JPS52108980A - Carbostyril derivatives and their preparation - Google Patents
Carbostyril derivatives and their preparationInfo
- Publication number
- JPS52108980A JPS52108980A JP2449276A JP2449276A JPS52108980A JP S52108980 A JPS52108980 A JP S52108980A JP 2449276 A JP2449276 A JP 2449276A JP 2449276 A JP2449276 A JP 2449276A JP S52108980 A JPS52108980 A JP S52108980A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- carbostyril derivatives
- lower alkyl
- alkenyl
- carbostyril
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: Carbostyril derivatives of the formula I (R is H, lower alkyl or alkenyl, etc.; R2 is H, or lower alkyl, alkenyl or cycloalkyl; R3 and R4 are H, or lower alkyl; X is O, S, or imino; Y is hydroxyl, lower alkoxy, amino, phenyl, etc.; l is 0 or 1 ; and m and n are 0 or integers of 1W3), or their salts. For example, 5-[3-(3, 4-dimethoxyphenethylamino)-2-hydroxy] propoxy-3, 4dihydrocarbostyril may be cited.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51024492A JPS5936617B2 (en) | 1976-03-05 | 1976-03-05 | carbostyril derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51024492A JPS5936617B2 (en) | 1976-03-05 | 1976-03-05 | carbostyril derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS52108980A true JPS52108980A (en) | 1977-09-12 |
JPS5936617B2 JPS5936617B2 (en) | 1984-09-05 |
Family
ID=12139667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51024492A Expired JPS5936617B2 (en) | 1976-03-05 | 1976-03-05 | carbostyril derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5936617B2 (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63290821A (en) * | 1987-05-25 | 1988-11-28 | Otsuka Pharmaceut Co Ltd | Antiarrhythmic |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
WO1992017178A1 (en) * | 1991-04-03 | 1992-10-15 | Otsuka Pharmaceutical Company, Limited | Remedy for thrombosis and phosphodiesterase inhibitor |
EP0579096A2 (en) * | 1992-07-17 | 1994-01-19 | Lusochimica S.P.A. | A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl. |
JPH07252153A (en) * | 1995-01-25 | 1995-10-03 | Otsuka Pharmaceut Co Ltd | Antiarrhythmic agent |
US6022894A (en) * | 1996-04-09 | 2000-02-08 | Nps Pharmaceuticals, Inc. | Method of using calcilytic compounds |
US6432656B1 (en) | 1996-12-03 | 2002-08-13 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
-
1976
- 1976-03-05 JP JP51024492A patent/JPS5936617B2/en not_active Expired
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63290821A (en) * | 1987-05-25 | 1988-11-28 | Otsuka Pharmaceut Co Ltd | Antiarrhythmic |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
US5532253A (en) * | 1991-04-03 | 1996-07-02 | Otsuka Pharmaceutical Company, Limited | Agent for treating thrombosis and phosphodiesterase inhibitor |
WO1992017178A1 (en) * | 1991-04-03 | 1992-10-15 | Otsuka Pharmaceutical Company, Limited | Remedy for thrombosis and phosphodiesterase inhibitor |
US5401754A (en) * | 1991-04-03 | 1995-03-28 | Otsuka Pharmaceutical Company, Limited | Agent for treating thrombosis and phosphodiesterase inhibitor |
EP0579096A2 (en) * | 1992-07-17 | 1994-01-19 | Lusochimica S.P.A. | A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl. |
EP0579096A3 (en) * | 1992-07-17 | 1994-04-27 | Lusochimica Spa | |
JPH07252153A (en) * | 1995-01-25 | 1995-10-03 | Otsuka Pharmaceut Co Ltd | Antiarrhythmic agent |
US6022894A (en) * | 1996-04-09 | 2000-02-08 | Nps Pharmaceuticals, Inc. | Method of using calcilytic compounds |
US6521667B1 (en) | 1996-04-09 | 2003-02-18 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US6432656B1 (en) | 1996-12-03 | 2002-08-13 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS5936617B2 (en) | 1984-09-05 |
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