JPS52122396A - Xanthin compound and and agent for controlling bronchus convulsions and allergy - Google Patents

Xanthin compound and and agent for controlling bronchus convulsions and allergy

Info

Publication number
JPS52122396A
JPS52122396A JP3555977A JP3555977A JPS52122396A JP S52122396 A JPS52122396 A JP S52122396A JP 3555977 A JP3555977 A JP 3555977A JP 3555977 A JP3555977 A JP 3555977A JP S52122396 A JPS52122396 A JP S52122396A
Authority
JP
Japan
Prior art keywords
xanthin
bronchus
convulsions
allergy
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3555977A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5720313B2 (pt
Inventor
Daiamondo Jiyuriasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cooper Laboratories Inc
Original Assignee
Cooper Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/672,437 external-priority patent/US4089959A/en
Priority claimed from US05/672,388 external-priority patent/US4120947A/en
Application filed by Cooper Laboratories Inc filed Critical Cooper Laboratories Inc
Publication of JPS52122396A publication Critical patent/JPS52122396A/ja
Publication of JPS5720313B2 publication Critical patent/JPS5720313B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP3555977A 1976-03-31 1977-03-31 Xanthin compound and and agent for controlling bronchus convulsions and allergy Granted JPS52122396A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/672,437 US4089959A (en) 1976-03-31 1976-03-31 Long-acting xanthine bronchodilators and antiallergy agents
US05/672,388 US4120947A (en) 1976-03-31 1976-03-31 Xanthine compounds and method of treating bronchospastic and allergic diseases

Publications (2)

Publication Number Publication Date
JPS52122396A true JPS52122396A (en) 1977-10-14
JPS5720313B2 JPS5720313B2 (pt) 1982-04-27

Family

ID=27100746

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3555977A Granted JPS52122396A (en) 1976-03-31 1977-03-31 Xanthin compound and and agent for controlling bronchus convulsions and allergy

Country Status (5)

Country Link
JP (1) JPS52122396A (pt)
CA (1) CA1077932A (pt)
DE (1) DE2713389A1 (pt)
FR (1) FR2346353A1 (pt)
GB (1) GB1561005A (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56166191A (en) * 1980-04-18 1981-12-21 Draco Ab 3,8-dialkylxanthines and manufacture
JPS56169690A (en) * 1980-05-02 1981-12-26 Nestle Sa Xanthinederivative and manufacture
JPH0130834B2 (pt) * 1978-10-20 1989-06-22 Draco Ab

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416810C (sv) 1977-10-14 1982-07-19 Draco Ab Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
SE7810946L (sv) * 1978-10-20 1980-04-21 Draco Ab Metod att behandla kronisk obstruktiv luftvegssjukdom
FR2611716A1 (fr) * 1987-03-06 1988-09-09 Uriach Cia Sa J Derives de diisobutylxanthine substituee en position 7 utiles comme bronchodilatateurs, procede pour leur preparation et composition pharmaceutique les contenant
US5321029A (en) * 1988-11-14 1994-06-14 Beecham-Wuelfing Gmbh & Co.K.G. Xanthines
GB8826595D0 (en) * 1988-11-14 1988-12-21 Beecham Wuelfing Gmbh & Co Kg Active compounds
IT1229195B (it) * 1989-03-10 1991-07-25 Poli Ind Chimica Spa Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US6066641A (en) * 1994-12-13 2000-05-23 Euro-Celtique S.A. Aryl thioxanthines
DE69531555T2 (de) 1994-12-13 2004-06-17 Euroceltique S.A. Dreifachsubstituierte thioxanthine
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2729643A (en) * 1956-01-03 J-disubstmjied and i

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MOL. PARMACOL.#V6#N6=1970 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0130834B2 (pt) * 1978-10-20 1989-06-22 Draco Ab
JPS56166191A (en) * 1980-04-18 1981-12-21 Draco Ab 3,8-dialkylxanthines and manufacture
JPS56169690A (en) * 1980-05-02 1981-12-26 Nestle Sa Xanthinederivative and manufacture

Also Published As

Publication number Publication date
DE2713389A1 (de) 1977-10-13
JPS5720313B2 (pt) 1982-04-27
FR2346353A1 (fr) 1977-10-28
DE2713389C2 (pt) 1992-03-19
FR2346353B1 (pt) 1980-03-07
GB1561005A (en) 1980-02-13
CA1077932A (en) 1980-05-20

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