JPS55151590A - Hexahydronaphtho(2',1':4,5)imidazo(2,1-b)thiazole and its preparation - Google Patents

Hexahydronaphtho(2',1':4,5)imidazo(2,1-b)thiazole and its preparation

Info

Publication number
JPS55151590A
JPS55151590A JP5798679A JP5798679A JPS55151590A JP S55151590 A JPS55151590 A JP S55151590A JP 5798679 A JP5798679 A JP 5798679A JP 5798679 A JP5798679 A JP 5798679A JP S55151590 A JPS55151590 A JP S55151590A
Authority
JP
Japan
Prior art keywords
formula
compound shown
hexahydronaphtho
imidazo
thiazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5798679A
Other languages
Japanese (ja)
Inventor
Yasukata Shikayama
Takeshi Hara
Masahiko Saito
Yoji Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP5798679A priority Critical patent/JPS55151590A/en
Publication of JPS55151590A publication Critical patent/JPS55151590A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:The title compound shown by the formula I (R is lower alkyl, lower alkoxy, or halogen; n is 0 or 1W4; B and C rings are cis or trans form).
EXAMPLE: Trans-5,6,6a,9,10,11a-hexahydronaphtho[ 2',1':4,5 ]imidazo[ 2,1-b ] thiazole.
USE: A drug useful for treatment of cancer and autoimmune disease, e.g., rheumatoid arthritis having immuization or immunosuppression.
PROCESS: A tetrahydronaphtho[1,2-d]imidazoline-2-thione is reacted with a compound shown by the formula [Y or Z is halogen, arylsulfonyloxy or alkanesulfonyloxy) to give a compound shown by the formula I. The compound shown by the formula II is also novel one.
COPYRIGHT: (C)1980,JPO&Japio
JP5798679A 1979-05-14 1979-05-14 Hexahydronaphtho(2',1':4,5)imidazo(2,1-b)thiazole and its preparation Pending JPS55151590A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5798679A JPS55151590A (en) 1979-05-14 1979-05-14 Hexahydronaphtho(2',1':4,5)imidazo(2,1-b)thiazole and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5798679A JPS55151590A (en) 1979-05-14 1979-05-14 Hexahydronaphtho(2',1':4,5)imidazo(2,1-b)thiazole and its preparation

Publications (1)

Publication Number Publication Date
JPS55151590A true JPS55151590A (en) 1980-11-26

Family

ID=13071323

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5798679A Pending JPS55151590A (en) 1979-05-14 1979-05-14 Hexahydronaphtho(2',1':4,5)imidazo(2,1-b)thiazole and its preparation

Country Status (1)

Country Link
JP (1) JPS55151590A (en)

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