JPS5488254A - Production of 17-hydroxypregn-5-ene-20-ine-3-one - Google Patents
Production of 17-hydroxypregn-5-ene-20-ine-3-oneInfo
- Publication number
- JPS5488254A JPS5488254A JP15419677A JP15419677A JPS5488254A JP S5488254 A JPS5488254 A JP S5488254A JP 15419677 A JP15419677 A JP 15419677A JP 15419677 A JP15419677 A JP 15419677A JP S5488254 A JPS5488254 A JP S5488254A
- Authority
- JP
- Japan
- Prior art keywords
- ene
- ethynylation
- reaction
- androst
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BTTWKVFKBPAFDK-UHFFFAOYSA-N (9beta,10alpha)-Androst-4-ene-3,17-dione Natural products OC1CCC2(C)C3CCC(C)(C(CC4)O)C4C3CCC2=C1 BTTWKVFKBPAFDK-UHFFFAOYSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- AEMFNILZOJDQLW-QAGGRKNESA-N androst-4-ene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 AEMFNILZOJDQLW-QAGGRKNESA-N 0.000 abstract 2
- AEMFNILZOJDQLW-UHFFFAOYSA-N androstenedione Natural products O=C1CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 AEMFNILZOJDQLW-UHFFFAOYSA-N 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000001247 metal acetylides Chemical class 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000008043 acidic salts Chemical class 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 abstract 1
- 229960002256 spironolactone Drugs 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15419677A JPS5488254A (en) | 1977-12-21 | 1977-12-21 | Production of 17-hydroxypregn-5-ene-20-ine-3-one |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15419677A JPS5488254A (en) | 1977-12-21 | 1977-12-21 | Production of 17-hydroxypregn-5-ene-20-ine-3-one |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5488254A true JPS5488254A (en) | 1979-07-13 |
| JPS6115878B2 JPS6115878B2 (enrdf_load_stackoverflow) | 1986-04-26 |
Family
ID=15578927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15419677A Granted JPS5488254A (en) | 1977-12-21 | 1977-12-21 | Production of 17-hydroxypregn-5-ene-20-ine-3-one |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5488254A (enrdf_load_stackoverflow) |
-
1977
- 1977-12-21 JP JP15419677A patent/JPS5488254A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6115878B2 (enrdf_load_stackoverflow) | 1986-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FPAY | Renewal fee payment (prs date is renewal date of database) |
Year of fee payment: 6 Free format text: PAYMENT UNTIL: 20070907 |
|
| FPAY | Renewal fee payment (prs date is renewal date of database) |
Year of fee payment: 7 Free format text: PAYMENT UNTIL: 20080907 |
|
| LAPS | Cancellation because of no payment of annual fees |