JPS52108980A - Carbostyril derivatives and their preparation - Google Patents

Carbostyril derivatives and their preparation

Info

Publication number
JPS52108980A
JPS52108980A JP2449276A JP2449276A JPS52108980A JP S52108980 A JPS52108980 A JP S52108980A JP 2449276 A JP2449276 A JP 2449276A JP 2449276 A JP2449276 A JP 2449276A JP S52108980 A JPS52108980 A JP S52108980A
Authority
JP
Japan
Prior art keywords
preparation
carbostyril derivatives
lower alkyl
alkenyl
carbostyril
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2449276A
Other languages
Japanese (ja)
Other versions
JPS5936617B2 (en
Inventor
Kazuyuki Nakagawa
Takao Nishi
Katsuyoshi Yamamoto
Hitoshi Tone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP51024492A priority Critical patent/JPS5936617B2/en
Publication of JPS52108980A publication Critical patent/JPS52108980A/en
Publication of JPS5936617B2 publication Critical patent/JPS5936617B2/en
Expired legal-status Critical Current

Links

Abstract

PURPOSE: Carbostyril derivatives of the formula I (R is H, lower alkyl or alkenyl, etc.; R2 is H, or lower alkyl, alkenyl or cycloalkyl; R3 and R4 are H, or lower alkyl; X is O, S, or imino; Y is hydroxyl, lower alkoxy, amino, phenyl, etc.; l is 0 or 1 ; and m and n are 0 or integers of 1W3), or their salts. For example, 5-[3-(3, 4-dimethoxyphenethylamino)-2-hydroxy] propoxy-3, 4dihydrocarbostyril may be cited.
COPYRIGHT: (C)1977,JPO&Japio
JP51024492A 1976-03-05 1976-03-05 carbostyril derivatives Expired JPS5936617B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP51024492A JPS5936617B2 (en) 1976-03-05 1976-03-05 carbostyril derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51024492A JPS5936617B2 (en) 1976-03-05 1976-03-05 carbostyril derivatives

Publications (2)

Publication Number Publication Date
JPS52108980A true JPS52108980A (en) 1977-09-12
JPS5936617B2 JPS5936617B2 (en) 1984-09-05

Family

ID=12139667

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51024492A Expired JPS5936617B2 (en) 1976-03-05 1976-03-05 carbostyril derivatives

Country Status (1)

Country Link
JP (1) JPS5936617B2 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63290821A (en) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd Antiarrhythmic
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
WO1992017178A1 (en) * 1991-04-03 1992-10-15 Otsuka Pharmaceutical Company, Limited Remedy for thrombosis and phosphodiesterase inhibitor
EP0579096A2 (en) * 1992-07-17 1994-01-19 Lusochimica S.P.A. A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl.
JPH07252153A (en) * 1995-01-25 1995-10-03 Otsuka Pharmaceut Co Ltd Antiarrhythmic agent
US6022894A (en) * 1996-04-09 2000-02-08 Nps Pharmaceuticals, Inc. Method of using calcilytic compounds
US6432656B1 (en) 1996-12-03 2002-08-13 Nps Pharmaceuticals, Inc. Calcilytic compounds
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63290821A (en) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd Antiarrhythmic
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
US5532253A (en) * 1991-04-03 1996-07-02 Otsuka Pharmaceutical Company, Limited Agent for treating thrombosis and phosphodiesterase inhibitor
WO1992017178A1 (en) * 1991-04-03 1992-10-15 Otsuka Pharmaceutical Company, Limited Remedy for thrombosis and phosphodiesterase inhibitor
US5401754A (en) * 1991-04-03 1995-03-28 Otsuka Pharmaceutical Company, Limited Agent for treating thrombosis and phosphodiesterase inhibitor
EP0579096A2 (en) * 1992-07-17 1994-01-19 Lusochimica S.P.A. A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl.
EP0579096A3 (en) * 1992-07-17 1994-04-27 Lusochimica Spa
JPH07252153A (en) * 1995-01-25 1995-10-03 Otsuka Pharmaceut Co Ltd Antiarrhythmic agent
US6022894A (en) * 1996-04-09 2000-02-08 Nps Pharmaceuticals, Inc. Method of using calcilytic compounds
US6521667B1 (en) 1996-04-09 2003-02-18 Nps Pharmaceuticals, Inc. Calcilytic compounds
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
US6432656B1 (en) 1996-12-03 2002-08-13 Nps Pharmaceuticals, Inc. Calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds

Also Published As

Publication number Publication date
JPS5936617B2 (en) 1984-09-05

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