JPS5268186A - Picolinic acid derivatives and their preparation - Google Patents

Picolinic acid derivatives and their preparation

Info

Publication number
JPS5268186A
JPS5268186A JP51141073A JP14107376A JPS5268186A JP S5268186 A JPS5268186 A JP S5268186A JP 51141073 A JP51141073 A JP 51141073A JP 14107376 A JP14107376 A JP 14107376A JP S5268186 A JPS5268186 A JP S5268186A
Authority
JP
Japan
Prior art keywords
preparation
acid derivatives
picolinic acid
picolinic
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51141073A
Other languages
English (en)
Japanese (ja)
Inventor
Heigaa Shiyaarots Maagaretsuto
Roobuku Haido
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD International Holdings GmbH
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/636,010 external-priority patent/US4044140A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of JPS5268186A publication Critical patent/JPS5268186A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP51141073A 1975-11-28 1976-11-24 Picolinic acid derivatives and their preparation Pending JPS5268186A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63600975A 1975-11-28 1975-11-28
US05/636,010 US4044140A (en) 1975-11-28 1975-11-28 Trityl picolinic acid derivatives and their use as anti-acne agents

Publications (1)

Publication Number Publication Date
JPS5268186A true JPS5268186A (en) 1977-06-06

Family

ID=27092506

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51141073A Pending JPS5268186A (en) 1975-11-28 1976-11-24 Picolinic acid derivatives and their preparation

Country Status (13)

Country Link
JP (1) JPS5268186A (enExample)
AR (1) AR223803A1 (enExample)
AU (1) AU506351B2 (enExample)
CH (1) CH629488A5 (enExample)
DE (1) DE2653138A1 (enExample)
DK (1) DK526976A (enExample)
FR (1) FR2332753A1 (enExample)
GB (1) GB1565056A (enExample)
GR (1) GR61662B (enExample)
HU (1) HU175179B (enExample)
NL (1) NL7613041A (enExample)
PT (1) PT65874B (enExample)
SE (1) SE7613090L (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020519601A (ja) * 2017-05-10 2020-07-02 ダウ アグロサイエンシィズ エルエルシー ４−アミノ−６−（複素環）ピコリネート、および６−アミノ−２−（複素環）ピリミジン−４−カルボキシレート、および除草剤としてのそれらの使用
US12285012B2 (en) 2018-11-07 2025-04-29 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with acetolactate synthase (ALS) inhibitor herbicides

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4555520A (en) * 1984-08-20 1985-11-26 E. R. Squibb & Sons, Inc. 2-Pyridylcarboxamides which inhibit arachidonic acid release
US5501329A (en) * 1995-04-05 1996-03-26 Provence; Daniel J. Telephone handset cover
US6579891B1 (en) 1995-12-29 2003-06-17 Novactyl, Inc. Agent and method for prevention and treatment of cancer in animals
US6407125B1 (en) 1995-12-29 2002-06-18 Novactyl, Inc. Pharmacological agent and method of treatment
US6743771B2 (en) 1995-12-29 2004-06-01 Novactyl, Inc. Methods and compositions for controlling protein assembly or aggregation
US6441009B1 (en) 1998-08-01 2002-08-27 Novactyl, Inc. Agent and method of preventing and treating heavy metal exposure and toxicity
US6403618B1 (en) 2000-02-15 2002-06-11 Novactyl, Inc. Agent and method for controlling angiogenesis
RU2272028C2 (ru) * 2004-06-04 2006-03-20 Григорьев Лев Викторович Способ получения тетрахлорпиколиновой кислоты
RU2273635C2 (ru) * 2004-06-04 2006-04-10 Григорьев Лев Викторович Способ получения тетрахлорпиколиновой кислоты
US12310364B2 (en) 2018-11-06 2025-05-27 Corteva Agriscience Llc Safened compositions comprising pyridine carboxylate herbicides and cloquintocet
UA128373C2 (uk) 2018-11-06 2024-06-26 Кортева Аґрисайєнс Елелсі Композиції з антидотом, які містять гербіциди на основі піридинкарбоксилату та ізоксадифен
LT3876726T (lt) 2018-11-06 2025-03-10 Corteva Agriscience Llc Kompozicijos, apimančios piridino karboksilato herbicidus ir azolo karboksilato herbicidų antidotus
EP3876733B1 (en) 2018-11-07 2025-07-02 Corteva Agriscience LLC Compositions comprising pyridine carboxylate herbicides with photosystem ii and optional hppd inhibitor herbicides
DK3876729T3 (da) 2018-11-07 2025-03-31 Corteva Agriscience Llc Sammensætninger, som omfatter et pyridincarboxylatherbicid og protoporphyrinogenoxidase (protox)-hæmmerherbicider
PL3876730T3 (pl) 2018-11-07 2025-11-03 Corteva Agriscience Llc Kompozycje zawierające herbicydy pirydynokarboksylanowe oraz herbicydy będące inhibitorami dioksygenazy 4-hydroksyfenylo- pirogronianowej (hppd)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020519601A (ja) * 2017-05-10 2020-07-02 ダウ アグロサイエンシィズ エルエルシー ４−アミノ−６−（複素環）ピコリネート、および６−アミノ−２−（複素環）ピリミジン−４−カルボキシレート、および除草剤としてのそれらの使用
US12285012B2 (en) 2018-11-07 2025-04-29 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with acetolactate synthase (ALS) inhibitor herbicides

Also Published As

Publication number Publication date
AR223803A1 (es) 1981-09-30
HU175179B (hu) 1980-05-28
PT65874A (en) 1976-12-01
CH629488A5 (en) 1982-04-30
AU506351B2 (en) 1979-12-20
DK526976A (da) 1977-05-29
GR61662B (en) 1978-12-05
NL7613041A (nl) 1977-06-01
GB1565056A (en) 1980-04-16
FR2332753A1 (fr) 1977-06-24
FR2332753B1 (enExample) 1978-11-17
PT65874B (en) 1978-05-17
SE7613090L (sv) 1977-05-29
AU1993576A (en) 1978-06-01
DE2653138A1 (de) 1977-06-08

Similar Documents

Publication Publication Date Title
AU1934876A (en) Hydroxybenzylmalonic acid derivatives
NZ182908A (en) 2-tertiaryaminoindol-3-ylcarboxylic acid derivatives
JPS5268186A (en) Picolinic acid derivatives and their preparation
GB1538240A (en) O-2-isocephem compounds and their preparation
MY8100161A (en) Hydroxybenzylmalonic acid derivatives
NZ182021A (en) Phenoxyalkylcarboxylic acid derivatives and pharmaceuticalcompositions
IL50159A0 (en) Novel pyridine derivatives and their preparation
IL49516A (en) 3-amino-4-deoxo-4-imino and amino-rifamycins and their preparation
IL50657A (en) 11-deoxy-16-aryl- -tetranor-prosta-cis-5-ene-13-yneoic acid derivatives and their preparation
AU499080B2 (en) Ortho-aminobutyrophenone derivatives and salts thereof
ZA767103B (en) Picolinic acid derivatives and processes for their preparation
JPS51113884A (en) Pyri midinylurea and preparation method
JPS5212175A (en) Triazaspirodecanone derivatives and preparation method thereof
JPS5217478A (en) New homophthalimide derivatives and preparation method thereof
JPS5251364A (en) Thiazolizine derivatives and preparation thereof
ZA763812B (en) D1-and 8r-9-fluoro-prostadienoic acid derivatives and process
JPS523060A (en) Paraachlorophenoxyisobutyric acid derivatives and preparation thereof
JPS5219650A (en) Novel diaminooandrostane derivatives * acid adduct salts * quartanary salts and preparation thereof
JPS51125338A (en) Diphenylether derivatives and preparation thereof
IE43457L (en) 1-deoxyribofuranuronic acid derivatives
JPS5212177A (en) Azanaphthaleneacetic acid derivatives
GB1545467A (en) Deoxyclavulanic acid and deoxyisoclavulanic acid and derivatives thereof
GB1535373A (en) Prostenoic acid derivatives
JPS51131868A (en) Benzobicyclonene derivatives and preparation thereof
JPS51146475A (en) New quinoline derivatives preparation method and uses