JPS5421338B1 - - Google Patents
Info
- Publication number
- JPS5421338B1 JPS5421338B1 JP923471A JP923471A JPS5421338B1 JP S5421338 B1 JPS5421338 B1 JP S5421338B1 JP 923471 A JP923471 A JP 923471A JP 923471 A JP923471 A JP 923471A JP S5421338 B1 JPS5421338 B1 JP S5421338B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1376970A | 1970-02-24 | 1970-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5421338B1 true JPS5421338B1 (OSRAM) | 1979-07-30 |
Family
ID=21761656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP923471A Pending JPS5421338B1 (OSRAM) | 1970-02-24 | 1971-02-24 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3636039A (OSRAM) |
| JP (1) | JPS5421338B1 (OSRAM) |
| BE (1) | BE763298A (OSRAM) |
| BR (1) | BR7101125D0 (OSRAM) |
| CA (1) | CA967163A (OSRAM) |
| CH (2) | CH567483A5 (OSRAM) |
| DE (1) | DE2108438C2 (OSRAM) |
| DK (2) | DK134601B (OSRAM) |
| FI (1) | FI54919C (OSRAM) |
| FR (1) | FR2081537B1 (OSRAM) |
| GB (1) | GB1292768A (OSRAM) |
| IE (1) | IE35283B1 (OSRAM) |
| IL (1) | IL36237A (OSRAM) |
| NL (1) | NL171446C (OSRAM) |
| NO (1) | NO130680C (OSRAM) |
| SE (1) | SE369190B (OSRAM) |
| YU (1) | YU34407B (OSRAM) |
| ZA (1) | ZA711077B (OSRAM) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932452A (en) * | 1975-02-07 | 1976-01-13 | Morton-Norwich Products, Inc. | 1-Arylmethyl-2-imidazolidinones |
| US3966758A (en) * | 1975-06-16 | 1976-06-29 | Morton-Norwich Products, Inc. | Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones |
| US4063022A (en) * | 1976-11-22 | 1977-12-13 | Morton-Norwich Products, Inc. | Antisecretory 2-imidazolidinones |
| HU179019B (en) * | 1978-11-01 | 1982-08-28 | Gyogyszekutato Intezet | Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives |
| CA1188616A (en) * | 1981-06-11 | 1985-06-11 | Hoffmann-La Roche Limited | Pharmaceutical preparations |
| FI875724A7 (fi) * | 1986-04-29 | 1987-12-28 | Pfizer | Kalsiumista riippumaton cAMP fosfodiesteraasi-inhibiittori-masennukse nvastainen lääke. |
| US5459145A (en) * | 1988-01-19 | 1995-10-17 | Pfizer Inc. | Calcium independent camp phosphodiesterase inhibitor antidepressant |
| US5395935A (en) * | 1992-05-08 | 1995-03-07 | Pfizer Inc. | Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents |
| GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| ATE247116T1 (de) * | 1994-12-13 | 2003-08-15 | Euro Celtique Sa | Arylthioxanthine |
| JP2001523213A (ja) * | 1994-12-13 | 2001-11-20 | ユーロ−セルティーク，エス．エイ． | 三置換チオキサンチン類 |
| US6025361A (en) * | 1994-12-13 | 2000-02-15 | Euro-Celtique, S.A. | Trisubstituted thioxanthines |
| US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| US5744473A (en) * | 1996-09-16 | 1998-04-28 | Euro-Celtique, S.A. | PDE IV inhibitors: "bis-compounds" |
| EP1265861A2 (en) | 2000-03-16 | 2002-12-18 | Inflazyme Pharmaceuticals, Ltd. | Benzylated pde4 inhibitors |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN107090016A (zh) | 2011-03-01 | 2017-08-25 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| CN105764916B (zh) | 2013-06-05 | 2021-05-18 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| CN114404588A (zh) | 2013-08-09 | 2022-04-29 | 阿德利克斯公司 | 用于抑制磷酸盐转运的化合物和方法 |
| EP3972599B1 (en) | 2019-05-21 | 2025-10-22 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH518285A (de) * | 1968-05-01 | 1972-01-31 | Hoffmann La Roche | Verfahren zur Herstellung von neuen substituierten Benzylimidazolidinonen |
-
1970
- 1970-02-24 US US13769A patent/US3636039A/en not_active Expired - Lifetime
-
1971
- 1971-02-18 CH CH149474A patent/CH567483A5/xx not_active IP Right Cessation
- 1971-02-18 CH CH239371A patent/CH567482A5/xx not_active IP Right Cessation
- 1971-02-19 BR BR1125/71A patent/BR7101125D0/pt unknown
- 1971-02-19 IL IL36237A patent/IL36237A/en unknown
- 1971-02-19 ZA ZA711077A patent/ZA711077B/xx unknown
- 1971-02-22 FI FI501/71A patent/FI54919C/fi active
- 1971-02-22 DE DE2108438A patent/DE2108438C2/de not_active Expired
- 1971-02-22 NL NLAANVRAGE7102324,A patent/NL171446C/xx not_active IP Right Cessation
- 1971-02-22 IE IE213/71A patent/IE35283B1/xx unknown
- 1971-02-23 NO NO654/71A patent/NO130680C/no unknown
- 1971-02-23 BE BE763298A patent/BE763298A/xx not_active IP Right Cessation
- 1971-02-23 YU YU439/71A patent/YU34407B/xx unknown
- 1971-02-24 SE SE02361/71A patent/SE369190B/xx unknown
- 1971-02-24 FR FR7106262A patent/FR2081537B1/fr not_active Expired
- 1971-02-24 DK DK83171AA patent/DK134601B/da not_active IP Right Cessation
- 1971-02-24 JP JP923471A patent/JPS5421338B1/ja active Pending
- 1971-02-24 CA CA106,142A patent/CA967163A/en not_active Expired
- 1971-04-19 GB GB22437/71A patent/GB1292768A/en not_active Expired
-
1975
- 1975-12-15 DK DK570075A patent/DK570075A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK134601C (OSRAM) | 1977-05-16 |
| IE35283L (en) | 1971-08-24 |
| NO130680C (OSRAM) | 1975-01-22 |
| SE369190B (OSRAM) | 1974-08-12 |
| GB1292768A (en) | 1972-10-11 |
| DK134601B (da) | 1976-12-06 |
| IL36237A0 (en) | 1971-04-28 |
| YU34407B (en) | 1979-07-10 |
| FI54919B (fi) | 1978-12-29 |
| NL171446B (nl) | 1982-11-01 |
| CH567483A5 (OSRAM) | 1975-10-15 |
| NL171446C (nl) | 1983-04-05 |
| BE763298A (fr) | 1971-08-23 |
| FR2081537B1 (OSRAM) | 1974-08-23 |
| BR7101125D0 (pt) | 1973-04-26 |
| CH567482A5 (OSRAM) | 1975-10-15 |
| CA967163A (en) | 1975-05-06 |
| DE2108438C2 (de) | 1987-02-05 |
| DE2108438A1 (de) | 1971-09-09 |
| NL7102324A (OSRAM) | 1971-08-26 |
| YU43971A (en) | 1978-12-31 |
| ZA711077B (en) | 1971-10-27 |
| FI54919C (fi) | 1979-04-10 |
| FR2081537A1 (OSRAM) | 1971-12-03 |
| DK570075A (da) | 1975-12-15 |
| US3636039A (en) | 1972-01-18 |
| IE35283B1 (en) | 1976-01-07 |
| IL36237A (en) | 1974-11-29 |
| NO130680B (OSRAM) | 1974-10-14 |