JPS5259186A - Preparation of 3-cephem compounds by reduction - Google Patents
Preparation of 3-cephem compounds by reductionInfo
- Publication number
- JPS5259186A JPS5259186A JP50135385A JP13538575A JPS5259186A JP S5259186 A JPS5259186 A JP S5259186A JP 50135385 A JP50135385 A JP 50135385A JP 13538575 A JP13538575 A JP 13538575A JP S5259186 A JPS5259186 A JP S5259186A
- Authority
- JP
- Japan
- Prior art keywords
- reduction
- preparation
- cephem compounds
- cephem
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FZEVMBJWXHDLDB-ZCFIWIBFSA-N (6r)-5-thia-1-azabicyclo[4.2.0]oct-2-en-8-one Chemical class S1CC=CN2C(=O)C[C@H]21 FZEVMBJWXHDLDB-ZCFIWIBFSA-N 0.000 title 1
- XSBHBYCNRIIYDF-BAFYGKSASA-N (6r)-4-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical class OC(=O)C1=CC(N)S[C@@H]2CC(=O)N21 XSBHBYCNRIIYDF-BAFYGKSASA-N 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50135385A JPS5259186A (en) | 1975-11-11 | 1975-11-11 | Preparation of 3-cephem compounds by reduction |
| CA264,971A CA1069119A (en) | 1975-11-11 | 1976-11-05 | Reduction giving 3-cephem compounds |
| FR7634020A FR2331564A1 (fr) | 1975-11-11 | 1976-11-10 | Procede de reduction donnant des composes de 3-cephem et nouveaux produits ainsi obtenus |
| CH1423576A CH606005A5 (enExample) | 1975-11-11 | 1976-11-11 | |
| US05/740,967 US4081595A (en) | 1975-11-11 | 1976-11-11 | Reduction giving 3-cephem compounds |
| DE2651509A DE2651509C2 (de) | 1975-11-11 | 1976-11-11 | Verfahren zur Herstellung von 3-Cephemverbindungen |
| GB47100/76A GB1529598A (en) | 1975-11-11 | 1976-11-11 | Preparation of 3-cephem compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50135385A JPS5259186A (en) | 1975-11-11 | 1975-11-11 | Preparation of 3-cephem compounds by reduction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5259186A true JPS5259186A (en) | 1977-05-16 |
| JPS611434B2 JPS611434B2 (enExample) | 1986-01-17 |
Family
ID=15150459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50135385A Granted JPS5259186A (en) | 1975-11-11 | 1975-11-11 | Preparation of 3-cephem compounds by reduction |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4081595A (enExample) |
| JP (1) | JPS5259186A (enExample) |
| CA (1) | CA1069119A (enExample) |
| CH (1) | CH606005A5 (enExample) |
| DE (1) | DE2651509C2 (enExample) |
| FR (1) | FR2331564A1 (enExample) |
| GB (1) | GB1529598A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997047627A1 (en) * | 1996-06-13 | 1997-12-18 | Otsuka Kagaku Kabushiki Kaisha | Process for producing 3-norcephem compounds |
| WO2014069649A1 (en) * | 2012-10-29 | 2014-05-08 | Shionogi & Co., Ltd. | Processes for production of intermediates for 2-alkyl cephem compounds |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS543087A (en) * | 1977-06-03 | 1979-01-11 | Fujisawa Pharmaceut Co Ltd | Preparation of cephalosporin compound |
| US4402803A (en) * | 1981-09-14 | 1983-09-06 | Eli Lilly And Company | Process for 3-hydrogen cephems |
| CN105315299B (zh) * | 2015-09-22 | 2017-06-27 | 盐城开元医药化工有限公司 | 一种头孢唑肟母核7‑anca的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929775A (en) * | 1970-12-08 | 1975-12-30 | Takeda Chemical Industries Ltd | Process for producing cephalosporin derivatives |
| US3883518A (en) * | 1972-05-15 | 1975-05-13 | Merck & Co Inc | 3-Methylene cephalosporins |
-
1975
- 1975-11-11 JP JP50135385A patent/JPS5259186A/ja active Granted
-
1976
- 1976-11-05 CA CA264,971A patent/CA1069119A/en not_active Expired
- 1976-11-10 FR FR7634020A patent/FR2331564A1/fr active Granted
- 1976-11-11 CH CH1423576A patent/CH606005A5/xx not_active IP Right Cessation
- 1976-11-11 GB GB47100/76A patent/GB1529598A/en not_active Expired
- 1976-11-11 US US05/740,967 patent/US4081595A/en not_active Expired - Lifetime
- 1976-11-11 DE DE2651509A patent/DE2651509C2/de not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997047627A1 (en) * | 1996-06-13 | 1997-12-18 | Otsuka Kagaku Kabushiki Kaisha | Process for producing 3-norcephem compounds |
| US5977352A (en) * | 1996-06-13 | 1999-11-02 | Otsuka Kagaku Kabushiki Kaisha | Process for preparing 3-norcephem compounds |
| CN1098268C (zh) * | 1996-06-13 | 2003-01-08 | 大塚化学株式会社 | 3-头孢烯化合物的制备方法 |
| WO2014069649A1 (en) * | 2012-10-29 | 2014-05-08 | Shionogi & Co., Ltd. | Processes for production of intermediates for 2-alkyl cephem compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1069119A (en) | 1980-01-01 |
| US4081595A (en) | 1978-03-28 |
| FR2331564B1 (enExample) | 1979-02-23 |
| CH606005A5 (enExample) | 1978-10-13 |
| FR2331564A1 (fr) | 1977-06-10 |
| DE2651509A1 (de) | 1977-05-18 |
| DE2651509C2 (de) | 1986-07-17 |
| JPS611434B2 (enExample) | 1986-01-17 |
| GB1529598A (en) | 1978-10-25 |
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