JPS505518A - - Google Patents

Info

Publication number
JPS505518A
JPS505518A JP49004829A JP482974A JPS505518A JP S505518 A JPS505518 A JP S505518A JP 49004829 A JP49004829 A JP 49004829A JP 482974 A JP482974 A JP 482974A JP S505518 A JPS505518 A JP S505518A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP49004829A
Other languages
Japanese (ja)
Other versions
JPS5939428B2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26981949&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS505518(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of JPS505518A publication Critical patent/JPS505518A/ja
Publication of JPS5939428B2 publication Critical patent/JPS5939428B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP744829A 1972-12-29 1973-12-26 Method for producing a 5(6)-benzene ring-substituted benzimidazole-2-carbamate derivative having anthelmintic effect Expired JPS5939428B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31929972A 1972-12-29 1972-12-29
US319299 1972-12-29
US417963A US3929821A (en) 1972-12-29 1973-11-21 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives
US417963 1973-11-21

Publications (2)

Publication Number Publication Date
JPS505518A true JPS505518A (en) 1975-01-21
JPS5939428B2 JPS5939428B2 (en) 1984-09-22

Family

ID=26981949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP744829A Expired JPS5939428B2 (en) 1972-12-29 1973-12-26 Method for producing a 5(6)-benzene ring-substituted benzimidazole-2-carbamate derivative having anthelmintic effect

Country Status (25)

Country Link
US (1) US3929821A (en)
JP (1) JPS5939428B2 (en)
AR (2) AR216037A1 (en)
AT (1) AT332883B (en)
BR (1) BR7310296D0 (en)
CH (2) CH608006A5 (en)
CS (1) CS187390B2 (en)
DE (3) DE2366070C2 (en)
DK (1) DK137329B (en)
ES (2) ES421927A1 (en)
FR (1) FR2212150B1 (en)
GB (2) GB1456497A (en)
HK (1) HK8280A (en)
HU (1) HU169272B (en)
IE (1) IE40046B1 (en)
IL (1) IL43860A (en)
IN (1) IN138644B (en)
IT (1) IT1046097B (en)
MY (1) MY8000273A (en)
NL (1) NL169738C (en)
PL (1) PL95987B1 (en)
RO (1) RO67150A (en)
SE (1) SE414402B (en)
SU (1) SU727143A3 (en)
YU (2) YU36706B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5598168A (en) * 1978-12-06 1980-07-25 Montedison Spa Benzimidazoleecarbamate
JPS5690065A (en) * 1979-10-19 1981-07-21 Chinoin Gyogyszer Es Vegyeszet Benzimidazole derivative and its manufacture
JPH07500612A (en) * 1992-03-12 1995-01-19 ファイザー・インコーポレーテッド benzimidazole anthelmintic
JP2009502858A (en) * 2005-07-28 2009-01-29 インターベツト・インターナシヨナル・ベー・ベー Novel benzimidazole (thio) carbamate with antiparasitic activity and its synthesis

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002640A (en) * 1972-12-29 1977-01-11 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4258198A (en) * 1973-05-29 1981-03-24 Smithkline Corporation 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles
DE2441201C2 (en) * 1974-08-28 1986-08-07 Hoechst Ag, 6230 Frankfurt 2-Carbalkoxyamino-5 (6) -phenyl-sulfonyloxy-benzimidazoles and process for their preparation
DE2441202C2 (en) * 1974-08-28 1986-05-28 Hoechst Ag, 6230 Frankfurt 2-Carbalkoxyamino-benzimidazolyl-5 (6) -sulfonic acid-phenyl ester, process for their preparation and anthelmintic compositions containing them
US4086235A (en) * 1976-04-12 1978-04-25 Syntex (U.S.A.) Inc. 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
USRE30990E (en) * 1976-07-16 1982-07-06 E. R. Squibb & Sons, Inc. Benzimidazole derivatives, compositions thereof and method of use as anthelmintics
US4046908A (en) * 1976-07-16 1977-09-06 E. R. Squibb & Sons, Inc. Benzimidazole derivatives, compositions thereof and method of use as anthelmintics
AU515740B2 (en) * 1976-08-13 1981-04-30 Wellcome Foundation Limited, The Veterinary compositions
NZ184906A (en) * 1976-08-13 1980-10-24 Wellcome Found Flukicidal compositions based on a synergistic combination of a di- (4-acylaminophenoxy)-ether and a potentiating benzimidazole
FR2362116A1 (en) * 1976-08-20 1978-03-17 Oreal METAPHENYLENEDIAMINES AND TINCTORIAL COMPOSITIONS CONTAINING THEM
US4093732A (en) * 1977-02-17 1978-06-06 E. R. Squibb & Sons, Inc. Sulfoxide derivatives of benzimidazoles
IT1076022B (en) * 1977-04-20 1985-04-22 Montedison Spa ANTIELMINTIC BENZIMIDAZOLCARBAMMATES
IT1107749B (en) * 1977-10-06 1985-11-25 Montedison Spa BENZIMIDAZOLCARBAMMATE PARTICULARLY ACTIVE AGAINST GASTROENTERIC AND PULMONARY PARASITES
US4152522A (en) * 1978-01-03 1979-05-01 Ethyl Corporation Process for the preparation of 2-benzimidazole carbamates
US4156006A (en) * 1978-01-09 1979-05-22 E. R. Squibb & Sons, Inc. Vinyl sulfide derivatives of benzimidazoles
US4136174A (en) * 1978-01-18 1979-01-23 E. R. Squibb & Sons, Inc. Benzimidazolecarbamates and method
JPS54104837A (en) * 1978-02-03 1979-08-17 Nippon Denso Co Ltd Controller of copying machines
US4145431A (en) * 1978-02-16 1979-03-20 E. R. Squibb & Sons, Inc. Method of treating helminthiasis by parenteral administration of sulfide- and sulfoxide-derivatives of benzimidazoles
US4154846A (en) * 1978-06-16 1979-05-15 E. R. Squibb & Sons, Inc. Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates
US4174400A (en) * 1978-09-13 1979-11-13 Merck & Co., Inc. Anthelmintic benzimidazoles
DE2845537A1 (en) * 1978-10-19 1980-04-30 Bayer Ag BENZIMIDAZOLYLCARBAMID ACID ESTER, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
DD147539A5 (en) * 1978-12-06 1981-04-08 Montedison Spa PREPARATION OF BENZIMIDAZOLE CARBAMATES SUBSTITUTED IN 5 (6) POSITION
US4198422A (en) * 1979-05-17 1980-04-15 E. R. Squibb & Sons, Inc. Substituted 2,3-naphthimidazole carbamates and method
EP0028455A1 (en) * 1979-10-12 1981-05-13 Imperial Chemical Industries Plc 5-Phenylselenobenzimidazole derivatives, their preparation and anthelmintic or fasciolicidal compositions containing them
IL61232A (en) * 1979-10-19 1985-09-29 Chinoin Gyogyszer Es Vegyeszet Process for the preparation of 2-amino(or alkoxycarbonylamino)-5(6)-thiocyanato(or thiol)benzimidazole derivatives
US4599428A (en) * 1979-10-19 1986-07-08 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt Process for the preparation of 5(6)-thio substituted benzimidazoles
US4299837A (en) 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates
DE3719783A1 (en) * 1987-06-13 1988-12-22 Hoechst Ag METHOD FOR PRODUCING 5-PHENYLSULFINYL-1H-2- (METHOXYCARBONYLAMINO) - BENZIMIDAZOLE
US6593466B1 (en) * 1999-07-07 2003-07-15 Isis Pharmaceuticals, Inc. Guanidinium functionalized nucleotides and precursors thereof
WO2008091358A1 (en) * 2006-06-12 2008-07-31 Smith And Nephew Inc Systems, methods and devices for tibial resection
MX2008015764A (en) 2006-06-14 2009-01-07 Intervet Int Bv A suspension comprising benzimidazole carbamate and a polysorbate.
CN102241635A (en) * 2011-04-28 2011-11-16 江苏宝众宝达药业有限公司 Preparation method for anthelmintic benzimidazole fenbendazole
CN102863392A (en) * 2012-10-18 2013-01-09 江苏宝众宝达药业有限公司 Method for greatly reducing amount of solvent usage in production process of oxfendazole

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3480642A (en) * 1967-03-22 1969-11-25 Smithkline Corp Process for producing 2-carbalkoxyaminobenzimidazoles
FR2059938A1 (en) * 1969-03-14 1971-06-11 Aries Robert 1-haloalk(en)yl sulphenyl-2-aryloxycarbon-yl -
US3657267A (en) * 1969-06-20 1972-04-18 Janssen Pharmaceutica Nv Benzimidazole carbamates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2933502A (en) * 1958-02-12 1960-04-19 Du Pont Benzimidazolone derivatives
US2933504A (en) * 1959-08-10 1960-04-19 Du Pont Derivatives of polyalkoxycarbonyl imine
US3010968A (en) 1959-11-25 1961-11-28 Du Pont Process for manufacture of certain alkyl esters of benzimidazole carbamic acids
BE666795A (en) * 1964-08-04 1966-01-13
US3506767A (en) * 1965-08-06 1970-04-14 Geigy Chem Corp Benzimidazole compositions and methods of use
US3401171A (en) * 1966-03-11 1968-09-10 Smithkline Corp 2-amidobenzimidazoles
CH456236A (en) * 1966-05-06 1968-07-15 Agripat Sa Process for protecting textile keratinous fiber materials from insect damage and means for carrying out this process
CH490010A (en) * 1967-10-26 1970-05-15 Ciba Geigy Pesticides
US3562290A (en) * 1967-11-07 1971-02-09 Du Pont Process for making 2-benzimidazolecarbamic acid alkyl esters
US3714180A (en) * 1970-08-12 1973-01-30 Squibb & Sons Inc Sulfonyl benzimidazoles
US3694455A (en) * 1970-11-19 1972-09-26 Smith Kline French Lab Acyloxyalkyl amidobenzimidazoles
US3720686A (en) * 1971-04-01 1973-03-13 Squibb & Sons Inc Mercaptobenzimidazole derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3480642A (en) * 1967-03-22 1969-11-25 Smithkline Corp Process for producing 2-carbalkoxyaminobenzimidazoles
FR2059938A1 (en) * 1969-03-14 1971-06-11 Aries Robert 1-haloalk(en)yl sulphenyl-2-aryloxycarbon-yl -
US3657267A (en) * 1969-06-20 1972-04-18 Janssen Pharmaceutica Nv Benzimidazole carbamates

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5598168A (en) * 1978-12-06 1980-07-25 Montedison Spa Benzimidazoleecarbamate
JPS5690065A (en) * 1979-10-19 1981-07-21 Chinoin Gyogyszer Es Vegyeszet Benzimidazole derivative and its manufacture
JPH07500612A (en) * 1992-03-12 1995-01-19 ファイザー・インコーポレーテッド benzimidazole anthelmintic
JP2009502858A (en) * 2005-07-28 2009-01-29 インターベツト・インターナシヨナル・ベー・ベー Novel benzimidazole (thio) carbamate with antiparasitic activity and its synthesis

Also Published As

Publication number Publication date
DK137329C (en) 1978-07-24
MY8000273A (en) 1980-12-31
DE2366069C2 (en) 1987-06-11
GB1456497A (en) 1976-11-24
PL95987B1 (en) 1977-11-30
AT332883B (en) 1976-10-25
YU64180A (en) 1983-04-30
NL169738B (en) 1982-03-16
IE40046L (en) 1974-06-29
IT1046097B (en) 1980-06-30
CH608006A5 (en) 1978-12-15
ATA1075173A (en) 1976-02-15
YU36706B (en) 1984-08-31
HK8280A (en) 1980-03-14
RO67150A (en) 1980-12-30
DK137329B (en) 1978-02-20
IN138644B (en) 1976-03-06
JPS5939428B2 (en) 1984-09-22
DE2363351A1 (en) 1974-07-11
AR221816A1 (en) 1981-03-31
AR216037A1 (en) 1979-11-30
YU337173A (en) 1981-11-13
DE2366069A1 (en) 1977-11-10
CH613955A5 (en) 1979-10-31
DE2366070C2 (en) 1987-06-11
ES421927A1 (en) 1977-01-01
NL7317797A (en) 1974-07-02
SE414402B (en) 1980-07-28
SU727143A3 (en) 1980-04-05
IL43860A (en) 1977-05-31
YU40868B (en) 1986-06-30
AU6367473A (en) 1975-06-19
DE2363351C2 (en) 1987-03-12
CS187390B2 (en) 1979-01-31
FR2212150B1 (en) 1977-01-28
ES445257A1 (en) 1977-10-01
IL43860A0 (en) 1974-03-14
BR7310296D0 (en) 1974-09-24
GB1455728A (en) 1976-11-17
HU169272B (en) 1976-10-28
NL169738C (en) 1982-08-16
US3929821A (en) 1975-12-30
FR2212150A1 (en) 1974-07-26
IE40046B1 (en) 1979-02-28

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