JPS5441888A - Preparation of 7-methoxycephalosporin derivative - Google Patents

Preparation of 7-methoxycephalosporin derivative

Info

Publication number
JPS5441888A
JPS5441888A JP10693277A JP10693277A JPS5441888A JP S5441888 A JPS5441888 A JP S5441888A JP 10693277 A JP10693277 A JP 10693277A JP 10693277 A JP10693277 A JP 10693277A JP S5441888 A JPS5441888 A JP S5441888A
Authority
JP
Japan
Prior art keywords
compound
derivative
aminoadipoyl
formulai
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10693277A
Other languages
Japanese (ja)
Other versions
JPS5948834B2 (en
Inventor
Tetsuo Hiraoka
Junichi Nakazawa
Tokio Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP52106932A priority Critical patent/JPS5948834B2/en
Publication of JPS5441888A publication Critical patent/JPS5441888A/en
Publication of JPS5948834B2 publication Critical patent/JPS5948834B2/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE: The transacylation on 7-position is conducted by using 7-aminoadipoyl derivative without use of acid chloride to produce antibiotics or their intermediates.
CONSTITUTION: A compound of formulaI(R1 is protecting group; R2 is protecting group; R3 is H, acyloxy, heterocycle-thio) is reacted with a halogenating agent to form a compound of formula II (X is halogen), which is made to act on R4- COOM (R4 is residue of carboxylic acid; M is alkali metal) to give a compound of formula III. Then the aminoadipoyl residue is eliminated therefrom the afford 7-methoxycephaloaporin derivative of formulaI.
COPYRIGHT: (C)1979,JPO&Japio
JP52106932A 1977-09-06 1977-09-06 Method for producing 7-methoxycephalosporin derivatives Expired JPS5948834B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP52106932A JPS5948834B2 (en) 1977-09-06 1977-09-06 Method for producing 7-methoxycephalosporin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52106932A JPS5948834B2 (en) 1977-09-06 1977-09-06 Method for producing 7-methoxycephalosporin derivatives

Publications (2)

Publication Number Publication Date
JPS5441888A true JPS5441888A (en) 1979-04-03
JPS5948834B2 JPS5948834B2 (en) 1984-11-29

Family

ID=14446165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52106932A Expired JPS5948834B2 (en) 1977-09-06 1977-09-06 Method for producing 7-methoxycephalosporin derivatives

Country Status (1)

Country Link
JP (1) JPS5948834B2 (en)

Also Published As

Publication number Publication date
JPS5948834B2 (en) 1984-11-29

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