JPS5463067A - Oncostatic drugs and their preparation - Google Patents

Oncostatic drugs and their preparation

Info

Publication number
JPS5463067A
JPS5463067A JP6090877A JP6090877A JPS5463067A JP S5463067 A JPS5463067 A JP S5463067A JP 6090877 A JP6090877 A JP 6090877A JP 6090877 A JP6090877 A JP 6090877A JP S5463067 A JPS5463067 A JP S5463067A
Authority
JP
Japan
Prior art keywords
oncostatic
drugs
aclacinomycin
atcc
streptomyces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6090877A
Other languages
Japanese (ja)
Other versions
JPS5625239B2 (en
Inventor
Hamao Umezawa
Tomio Takeuchi
Shunichi Oki
Taiji Inui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP6090877A priority Critical patent/JPS5463067A/en
Priority to CH1159577A priority patent/CH637160A5/en
Priority to NLAANVRAGE7710380,A priority patent/NL176004C/en
Priority to DE2743654A priority patent/DE2743654B2/en
Priority to DK435577A priority patent/DK145200C/en
Priority to IE2007/77A priority patent/IE46236B1/en
Priority to HU77ZA402A priority patent/HU181999B/en
Priority to FR7729595A priority patent/FR2403350A1/en
Priority to NO773353A priority patent/NO148959C/en
Priority to CA287,886A priority patent/CA1100895A/en
Priority to SE7710972A priority patent/SE425798B/en
Priority to US05/838,617 priority patent/US4207313A/en
Priority to YU2352/77A priority patent/YU40483B/en
Priority to GR54487A priority patent/GR63996B/en
Priority to FI772915A priority patent/FI57444C/en
Priority to GB41047/77A priority patent/GB1589536A/en
Priority to AU29337/77A priority patent/AU505971B2/en
Priority to LU78242A priority patent/LU78242A1/xx
Priority to NO78781949A priority patent/NO147953C/en
Priority to ES471823A priority patent/ES471823A1/en
Priority to US05/928,637 priority patent/US4209588A/en
Priority to US06/037,804 priority patent/US4245045A/en
Publication of JPS5463067A publication Critical patent/JPS5463067A/en
Priority to FI800169A priority patent/FI63945C/en
Publication of JPS5625239B2 publication Critical patent/JPS5625239B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Aclacinomycin Y (named by the inventors) of formula I, its acid salt, and nucleic acid complex. USE:Oncostatic drugs, particularly remedies for infectious diseases of Gram-positive bacteria and anti malignant oncostatic drugs. PROCESS:Aclacinomycin Y-producing bacteria, preferably one type selected from Streptomyces galilaeus MA 144-M1 FEMP No.2455 (ATCC 31133) and Streptomyces galilaeus ATCC 14969 which belong to the genus Streptomyces are acrobically cultured according to the conventional method in a medium containing the well- known nutrients which can be utilized by ordinary microorganisms. The objective commpound is separated from the liquid medium thus obtained and purified as a simple component. Alternatively, Aclacinomycin A or/and MA114-NI is converted to the objective compound by enzymic reaction, and the reaction mixture is treated in the same way as described above.
JP6090877A 1976-10-05 1977-05-24 Oncostatic drugs and their preparation Granted JPS5463067A (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
JP6090877A JPS5463067A (en) 1977-05-24 1977-05-24 Oncostatic drugs and their preparation
CH1159577A CH637160A5 (en) 1976-10-05 1977-09-22 PROCESS FOR THE MANUFACTURE OF ANTHRACYCLINE GLUCOSIDES.
NLAANVRAGE7710380,A NL176004C (en) 1976-10-05 1977-09-22 PROCESS FOR PREPARING MEDICINES WITH ANTITUMOR ACTION BASED ON ANTHRACYCLINE GLYCOSIDES AND PROCESS FOR PREPARING ANTHRACYCLINE GLYCOSIDES.
DE2743654A DE2743654B2 (en) 1976-10-05 1977-09-28 Anthracycline glycosides of group MA 144-, processes for their production and pharmaceutical preparations containing these glycosides
DK435577A DK145200C (en) 1976-10-05 1977-09-30 METHOD OF PREPARING ANTHRACYCLING LYCOSIDE ANTIBIOTICS
IE2007/77A IE46236B1 (en) 1976-10-05 1977-09-30 Antitumor anthracycline antibiotics
HU77ZA402A HU181999B (en) 1976-10-05 1977-09-30 Process for producing new citostatic antracycline antibiotics
FR7729595A FR2403350A1 (en) 1976-10-05 1977-09-30 NEW ANTIBIOTIC ANTHRACYCLINE AGAINST TUMORS
NO773353A NO148959C (en) 1976-10-05 1977-09-30 PROCEDURE FOR THE PREPARATION OF TUMOR-EFFECTIVE ANTACYCYLICOSIDE ANTIBIOTICS, MA MA 144
CA287,886A CA1100895A (en) 1976-10-05 1977-09-30 Antitumor anthracylcine antibiotics
SE7710972A SE425798B (en) 1976-10-05 1977-09-30 PROCEDURE FOR THE PREPARATION OF NEW ANTITUMOR ANTRA-CYCLINE ANTIBIOTICS NAMED MA 144 WITH ITS ISSUED FORM BY CULTIVATION OF AND FOR BEING KNOWN STREPTOMYCESS STEMS AND EXPLOITATION OF THE STATED SUBSTANCES
US05/838,617 US4207313A (en) 1976-10-05 1977-10-03 Anthracycline antibiotics
YU2352/77A YU40483B (en) 1976-10-05 1977-10-03 Process for preparing anthracycline antibiotetics
GR54487A GR63996B (en) 1976-10-05 1977-10-03 Method for the preparation of new antibiotics of carboncycline against tumours
FI772915A FI57444C (en) 1976-10-05 1977-10-03 FOERFARANDE FOER FRAMSTAELLNING AV NYA TUMOERER MOTVERKANDE ANTRACYKLIN-GLYKOSID ANTIBIOTIKA MA 144
GB41047/77A GB1589536A (en) 1976-10-05 1977-10-03 Antitumor anthracycline antibiotics
AU29337/77A AU505971B2 (en) 1976-10-05 1977-10-04 Antitumour anthracycling antibiotics
LU78242A LU78242A1 (en) 1976-10-05 1977-10-04
NO78781949A NO147953C (en) 1976-10-05 1978-06-05 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE ANTHRACYCLING GLOSOSIDES
ES471823A ES471823A1 (en) 1976-10-05 1978-07-17 Anthracycline antibiotics
US05/928,637 US4209588A (en) 1976-10-05 1978-07-27 Process for producing new antitumor anthracycline antibiotics
US06/037,804 US4245045A (en) 1976-10-05 1979-05-10 Method of producing anthracycline antibiotics
FI800169A FI63945C (en) 1976-10-05 1980-01-21 FOERFARANDE FOER FRAMSTAELLNING AV NYA TUMOERER MOTVERKANDE ANRACYKLINGLYKOSIDANTIBIOTIKA

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6090877A JPS5463067A (en) 1977-05-24 1977-05-24 Oncostatic drugs and their preparation

Publications (2)

Publication Number Publication Date
JPS5463067A true JPS5463067A (en) 1979-05-21
JPS5625239B2 JPS5625239B2 (en) 1981-06-11

Family

ID=13155925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6090877A Granted JPS5463067A (en) 1976-10-05 1977-05-24 Oncostatic drugs and their preparation

Country Status (1)

Country Link
JP (1) JPS5463067A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0463929U (en) * 1990-10-08 1992-06-01

Also Published As

Publication number Publication date
JPS5625239B2 (en) 1981-06-11

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