JPS5058084A - - Google Patents
Info
- Publication number
- JPS5058084A JPS5058084A JP49102876A JP10287674A JPS5058084A JP S5058084 A JPS5058084 A JP S5058084A JP 49102876 A JP49102876 A JP 49102876A JP 10287674 A JP10287674 A JP 10287674A JP S5058084 A JPS5058084 A JP S5058084A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39480173A | 1973-09-06 | 1973-09-06 | |
US05/459,774 US4585788A (en) | 1973-09-06 | 1974-04-10 | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5058084A true JPS5058084A (en) | 1975-05-20 |
Family
ID=27014870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP49102876A Pending JPS5058084A (en) | 1973-09-06 | 1974-09-06 |
Country Status (17)
Country | Link |
---|---|
US (1) | US4585788A (en) |
JP (1) | JPS5058084A (en) |
AT (1) | AT342053B (en) |
AU (1) | AU499709B2 (en) |
CA (1) | CA1153384A (en) |
CH (2) | CH609960A5 (en) |
DE (1) | DE2442060A1 (en) |
DK (1) | DK470574A (en) |
FI (1) | FI66368C (en) |
FR (1) | FR2242976B1 (en) |
GB (1) | GB1481866A (en) |
IE (1) | IE39835B1 (en) |
IL (1) | IL45585A (en) |
NL (1) | NL7411565A (en) |
NO (1) | NO142397C (en) |
SE (1) | SE7411156L (en) |
YU (2) | YU239574A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990003373A1 (en) * | 1988-09-20 | 1990-04-05 | Hisamitsu Pharmaceutical Co., Inc. | NOVEL DIBENZ[b,e]OXEPIN DERIVATIVES |
JPH0390077A (en) * | 1989-08-25 | 1991-04-16 | Hoechst Roussel Pharmaceut Inc | N-hydroxydibenz (b,e) oxepinealkylamines and -alkane acide amides |
WO2008023810A1 (en) * | 2006-08-21 | 2008-02-28 | Sumitomo Chemical Company, Limited | 2-(4-methoxycarbonylmethylphenoxymethyl)benzoic acid methyl ester and method for producing the same |
JP2008110966A (en) * | 2006-10-02 | 2008-05-15 | Sumitomo Chemical Co Ltd | Manufacturing method of tertiary alkyl oxodibenzooxepine acetate |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56156273A (en) | 1980-03-31 | 1981-12-02 | Dainippon Pharmaceut Co Ltd | Acetic derivative |
DE3125374A1 (en) * | 1981-06-27 | 1983-01-13 | Hoechst Ag, 6000 Frankfurt | METHOD FOR PRODUCING HETEROARYL AND DIBENZOXEPINALKAN ACIDS |
US4515946A (en) * | 1981-12-23 | 1985-05-07 | Hoechst-Roussel Pharmaceuticals Inc. | 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives |
US4576960A (en) * | 1981-12-23 | 1986-03-18 | Hoechst Roussel Pharmaceuticals Incorporated | 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives |
US4526891A (en) * | 1983-03-10 | 1985-07-02 | Hoechst Roussel Pharmaceuticals Inc. | Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins |
EP0188802A3 (en) * | 1984-12-26 | 1986-08-20 | Kyowa Hakko Kogyo Co., Ltd. | Dibenz (b,e) oxepin derivative and antiallergic agent |
FR2580280B1 (en) * | 1985-04-11 | 1987-05-22 | Synthelabo | DIBENZO (BE) OXEPINNE-ACETIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
JPS6310784A (en) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | Dibenz(b,e)oxepin derivative, antiallergic agent and anti-inflammatory agent |
FR2608606B1 (en) * | 1986-12-22 | 1989-03-10 | Synthelabo | DIBENZO (BE) OXEPINNE-ACETIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
US4882351A (en) * | 1987-10-14 | 1989-11-21 | Roussel Uclaf | Tricyclic compounds |
US4994463A (en) * | 1987-12-14 | 1991-02-19 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic thromboxane A2 antagonists |
US4999363A (en) * | 1988-06-09 | 1991-03-12 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5242931A (en) * | 1988-06-09 | 1993-09-07 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds as TXA2 antagonists |
US5840749A (en) * | 1989-08-25 | 1998-11-24 | Hoechst Marion Roussel, Inc. | N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues |
US5574173A (en) * | 1993-12-06 | 1996-11-12 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
US6989462B2 (en) * | 2003-03-25 | 2006-01-24 | Sanofi-Aventis Deutschland Gmbh | Synthesis of 2-chloromethyl-6-methylbenzoic ester |
US7687646B2 (en) * | 2006-03-28 | 2010-03-30 | Azad Pharmaceutical Ingredients, Ag | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof |
ES2409840T3 (en) * | 2006-10-02 | 2013-06-28 | Sumitomo Chemical Co., Ltd | Process for the preparation of olopatadine |
ES2433715T3 (en) | 2008-07-16 | 2013-12-12 | Crystal Pharma, S.A.U. | Procedure for obtaining olopatadine and intermediates |
CN106518833A (en) * | 2015-09-15 | 2017-03-22 | 江苏吉贝尔药业股份有限公司 | New method for preparation of 6,11-dihydro-11-oxo dibenzo [b, e] oxepin-2-acetic acid |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS47425Y1 (en) * | 1968-03-14 | 1972-01-10 | ||
JPS48389Y1 (en) * | 1968-10-15 | 1973-01-08 | ||
US3702852A (en) * | 1970-02-24 | 1972-11-14 | Squibb & Sons Inc | Carboxylated dibenzoxazepines and dibenzothiazepines |
US3758528A (en) * | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
US3714201A (en) * | 1970-11-24 | 1973-01-30 | Squibb & Sons Inc | 5,11-dihydrodibenzoxa(or thia) zepine derivatives |
-
1974
- 1974-04-10 US US05/459,774 patent/US4585788A/en not_active Expired - Lifetime
- 1974-08-30 NL NL7411565A patent/NL7411565A/en not_active Application Discontinuation
- 1974-09-03 DE DE2442060A patent/DE2442060A1/en not_active Withdrawn
- 1974-09-03 IL IL7445585A patent/IL45585A/en unknown
- 1974-09-03 CH CH675378A patent/CH609960A5/xx not_active IP Right Cessation
- 1974-09-03 CH CH1195574A patent/CH615172A5/de not_active IP Right Cessation
- 1974-09-04 FI FI2583/74A patent/FI66368C/en active
- 1974-09-04 SE SE7411156A patent/SE7411156L/xx unknown
- 1974-09-04 AU AU72962/74A patent/AU499709B2/en not_active Expired
- 1974-09-05 AT AT716474A patent/AT342053B/en not_active IP Right Cessation
- 1974-09-05 DK DK470574A patent/DK470574A/da not_active Application Discontinuation
- 1974-09-05 NO NO74743203A patent/NO142397C/en unknown
- 1974-09-05 CA CA000208542A patent/CA1153384A/en not_active Expired
- 1974-09-05 IE IE1847/74A patent/IE39835B1/en unknown
- 1974-09-06 FR FR7430329A patent/FR2242976B1/fr not_active Expired
- 1974-09-06 GB GB39112/74A patent/GB1481866A/en not_active Expired
- 1974-09-06 JP JP49102876A patent/JPS5058084A/ja active Pending
- 1974-09-15 YU YU02395/74A patent/YU239574A/en unknown
-
1980
- 1980-09-12 YU YU02338/80A patent/YU233880A/en unknown
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990003373A1 (en) * | 1988-09-20 | 1990-04-05 | Hisamitsu Pharmaceutical Co., Inc. | NOVEL DIBENZ[b,e]OXEPIN DERIVATIVES |
JPH0390077A (en) * | 1989-08-25 | 1991-04-16 | Hoechst Roussel Pharmaceut Inc | N-hydroxydibenz (b,e) oxepinealkylamines and -alkane acide amides |
WO2008023810A1 (en) * | 2006-08-21 | 2008-02-28 | Sumitomo Chemical Company, Limited | 2-(4-methoxycarbonylmethylphenoxymethyl)benzoic acid methyl ester and method for producing the same |
JP2008110966A (en) * | 2006-10-02 | 2008-05-15 | Sumitomo Chemical Co Ltd | Manufacturing method of tertiary alkyl oxodibenzooxepine acetate |
Also Published As
Publication number | Publication date |
---|---|
SE7411156L (en) | 1975-03-07 |
NO142397B (en) | 1980-05-05 |
GB1481866A (en) | 1977-08-03 |
DK470574A (en) | 1975-05-05 |
AT342053B (en) | 1978-03-10 |
CH609960A5 (en) | 1979-03-30 |
US4585788A (en) | 1986-04-29 |
IE39835L (en) | 1975-03-06 |
IL45585A (en) | 1977-06-30 |
FI258374A (en) | 1975-03-07 |
AU499709B2 (en) | 1979-05-03 |
FR2242976A1 (en) | 1975-04-04 |
DE2442060A1 (en) | 1975-05-07 |
NO142397C (en) | 1980-08-13 |
FR2242976B1 (en) | 1978-07-21 |
FI66368B (en) | 1984-06-29 |
NL7411565A (en) | 1975-03-10 |
IE39835B1 (en) | 1979-01-17 |
YU239574A (en) | 1982-06-18 |
CH615172A5 (en) | 1980-01-15 |
IL45585A0 (en) | 1974-11-29 |
YU233880A (en) | 1983-04-27 |
ATA716474A (en) | 1977-07-15 |
AU7296274A (en) | 1976-04-15 |
NO743203L (en) | 1975-04-01 |
FI66368C (en) | 1984-10-10 |
CA1153384A (en) | 1983-09-06 |