JPS5441881A - Aminopyridine derivatives*their manufacture and medical composition containing it - Google Patents

Aminopyridine derivatives*their manufacture and medical composition containing it

Info

Publication number
JPS5441881A
JPS5441881A JP9604778A JP9604778A JPS5441881A JP S5441881 A JPS5441881 A JP S5441881A JP 9604778 A JP9604778 A JP 9604778A JP 9604778 A JP9604778 A JP 9604778A JP S5441881 A JPS5441881 A JP S5441881A
Authority
JP
Japan
Prior art keywords
manufacture
composition containing
medical composition
aminopyridine derivatives
aminopyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9604778A
Other languages
Japanese (ja)
Inventor
Hawaado Batsugiyarii Keisu
Edowaado Soon Deibitsudo
Merii Howaito Suuzan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of JPS5441881A publication Critical patent/JPS5441881A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP9604778A 1977-08-06 1978-08-07 Aminopyridine derivatives*their manufacture and medical composition containing it Pending JPS5441881A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3305577 1977-08-06
GB1940678 1978-05-13

Publications (1)

Publication Number Publication Date
JPS5441881A true JPS5441881A (en) 1979-04-03

Family

ID=26254035

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9604778A Pending JPS5441881A (en) 1977-08-06 1978-08-07 Aminopyridine derivatives*their manufacture and medical composition containing it

Country Status (7)

Country Link
EP (1) EP0000816A1 (en)
JP (1) JPS5441881A (en)
AU (1) AU3862078A (en)
DK (1) DK346278A (en)
ES (4) ES472384A1 (en)
IL (1) IL55242A0 (en)
IT (1) IT1106623B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409712A (en) * 1980-05-30 1983-10-18 Victor Company Of Japan, Limited Method for making a stylus having a graphite electrode
US4542493A (en) * 1980-12-05 1985-09-17 Victor Company Of Japan, Limited Pickup stylus having fused diamond and ceramic bodies with conductive surfaces for capacitance disk records
WO1997000863A1 (en) * 1995-06-20 1997-01-09 Zeneca Limited Aromatic compounds and pharmaceutical compositions containing them
WO1997000864A1 (en) * 1995-06-20 1997-01-09 Zeneca Limited Aromatic compounds and pharmaceutical compositions containing them
JP2002544254A (en) * 1999-05-17 2002-12-24 ノボ ノルディスク アクティーゼルスカブ Glucagon antagonist / inverse agonist
JP2008534597A (en) * 2005-03-28 2008-08-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Pyridine derivatives useful as inhibitors of PKC-θ
US7935707B2 (en) 2007-07-02 2011-05-03 Hoffman-La Roche Inc. Imidazole derivatives

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1160229A (en) * 1979-03-13 1984-01-10 Pieter T. Haken Pyridyliminomethylbenzene derivatives
EP0018134B1 (en) * 1979-04-21 1984-03-14 Beecham Group Plc Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing them
DE3124673A1 (en) * 1981-06-24 1983-01-13 Bayer Ag, 5090 Leverkusen SUBSITUATED 2-AMINO-PYRIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE IN MEDICINAL PRODUCTS AND THE PRODUCTION THEREOF
US4552960A (en) * 1983-06-20 1985-11-12 Eli Lilly And Company Fungicidal amines
US4774251A (en) * 1984-06-18 1988-09-27 Eli Lilly And Company Method of inhibiting aromatase
US4855308A (en) * 1987-12-04 1989-08-08 Warner-Lambert Company Method of treating senile cognitive decline with N'-substituted aminopyridine adrenergic agents
US4931457B1 (en) * 1989-06-28 1993-11-16 Hoechst-Roussel Pharmaceuticals Incorporated Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders
AU630877B2 (en) * 1989-07-28 1992-11-12 Ah N. Fah Improved automatic plant watering and feeding system
FR2668770A1 (en) * 1990-11-07 1992-05-07 Nyco Sa HETEROCYCLIC AMINO ACID ESTERS AND THEIR DERIVATIVES, AND THEIR APPLICATION AS ANTI-OXIDIZING ADDITIVES FOR HIGH TEMPERATURE LUBRICATING OILS.
GB9514160D0 (en) * 1994-07-25 1995-09-13 Zeneca Ltd Aromatic compounds
GB9420557D0 (en) * 1994-10-12 1994-11-30 Zeneca Ltd Aromatic compounds
US5834468A (en) * 1995-07-07 1998-11-10 Zeneca Limited Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists
DE19845406C2 (en) * 1998-10-02 2001-10-18 Aventis Pharma Gmbh Substituted 1,3-diaryl-2-pyridin-2-yl-3- (pyridin-2-ylamino) propanol derivatives, process for their preparation, medicaments containing these compounds and their use
US6503949B1 (en) 1999-05-17 2003-01-07 Noro Nordisk A/S Glucagon antagonists/inverse agonists
CA2418912A1 (en) * 2000-08-08 2002-02-14 Ortho-Mcneil Pharmaceutical, Inc. Neuroprotective 2-pyridinamine compositions and related methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2784138A (en) * 1953-03-07 1957-03-05 Bayer Ag Fungicidal compositions of nu-arylhydroxyarylmethylamines
DE1119274B (en) * 1954-03-19 1961-12-14 Raschig Gmbh Dr F Process for the preparation of 2-amino-4-alkyl-pyridines
NL132603C (en) * 1964-08-29
DE1670522C3 (en) * 1966-05-12 1978-08-31 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt New Benzylaminopyridines
NL6707290A (en) * 1966-05-28 1967-11-29
US3450707A (en) * 1966-12-13 1969-06-17 Sterling Drug Inc Certain 2-anilino-pyridine derivatives
US3535328A (en) * 1967-09-01 1970-10-20 Exxon Research Engineering Co Certain substituted aminothioethoxy pyridines
FR2050940A5 (en) * 1969-06-30 1971-04-02 Rhone Poulenc Sa
DE2141418A1 (en) * 1970-08-18 1972-03-09 Roemmers S.A. Industrial Comercial Y Financiera, Buenos Aires Aniline derivatives of nicotinic acid and their salts
FR2155922A2 (en) * 1971-10-15 1973-05-25 Aries Robert Organophosphorus pesticides - stabilized by amino- or aminoalkyl-pyridines
DE2230392A1 (en) * 1972-06-22 1974-01-31 Cassella Farbwerke Mainkur Ag SUBSTITUTED PYRIDINE COMPOUNDS AND PROCESS FOR THEIR PRODUCTION
GB1405308A (en) * 1972-12-13 1975-09-10 Basf Ag Amino-pytidines as coupling components for azo dyes
FR2288798A1 (en) * 1974-10-24 1976-05-21 Popescu Francine Bright zinc electroplating bath - contg pyridine deriv and soluble organic polymer
DE2605467A1 (en) * 1976-02-12 1977-08-18 Basf Ag PYRIDINE COMPOUNDS

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409712A (en) * 1980-05-30 1983-10-18 Victor Company Of Japan, Limited Method for making a stylus having a graphite electrode
US4542493A (en) * 1980-12-05 1985-09-17 Victor Company Of Japan, Limited Pickup stylus having fused diamond and ceramic bodies with conductive surfaces for capacitance disk records
WO1997000863A1 (en) * 1995-06-20 1997-01-09 Zeneca Limited Aromatic compounds and pharmaceutical compositions containing them
WO1997000864A1 (en) * 1995-06-20 1997-01-09 Zeneca Limited Aromatic compounds and pharmaceutical compositions containing them
AU699691B2 (en) * 1995-06-20 1998-12-10 Astrazeneca Ab Aromatic compounds and pharmaceutical compositions containing them
CN1114598C (en) * 1995-06-20 2003-07-16 曾尼卡有限公司 Aromatic compounds and pharmaceutical compositions containing them
JP2002544254A (en) * 1999-05-17 2002-12-24 ノボ ノルディスク アクティーゼルスカブ Glucagon antagonist / inverse agonist
JP2008534597A (en) * 2005-03-28 2008-08-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Pyridine derivatives useful as inhibitors of PKC-θ
US7935707B2 (en) 2007-07-02 2011-05-03 Hoffman-La Roche Inc. Imidazole derivatives

Also Published As

Publication number Publication date
IT1106623B (en) 1985-11-11
DK346278A (en) 1979-02-07
EP0000816A1 (en) 1979-02-21
AU3862078A (en) 1980-02-07
IL55242A0 (en) 1978-09-29
ES479933A1 (en) 1979-12-01
ES472384A1 (en) 1979-10-01
ES479932A1 (en) 1979-12-01
ES479931A1 (en) 1979-12-01
IT7850601A0 (en) 1978-08-04

Similar Documents

Publication Publication Date Title
JPS5318557A (en) Novel aminoalkylfuran derivatives* their preparation and medical composition containing same
JPS5441881A (en) Aminopyridine derivatives*their manufacture and medical composition containing it
JPS53144568A (en) Novel aminoalkylthiophene derivatives* their production* medical compositions containing same and their medical uses
JPS55157564A (en) Phenylsulfonamide derivative* its manufacture and medical composition containing it
JPS5481266A (en) 11alkanoyllpyrroline derivatives*manufacture and use
JPS5441855A (en) Propenylamine*its manufacture and medical composition containing it
JPS5489031A (en) Stabilized sterilizing agent composition and production thereof
IL56017A (en) 5-cyano-prostacyclin derivatives,their manufacture and pharmaceutical compositions containing them
JPS5297921A (en) Aralkylaniline derivative* preparation thereof and medical composition containing same
DE2862107D1 (en) Glucosamine-peptide derivatives and their pharmaceutical compositions
JPS5473784A (en) Substituted quinolylguanidine derivatives and their manufacture and use
JPS542341A (en) Medical composition
JPS5466675A (en) Omegaamercaptopropionamido*its manufacture and medical composition
JPS5473765A (en) Novel 66oxidatedd3*200dioxoopregnane derivatives*their manufacture and medical composition containing said compounds
JPS5441847A (en) Pseudotrisaccharides*their manufacture and their medical use
JPS5488268A (en) Novel imidazole derivatives*their manufacture and medical composition
JPS5481284A (en) 22substituted piperazine*its manufacture and its medical composition
JPS5428829A (en) Antiithrombosis medical composition
JPS54141786A (en) Hydrogenated benzylisoquinoline derivatives* their manufacture*medical composition containing them and intermediate compounds for their manufacture
JPS52102279A (en) And its preparation and medical composition containing same
JPS52156869A (en) Production of benzomorphane derivatives and medical composition containing same
NZ187085A (en) 3-pyridazione derivatives and pharmaceutical compositions
GB2001978B (en) Pyranochromone derivatives and therapeutic compositions
JPS5470255A (en) Nnbenzylanthracycline and pharmaceutical composition
JPS5490167A (en) Novel tetracyclononane derivative*its manufacture and antivirulent medical composition containing it