JPS5476598A - Production of riboflavin-5'-monophosphate - Google Patents

Production of riboflavin-5'-monophosphate

Info

Publication number
JPS5476598A
JPS5476598A JP14089777A JP14089777A JPS5476598A JP S5476598 A JPS5476598 A JP S5476598A JP 14089777 A JP14089777 A JP 14089777A JP 14089777 A JP14089777 A JP 14089777A JP S5476598 A JPS5476598 A JP S5476598A
Authority
JP
Japan
Prior art keywords
riboflavin
phosphates
reaction
solvent
monophosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14089777A
Other languages
Japanese (ja)
Other versions
JPS614398B2 (en
Inventor
Kosuke Yamauchi
Yutaka Haneda
Yoshiyuki Yamada
Kyoichi Fujii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP14089777A priority Critical patent/JPS5476598A/en
Publication of JPS5476598A publication Critical patent/JPS5476598A/en
Publication of JPS614398B2 publication Critical patent/JPS614398B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: The reaction of riboflavin with phosphorus oxyhalide or its hydrate is conducted in a specific solvent such as trialkoxyalkyl phosphate to produce title compound having vitamin B2 activity in high yield and selectivity.
CONSTITUTION: Riboflavin-5'-monophosphate is prepared by the reaction of riboflavin with phosphorus oxyhalide or its hydrate wherein as a solvent is employed at least one selected from the group consisting of trialkoxyalkyl phosphates, monoalkyldialkoxyalkyl phosphates, monoalkoxyalkyldialkyl phosphates and the amount of the solvent is 5W30 times the weight of riboflavin and the phosphorylation agent is 2.0W20 times the molar quantity of riboflavin.
EFFECT: The solvents employed in the reaction and extraction processes can be recovered in high rate, thus the method is practically advantageous.
COPYRIGHT: (C)1979,JPO&Japio
JP14089777A 1977-11-24 1977-11-24 Production of riboflavin-5'-monophosphate Granted JPS5476598A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14089777A JPS5476598A (en) 1977-11-24 1977-11-24 Production of riboflavin-5'-monophosphate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14089777A JPS5476598A (en) 1977-11-24 1977-11-24 Production of riboflavin-5'-monophosphate

Publications (2)

Publication Number Publication Date
JPS5476598A true JPS5476598A (en) 1979-06-19
JPS614398B2 JPS614398B2 (en) 1986-02-08

Family

ID=15279326

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14089777A Granted JPS5476598A (en) 1977-11-24 1977-11-24 Production of riboflavin-5'-monophosphate

Country Status (1)

Country Link
JP (1) JPS5476598A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110293759A1 (en) * 2010-06-01 2011-12-01 Calitoga Llc Nutritional supplement for recovery, repair, and maintenance

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110293759A1 (en) * 2010-06-01 2011-12-01 Calitoga Llc Nutritional supplement for recovery, repair, and maintenance
US9333228B2 (en) * 2010-06-01 2016-05-10 Top Doctors Labs, Llc Nutritional supplement for recovery, repair, and maintenance

Also Published As

Publication number Publication date
JPS614398B2 (en) 1986-02-08

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