JPS528311B2 - - Google Patents
Info
- Publication number
- JPS528311B2 JPS528311B2 JP47080050A JP8005072A JPS528311B2 JP S528311 B2 JPS528311 B2 JP S528311B2 JP 47080050 A JP47080050 A JP 47080050A JP 8005072 A JP8005072 A JP 8005072A JP S528311 B2 JPS528311 B2 JP S528311B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/10—Preparation of nitro compounds by substitution of functional groups by nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/60—Naphthoxazoles; Hydrogenated naphthoxazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1192671A CH562237A5 (ja) | 1971-08-13 | 1971-08-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS4828464A JPS4828464A (ja) | 1973-04-14 |
| JPS528311B2 true JPS528311B2 (ja) | 1977-03-08 |
Family
ID=4378229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP47080050A Expired JPS528311B2 (ja) | 1971-08-13 | 1972-08-11 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3864333A (ja) |
| JP (1) | JPS528311B2 (ja) |
| AT (1) | AT320632B (ja) |
| AU (1) | AU474787B2 (ja) |
| BE (1) | BE787580A (ja) |
| BR (1) | BR7205493D0 (ja) |
| CA (1) | CA986514A (ja) |
| CH (1) | CH562237A5 (ja) |
| DD (1) | DD101397A5 (ja) |
| DE (1) | DE2238628B2 (ja) |
| DK (1) | DK136717B (ja) |
| ES (1) | ES405653A1 (ja) |
| FR (1) | FR2149489B1 (ja) |
| GB (1) | GB1414670A (ja) |
| IT (1) | IT1049523B (ja) |
| NL (1) | NL7210835A (ja) |
| NO (1) | NO137276C (ja) |
| SE (1) | SE401834B (ja) |
| SU (1) | SU730305A3 (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS588632U (ja) * | 1982-02-09 | 1983-01-20 | 株式会社多田野鉄工所 | 歩み板を有する貨物自動車 |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3781279A (en) * | 1971-02-23 | 1973-12-25 | Sterling Drug Inc | Stilbene optical brighteners |
| US3994879A (en) * | 1972-12-18 | 1976-11-30 | Hoechst Aktiengesellschaft | Process for the preparation of benzofuran compounds |
| DE2306515A1 (de) * | 1973-02-09 | 1974-08-15 | Bayer Ag | Benzo-difuran-verbindungen |
| CH635839A5 (de) | 1976-08-04 | 1983-04-29 | Sandoz Ag | Verfahren zur herstellung von n-substituierten und quaternierten benzimidazolen und deren verwendung. |
| LU78135A1 (de) * | 1977-09-16 | 1979-05-23 | Ciba Geigy Ag | Verfahren zur herstellung von benzodifuranen |
| DE2964427D1 (en) * | 1978-10-04 | 1983-02-03 | Ciba Geigy Ag | Process for the preparation of furanyl-benzazoles |
| DE2904829A1 (de) * | 1979-02-08 | 1980-08-14 | Bayer Ag | Verfahren zur herstellung von benzimidazolylbenzofuran |
| GB8824108D0 (en) * | 1988-10-14 | 1988-11-23 | Unilever Plc | Bleaching & detergent compositions |
| US5326491A (en) * | 1989-04-28 | 1994-07-05 | Ciba-Geigy Corporation | Detergents containing certain sulfonated dibenzofuranylbiphenyls |
| DE102008027972B4 (de) | 2007-07-02 | 2023-06-22 | Merck Patent Gmbh | Naphthofuranderivate |
| HUE035069T2 (en) | 2011-12-28 | 2018-05-02 | Global Blood Therapeutics Inc | Substituted benzaldehyde compounds and their use to increase tissue oxygenation |
| WO2013102145A1 (en) | 2011-12-28 | 2013-07-04 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| US10100043B2 (en) | 2013-03-15 | 2018-10-16 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
| US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| CA2903022C (en) | 2013-03-15 | 2021-11-09 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| KR20150132146A (ko) | 2013-03-15 | 2015-11-25 | 글로벌 블러드 테라퓨틱스, 인크. | 헤모글로빈 조정을 위한 화합물 및 이의 용도 |
| PE20161035A1 (es) | 2013-03-15 | 2016-11-13 | Global Blood Therapeutics Inc | Compuestos y usos de estos para la modulacion de la hemoglobina |
| US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
| EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| JP6809681B2 (ja) | 2014-02-07 | 2021-01-06 | グローバル ブラッド セラピューティクス インコーポレイテッド | ２−ヒドロキシ−６−（（２−（１−イソプロピル−１ｈ−ピラゾール−５−イル）ピリジン−３−イル）メトキシ）ベンズアルデヒドの遊離塩基の結晶多形 |
| MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
| TW201731509A (zh) | 2015-12-04 | 2017-09-16 | 全球血液治療公司 | 針對２-羥基-６-（（２-（１-異丙基-１ｈ-吡唑-５-基）吡啶-３-基）甲氧基）-苯甲醛之劑量方案 |
| TWI663160B (zh) | 2016-05-12 | 2019-06-21 | 全球血液治療公司 | 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法 |
| TW202332423A (zh) | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
| EP3860975B1 (en) | 2018-10-01 | 2023-10-18 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin for the treatment of sickle cell disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH540247A (de) * | 1967-04-21 | 1973-09-28 | Ciba Geigy Ag | Verfahren zur Herstellung von heterocyclischen, Asthylendoppelbindungen enthaltenden Verbindungen |
| FR1537206A (fr) * | 1967-07-21 | 1968-08-23 | Belge Produits Chimiques Sa | Nouveau procédé de préparation de benzofurannes et de formyl-2 benzofurannes |
| CH523909A (de) * | 1969-01-09 | 1972-06-15 | Ciba Geigy Ag | Verfahren zur Herstellung heterocyclischer, Aethylendoppelbindungen enthaltender Verbindungen und deren Verwendung als optische Aufhellmittel ausserhalb der Textilindustrie |
-
0
- BE BE787580D patent/BE787580A/xx unknown
-
1971
- 1971-08-13 CH CH1192671A patent/CH562237A5/xx not_active IP Right Cessation
-
1972
- 1972-08-05 DE DE2238628A patent/DE2238628B2/de not_active Withdrawn
- 1972-08-08 ES ES405653A patent/ES405653A1/es not_active Expired
- 1972-08-08 NL NL7210835A patent/NL7210835A/xx not_active Application Discontinuation
- 1972-08-09 SU SU721819281A patent/SU730305A3/ru active
- 1972-08-10 US US279645A patent/US3864333A/en not_active Expired - Lifetime
- 1972-08-10 AU AU45440/72A patent/AU474787B2/en not_active Expired
- 1972-08-11 IT IT28159/72A patent/IT1049523B/it active
- 1972-08-11 CA CA149212A patent/CA986514A/en not_active Expired
- 1972-08-11 BR BR5493/72A patent/BR7205493D0/pt unknown
- 1972-08-11 GB GB3757672A patent/GB1414670A/en not_active Expired
- 1972-08-11 DD DD165010A patent/DD101397A5/xx unknown
- 1972-08-11 SE SE7210442A patent/SE401834B/xx unknown
- 1972-08-11 NO NO2889/72A patent/NO137276C/no unknown
- 1972-08-11 DK DK398272AA patent/DK136717B/da unknown
- 1972-08-11 AT AT695472A patent/AT320632B/de not_active IP Right Cessation
- 1972-08-11 JP JP47080050A patent/JPS528311B2/ja not_active Expired
- 1972-08-16 FR FR7229327A patent/FR2149489B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS588632U (ja) * | 1982-02-09 | 1983-01-20 | 株式会社多田野鉄工所 | 歩み板を有する貨物自動車 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE787580A (fr) | 1973-02-14 |
| JPS4828464A (ja) | 1973-04-14 |
| BR7205493D0 (pt) | 1973-09-20 |
| SU730305A3 (ru) | 1980-04-25 |
| IT1049523B (it) | 1981-02-10 |
| GB1414670A (en) | 1975-11-19 |
| DE2238628A1 (de) | 1973-03-29 |
| SE401834B (sv) | 1978-05-29 |
| US3864333A (en) | 1975-02-04 |
| DD101397A5 (ja) | 1973-11-05 |
| DK136717C (ja) | 1978-05-01 |
| NO137276B (no) | 1977-10-24 |
| FR2149489B1 (ja) | 1977-12-23 |
| AT320632B (de) | 1975-02-25 |
| NL7210835A (ja) | 1973-02-15 |
| NO137276C (no) | 1978-02-01 |
| CH562237A5 (ja) | 1975-05-30 |
| AU474787B2 (en) | 1976-08-05 |
| AU4544072A (en) | 1974-02-14 |
| FR2149489A1 (ja) | 1973-03-30 |
| DK136717B (da) | 1977-11-14 |
| DE2238628B2 (de) | 1978-10-26 |
| ES405653A1 (es) | 1975-07-01 |
| CA986514A (en) | 1976-03-30 |