JPS5259192A - Preparation of 2,6-bis(diethanolamino)_4,8-dipiperidino-pyrimido 5,4-d pyrimidines - Google Patents
Preparation of 2,6-bis(diethanolamino)_4,8-dipiperidino-pyrimido 5,4-d pyrimidinesInfo
- Publication number
- JPS5259192A JPS5259192A JP13550175A JP13550175A JPS5259192A JP S5259192 A JPS5259192 A JP S5259192A JP 13550175 A JP13550175 A JP 13550175A JP 13550175 A JP13550175 A JP 13550175A JP S5259192 A JPS5259192 A JP S5259192A
- Authority
- JP
- Japan
- Prior art keywords
- dipiperidino
- diethanolamino
- pyrimido
- pyrimidines
- bis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 239000003218 coronary vasodilator agent Substances 0.000 abstract 1
- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 abstract 1
- 229960002768 dipyridamole Drugs 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PURPOSE: Dipyridamole useful as coronary vasodilator is easily prepared by hydrolysis of a novel intermediate.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13550175A JPS5259192A (en) | 1975-11-10 | 1975-11-10 | Preparation of 2,6-bis(diethanolamino)_4,8-dipiperidino-pyrimido 5,4-d pyrimidines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13550175A JPS5259192A (en) | 1975-11-10 | 1975-11-10 | Preparation of 2,6-bis(diethanolamino)_4,8-dipiperidino-pyrimido 5,4-d pyrimidines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5259192A true JPS5259192A (en) | 1977-05-16 |
| JPS5714678B2 JPS5714678B2 (en) | 1982-03-25 |
Family
ID=15153217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13550175A Granted JPS5259192A (en) | 1975-11-10 | 1975-11-10 | Preparation of 2,6-bis(diethanolamino)_4,8-dipiperidino-pyrimido 5,4-d pyrimidines |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5259192A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002523450A (en) * | 1998-09-01 | 2002-07-30 | ニトロメド インコーポレーテッド | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3074928A (en) * | 1959-06-25 | 1963-01-22 | Thomae Gmbh Dr K | Basic-substituted pyrimido-[5,4-d]-pyrimidines |
| JPS50101391A (en) * | 1974-01-25 | 1975-08-11 |
-
1975
- 1975-11-10 JP JP13550175A patent/JPS5259192A/en active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3074928A (en) * | 1959-06-25 | 1963-01-22 | Thomae Gmbh Dr K | Basic-substituted pyrimido-[5,4-d]-pyrimidines |
| JPS50101391A (en) * | 1974-01-25 | 1975-08-11 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002523450A (en) * | 1998-09-01 | 2002-07-30 | ニトロメド インコーポレーテッド | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5714678B2 (en) | 1982-03-25 |
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