JPS50653B1 - - Google Patents
Info
- Publication number
- JPS50653B1 JPS50653B1 JP41004651A JP465166A JPS50653B1 JP S50653 B1 JPS50653 B1 JP S50653B1 JP 41004651 A JP41004651 A JP 41004651A JP 465166 A JP465166 A JP 465166A JP S50653 B1 JPS50653 B1 JP S50653B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE571165 | 1965-04-30 | ||
| US55822666A | 1966-06-17 | 1966-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS50653B1 true JPS50653B1 (e) | 1975-01-10 |
Family
ID=26654650
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP41004651A Pending JPS50653B1 (e) | 1965-04-30 | 1966-01-28 | |
| JP45120574A Pending JPS4929182B1 (e) | 1965-04-30 | 1970-12-28 | |
| JP47124826A Pending JPS4930819B1 (e) | 1965-04-30 | 1972-12-14 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP45120574A Pending JPS4929182B1 (e) | 1965-04-30 | 1970-12-28 | |
| JP47124826A Pending JPS4930819B1 (e) | 1965-04-30 | 1972-12-14 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US3466325A (e) |
| JP (3) | JPS50653B1 (e) |
| BE (1) | BE678208A (e) |
| BR (1) | BR6678981D0 (e) |
| CH (1) | CH484053A (e) |
| DE (1) | DE1294955B (e) |
| FI (2) | FI42955B (e) |
| FR (1) | FR5745M (e) |
| GB (2) | GB1140860A (e) |
| NL (1) | NL143550B (e) |
| NO (1) | NO115797B (e) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3969512A (en) * | 1935-11-15 | 1976-07-13 | Boehringer Ingelheim Gmbh | N,N'bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamines and salts thereof |
| SE354851B (e) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
| US4059622A (en) * | 1970-05-27 | 1977-11-22 | Imperial Chemical Industries Limited | Alkanolamine derivatives |
| US3959486A (en) * | 1970-05-27 | 1976-05-25 | Imperial Chemical Industries Limited | Method for producing β-adrenergic blockage with alkanolamine derivatives |
| SE386892B (sv) * | 1972-07-06 | 1976-08-23 | Haessle Ab | Forfarande for framstellning av oxaminoforeningar |
| US4018825A (en) * | 1972-07-27 | 1977-04-19 | Warner-Lambert Company | 5-Hydroxy-α-(substituted aminomethyl)-m-xylene-α,α'-diols |
| US4119729A (en) * | 1975-12-19 | 1978-10-10 | Mead Johnson & Company | Alkylsulfonylphenoxypropanolamine therapeutic process |
| US4067904A (en) * | 1975-12-19 | 1978-01-10 | Mead Johnson & Company | Alkylsulfonylphenoxypropanolamine derivatives |
| US4243681A (en) * | 1977-10-11 | 1981-01-06 | Mead Johnson & Company | Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof |
| EP0013258B1 (de) * | 1978-12-29 | 1982-07-07 | Ciba-Geigy Ag | Propenylsubstituierte Phenolglycidyläther, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US4945182A (en) * | 1985-12-24 | 1990-07-31 | Merck & Co., Inc. | Oculoselective beta-blockers |
| US5254595A (en) * | 1988-12-23 | 1993-10-19 | Elf Sanofi | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them |
| JP2780559B2 (ja) * | 1991-01-25 | 1998-07-30 | 信越化学工業株式会社 | アリル基又はプロペニル基を持つナフタレン誘導体 |
| CA2134038C (en) * | 1994-06-16 | 1997-06-03 | David Taiwai Wong | Potentiation of drug response |
| EP0714663A3 (en) | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potentiation of drug responses by serotonin 1A receptor antagonists |
| DE69607904T2 (de) * | 1995-08-16 | 2000-10-05 | Eli Lilly And Co., Indianapolis | Potenzierung von Serotonin-Wirkstoffresponz |
| US7034059B2 (en) * | 2001-07-02 | 2006-04-25 | Sepracor Inc. | Methods of using norfluoxetine |
| US20030087963A1 (en) | 2001-09-13 | 2003-05-08 | Senanayake Chris H. | Methods of preparing and using 2-hydroxy derivatives of sibutramine and its metabolites |
| AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
| CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EP2050441A1 (en) * | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| RS65632B1 (sr) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Ltd | Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe |
| EP2959904A1 (en) | 2014-06-27 | 2015-12-30 | Institut De Recerca Contra La Leucemia Josep Carreras | Methods for treating, diagnosing and prognosing a haematological malignancy |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| FR3030514A1 (fr) * | 2014-12-18 | 2016-06-24 | Centre De Coop Int En Rech Agronomique Pour Le Dev (Cirad) | Dimeres polyaromatiques |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6409883A (e) * | 1963-08-26 | 1965-03-01 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2967201A (en) * | 1958-06-02 | 1961-01-03 | Lilly Co Eli | Alkylaminoalkyl ethers of phenols |
| NL300886A (e) * | 1962-11-23 | |||
| NL301580A (e) * | 1962-12-11 | |||
| GB1069345A (en) * | 1963-07-19 | 1967-05-17 | Ici Ltd | New alkanolamine derivatives |
| NL131194C (e) * | 1963-07-19 | |||
| CH455834A (de) * | 1964-10-14 | 1968-05-15 | Ciba Geigy | Verfahren zur Herstellung des neuen 1-Isopropylamino-2-hydroxy-3-(2'-isopropoxy-phenoxy)-propans oder seinen Salzen |
-
1966
- 1966-01-18 US US521436A patent/US3466325A/en not_active Expired - Lifetime
- 1966-01-26 GB GB40546/68A patent/GB1140860A/en not_active Expired
- 1966-01-26 GB GB3531/66A patent/GB1140508A/en not_active Expired
- 1966-01-28 JP JP41004651A patent/JPS50653B1/ja active Pending
- 1966-01-29 DE DEA51453A patent/DE1294955B/de active Pending
- 1966-03-22 BE BE678208D patent/BE678208A/xx not_active IP Right Cessation
- 1966-03-31 CH CH469666A patent/CH484053A/de not_active IP Right Cessation
- 1966-04-05 NO NO162482A patent/NO115797B/no unknown
- 1966-04-26 FI FI1089/66A patent/FI42955B/fi active
- 1966-04-26 BR BR178981/66A patent/BR6678981D0/pt unknown
- 1966-04-27 FR FR59328A patent/FR5745M/fr not_active Expired
- 1966-04-28 NL NL666605692A patent/NL143550B/xx not_active IP Right Cessation
- 1966-06-17 US US558226A patent/US3466376A/en not_active Expired - Lifetime
-
1969
- 1969-08-15 US US872789*A patent/US3631108A/en not_active Expired - Lifetime
-
1970
- 1970-04-03 FI FI0931/70A patent/FI44392B/fi active
- 1970-12-28 JP JP45120574A patent/JPS4929182B1/ja active Pending
-
1972
- 1972-12-14 JP JP47124826A patent/JPS4930819B1/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6409883A (e) * | 1963-08-26 | 1965-03-01 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR5745M (e) | 1968-01-29 |
| GB1140860A (en) | 1969-01-22 |
| NL143550B (nl) | 1974-10-15 |
| DE1294955B (de) | 1969-05-14 |
| GB1140508A (en) | 1969-01-22 |
| US3466325A (en) | 1969-09-09 |
| FI42955B (e) | 1970-09-02 |
| CH484053A (de) | 1970-01-15 |
| US3466376A (en) | 1969-09-09 |
| JPS4929182B1 (e) | 1974-08-01 |
| BR6678981D0 (pt) | 1973-09-18 |
| BE678208A (e) | 1966-09-01 |
| FI44392B (e) | 1971-08-02 |
| JPS4930819B1 (e) | 1974-08-16 |
| NO115797B (e) | 1968-12-09 |
| NL6605692A (e) | 1966-10-31 |
| US3631108A (en) | 1971-12-28 |