JPS54107589A - Separation and purification of staphylokinase - Google Patents
Separation and purification of staphylokinaseInfo
- Publication number
- JPS54107589A JPS54107589A JP1371778A JP1371778A JPS54107589A JP S54107589 A JPS54107589 A JP S54107589A JP 1371778 A JP1371778 A JP 1371778A JP 1371778 A JP1371778 A JP 1371778A JP S54107589 A JPS54107589 A JP S54107589A
- Authority
- JP
- Japan
- Prior art keywords
- staphylokinase
- purification
- separation
- plasminogen
- medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Enzymes And Modification Thereof (AREA)
Abstract
PURPOSE: To prepare a highly pure staphylokinase useful as a fibrinolytic agent, by the affinity chromatography of microbial product using plasminogen as carrier ligand.
CONSTITUTION: Staphylokinase-producing bacteria, e.g. Staphylococcus aureus RL-TS (ϕ2), are cultured in a medium, and the staphylokinase-containing fraction of the medium is subjected to the affinity chromatography using a carrier having plasminogen to separate the pure staphylokinase.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1371778A JPS54107589A (en) | 1978-02-09 | 1978-02-09 | Separation and purification of staphylokinase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1371778A JPS54107589A (en) | 1978-02-09 | 1978-02-09 | Separation and purification of staphylokinase |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54107589A true JPS54107589A (en) | 1979-08-23 |
JPS5643232B2 JPS5643232B2 (en) | 1981-10-09 |
Family
ID=11840986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1371778A Granted JPS54107589A (en) | 1978-02-09 | 1978-02-09 | Separation and purification of staphylokinase |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54107589A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5867181A (en) * | 1981-10-16 | 1983-04-21 | Yakult Honsha Co Ltd | Novel staphylococcus aureus containing genes that produce staphylokinase and production of staphylokinase |
-
1978
- 1978-02-09 JP JP1371778A patent/JPS54107589A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5867181A (en) * | 1981-10-16 | 1983-04-21 | Yakult Honsha Co Ltd | Novel staphylococcus aureus containing genes that produce staphylokinase and production of staphylokinase |
JPH0478276B2 (en) * | 1981-10-16 | 1992-12-10 | Yakult Honsha Kk |
Also Published As
Publication number | Publication date |
---|---|
JPS5643232B2 (en) | 1981-10-09 |
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