IL39346A (enExample) |
| IT (1) | IT955414B (enExample) |
| NL (1) | NL7206347A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015517574A (ja) * | 2012-05-22 | 2015-06-22 | ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | がん治療のためのピリミジン化合物 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1523274A (en) * | 1974-08-05 | 1978-08-31 | Ici Ltd | Herbicidal compositions containing substituted pyrimidine |
| CH617833A5 (enExample) * | 1975-07-07 | 1980-06-30 | Ciba Geigy Ag | |
| USRE31136E (en) * | 1976-08-27 | 1983-02-01 | Fmc Corporation | Herbicidal 5-pyrimidinecarbonitriles |
| US4092150A (en) * | 1976-08-27 | 1978-05-30 | Fmc Corporation | Herbicidal 5-pyrimidinecarbonitriles |
| US4118217A (en) * | 1977-01-06 | 1978-10-03 | Farmland Industries, Incorporated | Herbicidally active substituted pyrimidine compounds and method of using same |
| JPH0720943B2 (ja) * | 1988-08-19 | 1995-03-08 | 宇部興産株式会社 | アミノピリミジン誘導体、その製法及び殺虫・殺菌剤 |
| EP0850228A1 (en) * | 1995-09-01 | 1998-07-01 | Signal Pharmaceuticals, Inc. | Pyrimidine carboxamides and related compounds and methods for treating inflammatory conditions |
| US5811428A (en) * | 1995-12-18 | 1998-09-22 | Signal Pharmaceuticals, Inc. | Pyrimidine carboxamides and related compounds and methods for treating inflammatory conditions |
| US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
| US7504396B2 (en) * | 2003-06-24 | 2009-03-17 | Amgen Inc. | Substituted heterocyclic compounds and methods of use |
| DK2699553T3 (da) | 2011-04-22 | 2024-01-29 | Signal Pharm Llc | Substituerede diaminocarboxamid- og diaminocarbonitrilpyrimidiner, sammensætninger deraf og fremgangsmåder til behandling dermed |
| NZ715903A (en) | 2014-01-30 | 2017-06-30 | Signal Pharm Llc | Solid forms of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide, compositions thereof and methods of their use |
| US9555030B2 (en) * | 2014-04-11 | 2017-01-31 | The University Of North Carolina At Chapel Hill | Therapeutic uses of selected pyrazolopyrimidine compounds with anti-Mer tyrosine kinase activity |
| NZ732793A (en) | 2014-12-16 | 2023-07-28 | Signal Pharm Llc | Formulations of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methycyclohexylamino)-pyrimidine-5-carboxamide |
| JP6903577B2 (ja) | 2014-12-16 | 2021-07-14 | シグナル ファーマシューティカルズ，エルエルシー | 皮膚におけるｃ−Ｊｕｎ Ｎ末端キナーゼの阻害の測定方法 |
| EP3250557B1 (en) | 2015-01-29 | 2024-11-20 | Signal Pharmaceuticals, LLC | Isotopologues of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide |
| CN107922287B (zh) | 2015-07-24 | 2021-04-09 | 细胞基因公司 | 合成(1r,2r,5r)-5-氨基-2-甲基环己醇盐酸盐的方法和其中可用的中间体 |
-
1971
- 1971-05-12 CH CH696971A patent/CH549339A/xx not_active IP Right Cessation
-
1972
- 1972-05-03 IL IL39346A patent/IL39346A/xx unknown
- 1972-05-08 US US00251411A patent/US3845055A/en not_active Expired - Lifetime
- 1972-05-09 DE DE19722222729 patent/DE2222729A1/de not_active Ceased
- 1972-05-10 FR FR7216725A patent/FR2139411A5/fr not_active Expired
- 1972-05-10 IT IT24199/72A patent/IT955414B/it active
- 1972-05-10 NL NL7206347A patent/NL7206347A/xx not_active Application Discontinuation
- 1972-05-11 JP JP4685472A patent/JPS5516142B1/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015517574A (ja) * | 2012-05-22 | 2015-06-22 | ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | がん治療のためのピリミジン化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL39346A0 (en) | 1972-08-30 |
| DE2222729A1 (de) | 1972-11-16 |
| CH549339A (de) | 1974-05-31 |
| FR2139411A5 (enExample) | 1973-01-05 |
| NL7206347A (enExample) | 1972-11-14 |
| IL39346A (en) | 1975-04-25 |
| US3845055A (en) | 1974-10-29 |
| IT955414B (it) | 1973-09-29 |