JPS5463067A - Oncostatic drugs and their preparation - Google Patents
Oncostatic drugs and their preparationInfo
- Publication number
- JPS5463067A JPS5463067A JP6090877A JP6090877A JPS5463067A JP S5463067 A JPS5463067 A JP S5463067A JP 6090877 A JP6090877 A JP 6090877A JP 6090877 A JP6090877 A JP 6090877A JP S5463067 A JPS5463067 A JP S5463067A
- Authority
- JP
- Japan
- Prior art keywords
- oncostatic
- drugs
- aclacinomycin
- atcc
- streptomyces
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Aclacinomycin Y (named by the inventors) of formula I, its acid salt, and nucleic acid complex. USE:Oncostatic drugs, particularly remedies for infectious diseases of Gram-positive bacteria and anti malignant oncostatic drugs. PROCESS:Aclacinomycin Y-producing bacteria, preferably one type selected from Streptomyces galilaeus MA 144-M1 FEMP No.2455 (ATCC 31133) and Streptomyces galilaeus ATCC 14969 which belong to the genus Streptomyces are acrobically cultured according to the conventional method in a medium containing the well- known nutrients which can be utilized by ordinary microorganisms. The objective commpound is separated from the liquid medium thus obtained and purified as a simple component. Alternatively, Aclacinomycin A or/and MA114-NI is converted to the objective compound by enzymic reaction, and the reaction mixture is treated in the same way as described above.
Priority Applications (23)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6090877A JPS5463067A (en) | 1977-05-24 | 1977-05-24 | Oncostatic drugs and their preparation |
CH1159577A CH637160A5 (en) | 1976-10-05 | 1977-09-22 | PROCESS FOR THE MANUFACTURE OF ANTHRACYCLINE GLUCOSIDES. |
NLAANVRAGE7710380,A NL176004C (en) | 1976-10-05 | 1977-09-22 | PROCESS FOR PREPARING MEDICINES WITH ANTITUMOR ACTION BASED ON ANTHRACYCLINE GLYCOSIDES AND PROCESS FOR PREPARING ANTHRACYCLINE GLYCOSIDES. |
DE2743654A DE2743654B2 (en) | 1976-10-05 | 1977-09-28 | Anthracycline glycosides of group MA 144-, processes for their production and pharmaceutical preparations containing these glycosides |
DK435577A DK145200C (en) | 1976-10-05 | 1977-09-30 | METHOD OF PREPARING ANTHRACYCLING LYCOSIDE ANTIBIOTICS |
IE2007/77A IE46236B1 (en) | 1976-10-05 | 1977-09-30 | Antitumor anthracycline antibiotics |
HU77ZA402A HU181999B (en) | 1976-10-05 | 1977-09-30 | Process for producing new citostatic antracycline antibiotics |
FR7729595A FR2403350A1 (en) | 1976-10-05 | 1977-09-30 | NEW ANTIBIOTIC ANTHRACYCLINE AGAINST TUMORS |
NO773353A NO148959C (en) | 1976-10-05 | 1977-09-30 | PROCEDURE FOR THE PREPARATION OF TUMOR-EFFECTIVE ANTACYCYLICOSIDE ANTIBIOTICS, MA MA 144 |
CA287,886A CA1100895A (en) | 1976-10-05 | 1977-09-30 | Antitumor anthracylcine antibiotics |
SE7710972A SE425798B (en) | 1976-10-05 | 1977-09-30 | PROCEDURE FOR THE PREPARATION OF NEW ANTITUMOR ANTRA-CYCLINE ANTIBIOTICS NAMED MA 144 WITH ITS ISSUED FORM BY CULTIVATION OF AND FOR BEING KNOWN STREPTOMYCESS STEMS AND EXPLOITATION OF THE STATED SUBSTANCES |
US05/838,617 US4207313A (en) | 1976-10-05 | 1977-10-03 | Anthracycline antibiotics |
YU2352/77A YU40483B (en) | 1976-10-05 | 1977-10-03 | Process for preparing anthracycline antibiotetics |
GR54487A GR63996B (en) | 1976-10-05 | 1977-10-03 | Method for the preparation of new antibiotics of carboncycline against tumours |
FI772915A FI57444C (en) | 1976-10-05 | 1977-10-03 | FOERFARANDE FOER FRAMSTAELLNING AV NYA TUMOERER MOTVERKANDE ANTRACYKLIN-GLYKOSID ANTIBIOTIKA MA 144 |
GB41047/77A GB1589536A (en) | 1976-10-05 | 1977-10-03 | Antitumor anthracycline antibiotics |
AU29337/77A AU505971B2 (en) | 1976-10-05 | 1977-10-04 | Antitumour anthracycling antibiotics |
LU78242A LU78242A1 (en) | 1976-10-05 | 1977-10-04 | |
NO78781949A NO147953C (en) | 1976-10-05 | 1978-06-05 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE ANTHRACYCLING GLOSOSIDES |
ES471823A ES471823A1 (en) | 1976-10-05 | 1978-07-17 | Anthracycline antibiotics |
US05/928,637 US4209588A (en) | 1976-10-05 | 1978-07-27 | Process for producing new antitumor anthracycline antibiotics |
US06/037,804 US4245045A (en) | 1976-10-05 | 1979-05-10 | Method of producing anthracycline antibiotics |
FI800169A FI63945C (en) | 1976-10-05 | 1980-01-21 | FOERFARANDE FOER FRAMSTAELLNING AV NYA TUMOERER MOTVERKANDE ANRACYKLINGLYKOSIDANTIBIOTIKA |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6090877A JPS5463067A (en) | 1977-05-24 | 1977-05-24 | Oncostatic drugs and their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5463067A true JPS5463067A (en) | 1979-05-21 |
JPS5625239B2 JPS5625239B2 (en) | 1981-06-11 |
Family
ID=13155925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6090877A Granted JPS5463067A (en) | 1976-10-05 | 1977-05-24 | Oncostatic drugs and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5463067A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0463929U (en) * | 1990-10-08 | 1992-06-01 |
-
1977
- 1977-05-24 JP JP6090877A patent/JPS5463067A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5625239B2 (en) | 1981-06-11 |
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