JPS54141763A - O-(maleimidoacyl)hydroxamic acid derivative - Google Patents
O-(maleimidoacyl)hydroxamic acid derivativeInfo
- Publication number
- JPS54141763A JPS54141763A JP4805178A JP4805178A JPS54141763A JP S54141763 A JPS54141763 A JP S54141763A JP 4805178 A JP4805178 A JP 4805178A JP 4805178 A JP4805178 A JP 4805178A JP S54141763 A JPS54141763 A JP S54141763A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- aliphatic
- maleimidoacyl
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pyrrole Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
NEW MATERIAL:An o-(maleimidoacyl) hydroxamic acid derivative of formula I: (R1 is bivalent aliphatic, alicyclic, aromatic aliphatic hydrocarbon residue, or bivalent aromatic ring-containing residue; R2 and R3 are aliphatic or aromatic hydrocarbon residues, R3 is H).
EXAMPLE: o-(p-Maleimidobenzoyl)p-chlorobenzhydroxamic acid.
USE: Binders useful in the field of biochemistry of medicine, e.g. a binder of enzymes and carrier substances in enzyme immobilization, for binding sulfhydryl group- containing substances to amino group-containing substances without degrading the characteristics of substrates, e.g. protein or a physiologically active substance, efficiently. Intermediates for bactericidal pesticides.
PROCESS: A compound of formula II is reacted with a compound of formula III in the presence of a dehydrating and condensing agent, e.g. carbodiimide, to give the objective compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4805178A JPS54141763A (en) | 1978-04-22 | 1978-04-22 | O-(maleimidoacyl)hydroxamic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4805178A JPS54141763A (en) | 1978-04-22 | 1978-04-22 | O-(maleimidoacyl)hydroxamic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54141763A true JPS54141763A (en) | 1979-11-05 |
Family
ID=12792529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4805178A Pending JPS54141763A (en) | 1978-04-22 | 1978-04-22 | O-(maleimidoacyl)hydroxamic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54141763A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4971598A (en) * | 1988-08-30 | 1990-11-20 | Mobil Oil Corporation | Reaction products of alkenyl succinimides with ethylenediamine carboxy acids as fuel detergents |
US5252457A (en) * | 1991-10-08 | 1993-10-12 | Eastman Kodak Company | Wash composition containing signal stop reagent, test kit and method of use with peroxidase-labeled specific binding ligand |
US5460946A (en) * | 1991-10-08 | 1995-10-24 | Eastman Kodak Company | Diagnostic test kit and specific binding assay using modulator of signal resulting from peroxidase label |
US20120027680A1 (en) * | 2002-07-19 | 2012-02-02 | The General Hospital Corporation | Oxime conjugates and methods for their formation and use |
-
1978
- 1978-04-22 JP JP4805178A patent/JPS54141763A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4971598A (en) * | 1988-08-30 | 1990-11-20 | Mobil Oil Corporation | Reaction products of alkenyl succinimides with ethylenediamine carboxy acids as fuel detergents |
US5252457A (en) * | 1991-10-08 | 1993-10-12 | Eastman Kodak Company | Wash composition containing signal stop reagent, test kit and method of use with peroxidase-labeled specific binding ligand |
US5460946A (en) * | 1991-10-08 | 1995-10-24 | Eastman Kodak Company | Diagnostic test kit and specific binding assay using modulator of signal resulting from peroxidase label |
US5482831A (en) * | 1991-10-08 | 1996-01-09 | Johnson & Johnson Clinical Diagnostics, Inc. | Wash composition containing signal stop reagent, test kit and method of use with peroxidase-labeled specific binding ligand |
US20120027680A1 (en) * | 2002-07-19 | 2012-02-02 | The General Hospital Corporation | Oxime conjugates and methods for their formation and use |
US8361442B2 (en) * | 2002-07-19 | 2013-01-29 | The General Hospital Corporation | Oxime conjugates and methods for their formation and use |
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