JPS54133193A - Method of measuring concentration of benzodiazepines in body eluid - Google Patents

Method of measuring concentration of benzodiazepines in body eluid

Info

Publication number
JPS54133193A
JPS54133193A JP649379A JP649379A JPS54133193A JP S54133193 A JPS54133193 A JP S54133193A JP 649379 A JP649379 A JP 649379A JP 649379 A JP649379 A JP 649379A JP S54133193 A JPS54133193 A JP S54133193A
Authority
JP
Japan
Prior art keywords
eluid
benzodiazepines
measuring concentration
concentration
measuring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP649379A
Other languages
English (en)
Inventor
Buresutorupu Kurausu
Efu Sukuwaiaazu Richiyaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia Animal Health Inc
Original Assignee
Ferrosan AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2164/78A external-priority patent/GB1594312A/en
Application filed by Ferrosan AB filed Critical Ferrosan AB
Publication of JPS54133193A publication Critical patent/JPS54133193A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP649379A 1978-05-31 1979-01-19 Method of measuring concentration of benzodiazepines in body eluid Pending JPS54133193A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2164/78A GB1594312A (en) 1977-01-13 1978-05-31 Assaying of drugs in body fluids

Publications (1)

Publication Number Publication Date
JPS54133193A true JPS54133193A (en) 1979-10-16

Family

ID=9734711

Family Applications (1)

Application Number Title Priority Date Filing Date
JP649379A Pending JPS54133193A (en) 1978-05-31 1979-01-19 Method of measuring concentration of benzodiazepines in body eluid

Country Status (7)

Country Link
US (1) US4280993A (ja)
JP (1) JPS54133193A (ja)
DE (1) DE2902071A1 (ja)
DK (1) DK25379A (ja)
FR (1) FR2415303A1 (ja)
NL (1) NL7900458A (ja)
SE (1) SE7900456L (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239744A (en) * 1978-10-10 1980-12-16 United States Of America Radioreceptor assay for benzodiazepines in plasma and other biological specimens
US4375459A (en) * 1980-06-20 1983-03-01 The Regents Of The University Of California Cytoreceptor assay
US4430435A (en) 1980-12-24 1984-02-07 Burroughs Wellcome Co. Assay system
HU187388B (en) * 1981-12-23 1985-12-28 Mta Koezponti Kemiai Kutato In Process and composition for the quantitative determination of substances bound to receptors in the brain and process for preparing the composition
DE3417638A1 (de) * 1984-05-10 1985-11-14 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur bestimmung geringer stoffmengen von arzneimitteln, von koerpereigenen oder anderen chemischen substanzen in biologischem material
US4705758A (en) * 1984-06-19 1987-11-10 Warner-Lambert Company Adenosine receptor assay and kit
USH1209H (en) 1985-10-04 1993-07-06 The United States Of America As Represented By The United States Department Of Energy No-carrier-added (18F)-N-methylspiroperidol
US4869895A (en) * 1986-06-30 1989-09-26 Hoffmann-La Roche Inc. Radiolabeled benzazepine
JPH0780858B2 (ja) * 1987-10-19 1995-08-30 住友化学工業株式会社 放射性ベンゾジアゼピン誘導体およびその製造法
US5216147A (en) * 1987-10-19 1993-06-01 Sumitomo Chemical Company, Limited Radioactive benzodiazepine derivatives
US5597920A (en) * 1992-04-30 1997-01-28 Neurogen Corporation Gabaa receptor subtypes and methods for screening drug compounds using imidazoquinoxalines and pyrrolopyrimidines to bind to gabaa receptor subtypes
US5352585A (en) * 1993-06-29 1994-10-04 Bio-Rad Laboratories, Inc. System for benzodiazepine detection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL226412A (ja) * 1958-03-31
US3338886A (en) * 1961-09-11 1967-08-29 Hoffmann La Roche 5-cycloalkyl-3h-1, 4-benzodiazepin-2(1h)-ones
US3336296A (en) * 1962-10-26 1967-08-15 American Home Prod Preparation of 5-substituted-2h-1, 4-benzodiazepin-2-one-4-oxides
US3546212A (en) * 1968-06-12 1970-12-08 Hoffmann La Roche Oxidation of benzodiazepines with ruthenium tetroxide
US4022878A (en) * 1972-05-15 1977-05-10 Biological Developments, Inc. Methods and compounds for producing specific antibodies
US4083948A (en) * 1977-04-04 1978-04-11 Hoffmann-La Roche, Inc. Benzodiazepine radioimmunoassay using I125-label

Also Published As

Publication number Publication date
FR2415303A1 (fr) 1979-08-17
DK25379A (da) 1979-07-20
SE7900456L (sv) 1979-07-20
DE2902071A1 (de) 1979-07-26
NL7900458A (nl) 1979-07-23
US4280993A (en) 1981-07-28

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