JPS5461139A - Novel phenylethanolamine derivative and its preparation - Google Patents
Novel phenylethanolamine derivative and its preparationInfo
- Publication number
- JPS5461139A JPS5461139A JP12786777A JP12786777A JPS5461139A JP S5461139 A JPS5461139 A JP S5461139A JP 12786777 A JP12786777 A JP 12786777A JP 12786777 A JP12786777 A JP 12786777A JP S5461139 A JPS5461139 A JP S5461139A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- remedy
- alkyl
- blocking effect
- phenylethanolamine derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Phenylethanolamine derivative I (X is alkyl, H, halogen, alkylthio; R1 is H, alkyl; n is O, 1-3; R2 is aryl, benzoxane, aryloxy, arylthio).
EXAMPLE: 2-Chloro-5-[1-hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl]benzamide.
USE: Hypotensive agent having low side effects; remedy for peripheral inadequacy; remedy for stenocardia (having both β-adrenaline blocking effect and α- adrenaline blocking effect).
PROCESS: The title compound can be prepared, e.g. by reacting an epoxide II with an amine III, and when Y is a group which can be converted to carbamoyl group, converting to carbamoyl group.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12786777A JPS5461139A (en) | 1977-10-25 | 1977-10-25 | Novel phenylethanolamine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12786777A JPS5461139A (en) | 1977-10-25 | 1977-10-25 | Novel phenylethanolamine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5461139A true JPS5461139A (en) | 1979-05-17 |
Family
ID=14970605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12786777A Pending JPS5461139A (en) | 1977-10-25 | 1977-10-25 | Novel phenylethanolamine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5461139A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7829545B2 (en) | 1998-05-06 | 2010-11-09 | Duke University | Method of treating bladder and lower urinary tract syndromes |
-
1977
- 1977-10-25 JP JP12786777A patent/JPS5461139A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7829545B2 (en) | 1998-05-06 | 2010-11-09 | Duke University | Method of treating bladder and lower urinary tract syndromes |
US7858312B2 (en) | 1998-05-06 | 2010-12-28 | Duke University | Method of treating bladder and lower urinary tract syndromes |
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