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Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
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Filing date
Publication date
Application filed by Asahi Chemical Industry Co LtdfiledCriticalAsahi Chemical Industry Co Ltd
Priority to JP5386378ApriorityCriticalpatent/JPS54145656A/en
Publication of JPS54145656ApublicationCriticalpatent/JPS54145656A/en
NEW MATERIAL:A compound of formula I: (R1 is bivalent aliphatic, alicyclic, aromatic aliphatic hydrocarbon residue, etc.; R2 is aliphatic hydrocarbon group).
EXAMPLE: 1-Methoxyvinyl p-(maleimido)benzoate.
USE: Binders capable of binding sulfhydryl group-containing substances to amino group-containing substances efficiently, e.g. in preparing active substances by binding a physiologically active substance, such as a protein, to other proteins or non- protein substances.
PROCESS: A compound of formula II is reacted with an alkoxyacetylene in a solvent, e.g. an ether or ketone, at - 10 to 80°C, preferably in the presence of a mercuric salt, e.g. mercuric acetate, to give the objective compound of formula I.
Substituted pyridylsulfinylbenzimidazoles having gastric acid secretion properties,pharmaceutical preparations containing same,and intermediates for their preparation
METHOD OF ANALOGUE FOR THE PREPARATION OF PEPTIDS CONTAINING 2-7 AMINO ACID RESIDUES, DESAMINODIPEPTIDES OR AMIDES THEREOF WITH UBIQUITIN SIMILAR ACTIVITY OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS
Process for the resolution of d, 12-(6-methoxy-2-napathyl) propionic acid. a mixture of the salts of these d and i acids;a pharmaceutical composition containing a salt of the d acid; a salt of the d acid