JPS5116430B2 - - Google Patents
Info
- Publication number
- JPS5116430B2 JPS5116430B2 JP46058643A JP5864371A JPS5116430B2 JP S5116430 B2 JPS5116430 B2 JP S5116430B2 JP 46058643 A JP46058643 A JP 46058643A JP 5864371 A JP5864371 A JP 5864371A JP S5116430 B2 JPS5116430 B2 JP S5116430B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (44)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP46058643A JPS5116430B2 (US08063081-20111122-C00115.png) | 1971-08-05 | 1971-08-05 | |
| AU44843/72A AU461281B2 (en) | 1971-08-05 | 1972-07-21 | Novel phthalazone derivatives and process for their manufacture |
| DK366572A DK131857C (da) | 1971-08-05 | 1972-07-24 | Analogifremgangsmade til fremstilling af 4-hydroxymethyl-1-phthalazonderivater eller syreadditionssalte deraf |
| US275171A US3864343A (en) | 1971-08-05 | 1972-07-24 | 7-Alkoxycarbonyl-4-hydroxymethyl-1-phthalazone compounds |
| US00274512A US3840662A (en) | 1971-08-05 | 1972-07-24 | Method of treating atherosclerosis using 4-hydroxymethyl-1-keto-1,2-dihydrophthalazine or acid salts thereof |
| AR243235A AR194123A1 (es) | 1971-08-05 | 1972-07-24 | Un proceso para producir 4-hidroximetil-1-ceto-1,2-dihidroftalazina y sus sales acidas |
| AR243236A AR197089A1 (es) | 1971-08-05 | 1972-07-24 | Proceso para la manufactura de derivados de ftalazona y sales acidas de los mismos |
| IE1046/72A IE36597B1 (en) | 1971-08-05 | 1972-07-25 | Process for preparing a 1,2-dihydrophthalazine |
| GB3482172A GB1404367A (en) | 1971-08-05 | 1972-07-25 | Process for preparing a 1,2-dihydrophthalazine |
| GB3482072A GB1404368A (en) | 1971-08-05 | 1972-07-25 | Phthalazone derivatives |
| AU44940/72A AU461018B2 (en) | 1971-08-05 | 1972-07-25 | Process for producing 4-hydroxymethyl-1-keto-1 2-dihydrophthalazine and acid salts thereof and pharmaceutical composition containing thesame |
| IE1047/72A IE36598B1 (en) | 1971-08-05 | 1972-07-25 | Phthalazone derivatives |
| NL727210370A NL151261B (nl) | 1971-08-05 | 1972-07-27 | Werkwijze voor het bereiden van geneesmiddelen tegen atherosclerose. |
| ZA725202A ZA725202B (en) | 1971-08-05 | 1972-07-27 | Process for producing 4-hydroxymethyl-1-keto-1,2-dihydrophthalazine and acid salts thereof,and pharmaceutical composition containing the same |
| ZA725203A ZA725203B (en) | 1971-08-05 | 1972-07-27 | Novel phthalazone derivatives and process for their manufacturere |
| NL7210369A NL7210369A (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-07-27 | |
| SE7209886A SE408177B (sv) | 1971-08-05 | 1972-07-28 | Forfarande for framstellning av 4-hydroximetyl-1-ftalazonderivat |
| DK377872A DK143159C (da) | 1971-08-05 | 1972-07-31 | Fremgangsmaade til fremstilling af 4-hydroxymethyl-1-keto-1,2-dihydrophthalazin eller syreadditionssalte deraf |
| DE2237832A DE2237832A1 (de) | 1971-08-05 | 1972-08-01 | Verfahren zur herstellung von 4hydroxymethyl-1-keto-1,2-dihydrophthalazin |
| ES405456A ES405456A1 (es) | 1971-08-05 | 1972-08-02 | Un procedimiento para producir 4-hidroximetil-1-ceto-1,2- dihidroftalazina. |
| SE7210119A SE406587B (sv) | 1971-08-05 | 1972-08-03 | Forfarande for framstellning av 4-hydroximetyl-1-keto-1,2-dihydroftalazin |
| SU7201817033A SU577986A3 (ru) | 1971-08-05 | 1972-08-03 | Способ получени производных фталазона или их солей |
| YU2013/72A YU35245B (en) | 1971-08-05 | 1972-08-03 | Process for obtaining novel phthalazone derivatives |
| BE787139A BE787139A (fr) | 1971-08-05 | 1972-08-03 | Nouveaux derives de phthalazone et procede pour leur fabrication |
| BE787138A BE787138A (fr) | 1971-08-05 | 1972-08-03 | Procede de fabrication de la 4-hydroxymethyl-1-ceto-1,2-dihydrophthalazine et de ses sels d'acide et composition pharmaceutique les contenant |
| LU65856A LU65856A1 (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| DE2238566A DE2238566A1 (de) | 1971-08-05 | 1972-08-04 | Neue phthalazonderivate und verfahren zu deren herstellung |
| HUIO186A HU165815B (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| AT852473A AT320658B (de) | 1971-08-05 | 1972-08-04 | Verfahren zur Herstellung von neuen Phthalazonderivaten und von ihren Salzen |
| AT06734/72A AT317233B (de) | 1971-08-05 | 1972-08-04 | Verfahren zur herstellung von 4-hydroxymethyl-1-keto-1,2-dihydrophthalazin und von dessen saeureadditionssalzen |
| CS7200005457A CS180587B2 (en) | 1971-08-05 | 1972-08-04 | Process for preparing phthalazone derivatives |
| CS7200005458A CS180588B2 (en) | 1971-08-05 | 1972-08-04 | Method od producing 4-hydroxymethyl-1-keto-1,2-dihydrophthalazine |
| FR7228258A FR2150736B1 (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| CA148,812A CA966489A (en) | 1971-08-05 | 1972-08-04 | Phthalazone derivatives and process for their manufacture |
| LU65855A LU65855A1 (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| CH1160372A CH580081A5 (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| CA148,813A CA999236A (en) | 1971-08-05 | 1972-08-04 | Process for producing 4-hydroxymethyl-1-keto-1, 2-dlhydrophthalazine and acid salts thereof, and pharmaceutical composition containing the same |
| SU1814854A SU513622A3 (ru) | 1971-08-05 | 1972-08-04 | Способ получени 4-оксиметил-1,2-дигидро-1-фталазона |
| FR7228257A FR2150735B1 (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| HUIO185A HU163726B (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| NO2793/72A NO134113C (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| CH1160472A CH577980A5 (US08063081-20111122-C00115.png) | 1971-08-05 | 1972-08-04 | |
| ES405555A ES405555A1 (es) | 1971-08-05 | 1972-08-04 | Procedimiento para la preparacion de derivados de ftalazo- na. |
| AR249572A AR197156A1 (es) | 1971-08-05 | 1973-08-14 | Proceso para la manufactura de derivados de ftalazona |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP46058643A JPS5116430B2 (US08063081-20111122-C00115.png) | 1971-08-05 | 1971-08-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS4826781A JPS4826781A (US08063081-20111122-C00115.png) | 1973-04-09 |
| JPS5116430B2 true JPS5116430B2 (US08063081-20111122-C00115.png) | 1976-05-24 |
Family
ID=13090247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP46058643A Expired JPS5116430B2 (US08063081-20111122-C00115.png) | 1971-08-05 | 1971-08-05 |
Country Status (23)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205004A1 (es) * | 1973-10-30 | 1976-03-31 | Ishikawa M | Procedimiento para preparar derivados de 6,8-dialquil-7-alcoxi-carbonil-4-hidroximetil-1-ftalazona y la 7,8-lactona |
| NL7702763A (nl) * | 1976-03-18 | 1977-09-20 | Takio Shimamoto En Masayuki Is | Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten. |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| US4293553A (en) * | 1978-08-11 | 1981-10-06 | Masayuki Ishikawa | 1-Phthalazone derivatives, and use thereof |
| US4861778A (en) * | 1986-06-16 | 1989-08-29 | Research Corporation | 2,3-dihydrophthalazine-1,4-diones |
| CH683965A5 (it) * | 1993-02-19 | 1994-06-30 | Limad Marketing Exp & Imp | Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici. |
| DE102005011822A1 (de) * | 2005-03-15 | 2006-09-21 | Merck Patent Gmbh | Phthalazinone |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE687916A (US08063081-20111122-C00115.png) * | 1965-10-12 | 1967-03-16 |
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1971
- 1971-08-05 JP JP46058643A patent/JPS5116430B2/ja not_active Expired
-
1972
- 1972-07-21 AU AU44843/72A patent/AU461281B2/en not_active Expired
- 1972-07-24 AR AR243235A patent/AR194123A1/es active
- 1972-07-24 US US275171A patent/US3864343A/en not_active Expired - Lifetime
- 1972-07-24 DK DK366572A patent/DK131857C/da not_active IP Right Cessation
- 1972-07-24 AR AR243236A patent/AR197089A1/es active
- 1972-07-25 AU AU44940/72A patent/AU461018B2/en not_active Expired
- 1972-07-25 GB GB3482072A patent/GB1404368A/en not_active Expired
- 1972-07-25 GB GB3482172A patent/GB1404367A/en not_active Expired
- 1972-07-25 IE IE1046/72A patent/IE36597B1/xx unknown
- 1972-07-25 IE IE1047/72A patent/IE36598B1/xx unknown
- 1972-07-27 ZA ZA725202A patent/ZA725202B/xx unknown
- 1972-07-27 NL NL7210369A patent/NL7210369A/xx unknown
- 1972-07-27 NL NL727210370A patent/NL151261B/xx not_active IP Right Cessation
- 1972-07-27 ZA ZA725203A patent/ZA725203B/xx unknown
- 1972-07-28 SE SE7209886A patent/SE408177B/xx unknown
- 1972-07-31 DK DK377872A patent/DK143159C/da not_active IP Right Cessation
- 1972-08-01 DE DE2237832A patent/DE2237832A1/de active Pending
- 1972-08-02 ES ES405456A patent/ES405456A1/es not_active Expired
- 1972-08-03 BE BE787138A patent/BE787138A/xx not_active IP Right Cessation
- 1972-08-03 SE SE7210119A patent/SE406587B/xx unknown
- 1972-08-03 YU YU2013/72A patent/YU35245B/xx unknown
- 1972-08-03 SU SU7201817033A patent/SU577986A3/ru active
- 1972-08-03 BE BE787139A patent/BE787139A/xx not_active IP Right Cessation
- 1972-08-04 NO NO2793/72A patent/NO134113C/no unknown
- 1972-08-04 FR FR7228258A patent/FR2150736B1/fr not_active Expired
- 1972-08-04 CH CH1160472A patent/CH577980A5/xx not_active IP Right Cessation
- 1972-08-04 ES ES405555A patent/ES405555A1/es not_active Expired
- 1972-08-04 HU HUIO186A patent/HU165815B/hu unknown
- 1972-08-04 LU LU65856A patent/LU65856A1/xx unknown
- 1972-08-04 LU LU65855A patent/LU65855A1/xx unknown
- 1972-08-04 HU HUIO185A patent/HU163726B/hu unknown
- 1972-08-04 CA CA148,813A patent/CA999236A/en not_active Expired
- 1972-08-04 AT AT852473A patent/AT320658B/de not_active IP Right Cessation
- 1972-08-04 CA CA148,812A patent/CA966489A/en not_active Expired
- 1972-08-04 CS CS7200005457A patent/CS180587B2/cs unknown
- 1972-08-04 CS CS7200005458A patent/CS180588B2/cs unknown
- 1972-08-04 AT AT06734/72A patent/AT317233B/de not_active IP Right Cessation
- 1972-08-04 CH CH1160372A patent/CH580081A5/xx not_active IP Right Cessation
- 1972-08-04 SU SU1814854A patent/SU513622A3/ru active
- 1972-08-04 FR FR7228257A patent/FR2150735B1/fr not_active Expired
- 1972-08-04 DE DE2238566A patent/DE2238566A1/de active Pending
-
1973
- 1973-08-14 AR AR249572A patent/AR197156A1/es active
