JPS52151718A - Production of capsulated hemoglobin - Google Patents

Production of capsulated hemoglobin

Info

Publication number
JPS52151718A
JPS52151718A JP6836877A JP6836877A JPS52151718A JP S52151718 A JPS52151718 A JP S52151718A JP 6836877 A JP6836877 A JP 6836877A JP 6836877 A JP6836877 A JP 6836877A JP S52151718 A JPS52151718 A JP S52151718A
Authority
JP
Japan
Prior art keywords
capsulated
hemoglobin
production
capsulated hemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6836877A
Other languages
Japanese (ja)
Other versions
JPS6026092B2 (en
Inventor
Furankurin Miraa Aabiingu
Jiyorujiebuichi Riyubomiiru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois
Original Assignee
University of Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Illinois filed Critical University of Illinois
Publication of JPS52151718A publication Critical patent/JPS52151718A/en
Publication of JPS6026092B2 publication Critical patent/JPS6026092B2/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]
JP52068368A 1976-06-10 1977-06-09 Encapsulated hemoglobin and its production method Expired JPS6026092B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69490376A 1976-06-10 1976-06-10
US694903 1976-06-10

Publications (2)

Publication Number Publication Date
JPS52151718A true JPS52151718A (en) 1977-12-16
JPS6026092B2 JPS6026092B2 (en) 1985-06-21

Family

ID=24790735

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52068368A Expired JPS6026092B2 (en) 1976-06-10 1977-06-09 Encapsulated hemoglobin and its production method

Country Status (8)

Country Link
US (1) US4133874A (en)
JP (1) JPS6026092B2 (en)
BE (1) BE855481A (en)
CA (1) CA1095444A (en)
DE (1) DE2725696A1 (en)
FR (1) FR2354095A1 (en)
GB (1) GB1578776A (en)
NL (1) NL7706417A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58183625A (en) * 1982-04-02 1983-10-26 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア Enzyme transfer system
JPS60243022A (en) * 1984-04-09 1985-12-03 サンド・アクチエンゲゼルシヤフト Improvement on interleukin therapy
JPS6137735A (en) * 1984-07-31 1986-02-22 Terumo Corp Hemoglobin-containing liposome and its preparation
JPS61501513A (en) * 1984-03-23 1986-07-24 バイオコンパテイブルズ・リミテッド Improvements related to gas transport
JPS63211230A (en) * 1987-02-27 1988-09-02 Terumo Corp Hemoglobin-containing liposome
JPH01180245A (en) * 1988-01-12 1989-07-18 Terumo Corp Liposome
JPH0286841A (en) * 1988-09-26 1990-03-27 Terumo Corp Liposome and production thereof
JPH02121932A (en) * 1988-10-29 1990-05-09 Res Inst For Prod Dev Hemoglobin-containing liposome, preparation thereof and raw solution for same preparation
US6710038B1 (en) 1999-12-14 2004-03-23 Kibun Food Chemifa Co., Ltd. Emulsification method using propylene glycol hyaluronate

Families Citing this family (81)

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US4390521A (en) * 1980-04-11 1983-06-28 Exxon Research And Engineering Co. Artificial red cells
US4376059A (en) * 1980-04-11 1983-03-08 Exxon Research And Engineering Co. Process for preparing artificial red cells
US4469792A (en) * 1980-12-31 1984-09-04 Allied Corporation Blood gas calibration and control fluid utilizing stroma-free hemoglobin
WO1983000089A1 (en) * 1981-07-06 1983-01-20 Rush Presbyterian St Luke Preparation of synthetic erythrocytes
US4558032A (en) * 1981-12-31 1985-12-10 Neomed Inc. Synthetic whole blood substitute and a method of making the same
US4547490A (en) * 1981-12-31 1985-10-15 Neomed, Inc. Synthetic whole blood and a method of making the same
US4612370A (en) * 1982-04-02 1986-09-16 The Regents Of The University Of California Lipid-saccharide reaction products
US4423077A (en) * 1982-07-27 1983-12-27 The University Of Pennsylvania Perfluorochemical emulsion artificial blood
US4497829A (en) * 1982-07-27 1985-02-05 The University Of Pennsylvania Process for preparing perfluorochemical emulsion artificial blood
US4397870A (en) * 1982-07-27 1983-08-09 The University Of Pennsylvania Process for prolonging retention of emulsion particles in the bloodstream
EP0223906A3 (en) * 1982-10-29 1989-02-01 Synthetic Blood Corporation Gelatin based synthetic whole blood and a process for preparing the same
US4530794A (en) * 1982-12-01 1985-07-23 Taiho Pharmaceutical Co., Ltd. Iron-tetraphenylporphine complex having phosphocholine group
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
US4853370A (en) * 1984-04-27 1989-08-01 Synthetic Blood Corporation Substitute for human blood and a method of making the same
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4738952A (en) * 1984-04-27 1988-04-19 Synthetic Blood Corporation Substitute for human blood and a method of making the same
US4622188A (en) * 1984-12-21 1986-11-11 E. I. Du Pont De Nemours And Company Method for manufacturing liposomes
US4737276A (en) * 1984-12-21 1988-04-12 E. I. Du Pont De Nemours And Company Apparatus for manufacturing liposomes
JPS61155336A (en) * 1984-12-28 1986-07-15 Terumo Corp Medical carrier
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
CA1312009C (en) * 1986-11-10 1992-12-29 Carl W. Rausch Extra pure semi-synthetic blood substitute
US5049391A (en) * 1987-02-27 1991-09-17 Terumo Kabushiki Kaisha Liposome encapsulated hemoglobin
JPS63211222A (en) * 1987-02-27 1988-09-02 Terumo Corp Production of liposome
US4855090A (en) * 1987-03-13 1989-08-08 Micro-Pak, Inc. Method of producing high aqueous volume multilamellar vesicles
US4942038A (en) * 1987-03-13 1990-07-17 Micro Vesicular Systems, Inc. Encapsulated humectant
US5628936A (en) * 1987-03-13 1997-05-13 Micro-Pak, Inc. Hybrid paucilamellar lipid vesicles
US5023086A (en) * 1987-03-13 1991-06-11 Micro-Pak, Inc. Encapsulated ionophore growth factors
US5234767A (en) * 1987-03-13 1993-08-10 Micro-Pak, Inc. Hybrid paucilamellar lipid vesicles
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles
US5000960A (en) * 1987-03-13 1991-03-19 Micro-Pak, Inc. Protein coupling to lipid vesicles
US4917951A (en) * 1987-07-28 1990-04-17 Micro-Pak, Inc. Lipid vesicles formed of surfactants and steroids
US4853228A (en) * 1987-07-28 1989-08-01 Micro-Pak, Inc. Method of manufacturing unilamellar lipid vesicles
US5104736A (en) * 1988-03-03 1992-04-14 Micro-Pak, Inc. Reinforced paucilamellar lipid vesicles
US5019392A (en) * 1988-03-03 1991-05-28 Micro-Pak, Inc. Encapsulation of parasiticides
US5160669A (en) * 1988-03-03 1992-11-03 Micro Vesicular Systems, Inc. Method of making oil filled paucilamellar lipid vesicles
US5019174A (en) * 1988-03-03 1991-05-28 Micro Vesicular Systems, Inc. Removing oil from surfaces with liposomal cleaner
JPH0720857B2 (en) * 1988-08-11 1995-03-08 テルモ株式会社 Liposome and its manufacturing method
FR2641463B1 (en) * 1989-01-09 1991-03-08 Sederma Sa COSMETIC PREPARATIONS FOR OXYGENATION OF THE SKIN
US4935171A (en) * 1989-01-27 1990-06-19 Vestar, Inc. Method for vesicle formation
US5139803A (en) * 1989-02-09 1992-08-18 Nabisco, Inc. Method and liposome composition for the stabilization of oxidizable substances
US5015483A (en) * 1989-02-09 1991-05-14 Nabisco Brands, Inc. Liposome composition for the stabilization of oxidizable substances
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
US5284663A (en) * 1991-07-23 1994-02-08 Temple University Salt film encapsulated perfluorocarbons
EP0615747B1 (en) * 1993-03-18 1999-09-29 Terumo Kabushiki Kaisha Hemoglobin-encapsulating liposome and method for making the same
US5674528A (en) * 1994-06-15 1997-10-07 Terumo Kabushiki Kaisha Hemoglobin-encapsulated liposome
US5589189A (en) * 1994-09-14 1996-12-31 Nexstar Pharmaceuticals, Inc. Liposome dispersion
JP5038552B2 (en) 1995-10-17 2012-10-03 オバン・エナジー・リミテッド Insoluble drug delivery
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US5814601A (en) * 1997-02-28 1998-09-29 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
US6054427A (en) * 1997-02-28 2000-04-25 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
US7687272B1 (en) 1998-01-12 2010-03-30 Henry Buchwald Method and apparatus for determining blood oxygen transport
US6037181A (en) * 1998-01-12 2000-03-14 Buchwald; Henry Method and apparatus for determining blood oxygen transport
ES2201673T3 (en) * 1998-02-11 2004-03-16 Rtp Pharma Corporation COMBINATION OF STEROIDS AND POIINSATURED FATTY ACIDS FOR THE TREATMENT OF INFLAMMATORY STATES.
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
AU764001B2 (en) 1998-05-29 2003-08-07 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
EP1105096B1 (en) * 1998-08-19 2003-10-29 Skyepharma Canada Inc. Injectable aqueous dispersions of propofol
JP4809533B2 (en) 1998-11-20 2011-11-09 オバン・エナジー・リミテッド Dispersible phospholipid stabilized microparticles
US6806091B1 (en) 1999-01-12 2004-10-19 Henry Buchwald Method and apparatus for determining blood oxygen transport
ATE296091T1 (en) * 1999-09-21 2005-06-15 Skyepharma Canada Inc SURFACE-MODIFIED PARTICLE COMPOSITIONS OF BIOLOGICALLY ACTIVE SUBSTANCES
US6500809B1 (en) 1999-11-12 2002-12-31 Neuron Therapeutics, Inc. Hyperoncotic artificial cerebrospinal fluid and method of treating neural tissue edema therewith
JP5102423B2 (en) 2000-04-20 2012-12-19 オバン・エナジー・リミテッド Improved treatment of water-insoluble drug particles
ATE424811T1 (en) 2000-08-31 2009-03-15 Jagotec Ag GROUND PARTICLES
NZ525231A (en) * 2000-09-20 2004-08-27 Skyepharma Canada Inc Phospholipid stabilised feno-fibrate microparticles for pharmaceutical use
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
US6534088B2 (en) * 2001-02-22 2003-03-18 Skyepharma Canada Inc. Fibrate-statin combinations with reduced fed-fasted effects
HUP0101713A2 (en) * 2001-04-27 2003-02-28 István Horváth Process for the preparation of artificial blood
US20030153491A1 (en) * 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20050164915A1 (en) * 2002-04-01 2005-07-28 Sangart, Inc. Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20050287125A1 (en) * 2002-05-22 2005-12-29 Medtronic, Inc. Cell delivery fluid for prevention of cell settling in delivery system
JP3912206B2 (en) * 2002-07-05 2007-05-09 株式会社日立製作所 Fuel pump for in-cylinder direct fuel injection system
HU226519B1 (en) * 2002-11-26 2009-03-30 Istvan Dr Horvath Artificial blood made of hemoglobin encapsulated in membrane
CU23313A1 (en) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia MÃ0 / 00 METHOD OF OBTAINING COCLEAR STRUCTURES VACCINAL COMPOSITIONS AND ADJUSTS BASED ON COCLEAR STRUCTURES AND THEIR INTERMEDIARIES
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DE102008043751B4 (en) * 2008-11-14 2013-09-26 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Process for the preparation of large vesicles from self-assembling, membrane-forming molecules
US20140134597A1 (en) * 2012-11-15 2014-05-15 Bio-Rad Laboratories, Inc. Cellular hemoglobin a1c quality controls

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DE2248475C3 (en) * 1972-10-03 1978-09-28 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Process for obtaining hepatic-safe, storage-stable and infusable hemoglobin solutions
US3887698A (en) * 1973-03-12 1975-06-03 Univ Leland Stanford Junior Sacs with epitopic sites on walls enclosing stable free radicals
CH588887A5 (en) * 1974-07-19 1977-06-15 Battelle Memorial Institute

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58183625A (en) * 1982-04-02 1983-10-26 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア Enzyme transfer system
JPS61501513A (en) * 1984-03-23 1986-07-24 バイオコンパテイブルズ・リミテッド Improvements related to gas transport
JPS60243022A (en) * 1984-04-09 1985-12-03 サンド・アクチエンゲゼルシヤフト Improvement on interleukin therapy
JPS6137735A (en) * 1984-07-31 1986-02-22 Terumo Corp Hemoglobin-containing liposome and its preparation
JPH0474338B2 (en) * 1984-07-31 1992-11-26
JPS63211230A (en) * 1987-02-27 1988-09-02 Terumo Corp Hemoglobin-containing liposome
JPH01180245A (en) * 1988-01-12 1989-07-18 Terumo Corp Liposome
JPH0286841A (en) * 1988-09-26 1990-03-27 Terumo Corp Liposome and production thereof
JPH02121932A (en) * 1988-10-29 1990-05-09 Res Inst For Prod Dev Hemoglobin-containing liposome, preparation thereof and raw solution for same preparation
US6710038B1 (en) 1999-12-14 2004-03-23 Kibun Food Chemifa Co., Ltd. Emulsification method using propylene glycol hyaluronate

Also Published As

Publication number Publication date
BE855481A (en) 1977-12-07
NL7706417A (en) 1977-12-13
DE2725696A1 (en) 1977-12-22
CA1095444A (en) 1981-02-10
GB1578776A (en) 1980-11-12
FR2354095A1 (en) 1978-01-06
US4133874A (en) 1979-01-09
JPS6026092B2 (en) 1985-06-21
FR2354095B1 (en) 1980-04-25

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